Theoretically, protonic ceramic fuel cells (PCFCs) are considered to achieve higher energy conversion efficiencies than conventional solid oxide fuel cells. However, doped barium-based perovskite oxide, a typical electrolyte material, has a significant leakage current derived from hole conduction. Therefore, it is still unclear whether the actual performance of whole PCFC systems can reach the expected high efficiency. In this study, two strategies to suppress the leakage current, namely, low-temperature operation and a bilayer electrolyte cell using a high-ion and low-hole conductor, were discussed. The effects of these approaches on production costs and system efficiency were investigated from an economic perspective for social implementation. Moreover, the following technological options were discussed to comprehensively investigate the effects of cell, manufacturing process, and system designs on the system efficiencies and system costs; (1) cell design: examining a high-performance electrode; (2) module production process design: examining the annual production rate, co-sintering of electrode and electrolyte layers, and fabrication of an electrolyte layer with vapor-phase deposition; and (3) system design: examining a methane-fueled system, a multi-stage PCFC operation, a membrane for hydrogen separation, and lower oxygen utilization. Here, we focused on a residential 5 kW alternating current (AC) class system. Consequently, system efficiency and module production cost were calculated as 57 % based on the lower heating value (LHV) in a direct current (DC) and 4,650 USD/system adopting a monolayer electrolyte cell using BaZr0.8Y0.2O3-δ (BZY20) at 600 °C, assuming hydrogen as fuel under the annual production rate of 50 k/year. However, it was suggested that the system efficiency could be improved to 63 % in case of a lower temperature operation at 550 °C and 69 % adopting a bilayer electrolyte cell at 600 °C. Furthermore, technological options resulted in a system efficiency of 71 % and a production cost of 4,480 USD/system in the case of the bilayer cell, assuming a high-performance cathode when fabricated using the co-sintering method. Finally, the electricity cost was calculated to investigate the system lifetime and fuel cost requirements to achieve the present baseload electricity cost. From an economic and performance perspectives, this study could contribute to the widespread use of PCFC devices by exploring new technological options.