By analyzing the evolutionary spectrum method for multivariate nonstationary stochastic processes, a simulation method for fully nonstationary spatially variable ground motion is proposed based on the Kameda time-varying power spectrum model. This method can properly simulate nonstationary spatially variable ground motion based on a target response spectrum. Two numerical examples, in which the Kameda time-varying power spectra are calculated for different conditions, are presented to demonstrate the capabilities of the proposed method. In the first example, the nonstationary spatially variable ground motion that satisfies the time-frequency characteristics and response characteristics of the original ground motion is simulated by identifying the parameters of the given time-varying power spectrum. In the second example, the ground motion that satisfies the design response spectra is simulated by defining the parameters of the time-varying power spectrum directly. The results demonstrate that the method can effectively simulate nonstationary spatially variable ground motion, which implies that the proposed method can be used in engineering applications.