HOLLANDE1 considered that living protoplasm in in general consisted of filamentous, hyaline tubes with numerous clusters, made up of two punctiform corpuscles, distributed over their surface ; and that the nucleus had a comparable structure. Hollande and Hollande2 made similar findings for Bacteria and Cyanophycese. Drennan3, studying human blood, described granules which moved freely in the serum and which were of different kinds, as they reacted differently to stains and varied in size and degree of motility. Sparrow and Hammond4 noted Feulgen-positive bodies in the cytoplasm of the meiotic prophase stages of microsporocytes in eleven different flowering plants. These bodies appeared to originate in the nucleus or at the nuclear membrane. They regarded the positive Feulgen reaction together with high absorption at 2537 A. and 2650 A. as proof that the bodies contained desoxyribose nucleic acid, and strong absorption at 2804 A. as an indication that protein also was present. Calvet, Siegel and Stern5, as a result of electron optical observations, reported that the resting nuclei of calf thymus lymphocytes, treated with lanthanum acetate, showed nucleoprotein ultra-fibrils of approximate thickness 80–100 A. These appeared banded. They concluded that the banded appearance was probably due to the coiling of a fine thread to form long helices and that the spirals might lbe formed by individual desoxyribonucleoprotein molecules in combination with lanthanum ions. Malvesin-Fabre6 found, in the living nuclei of Arum italicum, that there were chromocentres which continuously changed their form and appearance and that the nucleus showed continuous activity in the resting stage. Ritche7, working on fixed and stained basidia of Amanita cæsaria, found extra-nuclear inclusions, frequently near the base of the basidium, which were readily stained with hsematoxylin and were Feulgen-positive. He regarded them as chromatic in nature.