The prestressed concrete box-girder with corrugated steel webs is a new type of steel-concrete composite structure. It has some advantages comparing with traditional prestressed concrete structure. Shear connector is a decisive component with which steel and concrete can work together in steel-concrete composite structure. In this paper, the most commonly used forms of shear connector in prestressed concrete composite girder with corrugated steel webs are introduced. The method of design and calculation of shear connector is described. Furthermore, the engineering design case of shear connector in the 4th Nanjing Yangtze River Bridge North Terminal Chuhe Bridge is presented. The method can be taken as a reference to the design of shear connector in the same kind bridge.