In this paper, the main concern is the designing of microstrip structure for Hyperthermia and tissue heating. The purpose of this antenna designing is the capacity of doing an action in 2.24 GHz Frequency and the usage of Silicone tissue in spite of water bolus to decrease the burn percentage on skin to the least degree and solve the problems caused by the water bolus tissue. The function of the antenna by Moment Method and the frequency analysis method is simulated and developed through several stages and biologic tissue which includes three layers (skin, fat, muscle). The improvement in this antenna is the transformation of heating to the upper part of skin and fat layers. The results have been evaluated in four shapes, water bolus, water bolus—silicon, silicon—water bolus, and silicon alone. In first three shapes, the energy is not capable to permeate into the tissue in higher depths; and, it will stay in the fat tissue. Only when silicon has been used, the energy will permeate into the muscular tissue without any damages to the other body tissues. The size of the antenna (0.84 × 45 × 70 mm) and the coaxial 50 Ω has been used for feeding.
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