Derwent Innovations Index Research Articles

Comparing Patent and Scientific Literature in Airborne Wind Energy

Airborne Wind Energy (AWE) is a renewable energy technology that uses wind power devices rather than traditional wind turbines that take advantage of the kinetic wind energy, and remain in the air due to aerodynamic forces. This article aims to compare the scientific literature with the patents on wind power with tethered airfoils, to obtain better insights into the literature of this area of knowledge. The method used in this study was a comparative bibliometric analysis, using the Web of Science and Derwent Innovations Index databases, and the Network Analysis Interface for Literature Review software and VosViewer. It was possible to verify the main authors, research centers and companies, countries and journals that publish on the subject; the most cited documents; the technological classes; and the networks of collaborations of this work. It was also possible to identify that researches on wind energy with tethered airfoils began their studies in the late 1970s with the first patent apparently dated from 1975 by the inventors Dai and Dai. The first scientific publication was in 1979 by authors Fletcher and Roberts, followed by Loyd in 1980. United States is the country that presented the highest number of patents and scientific papers. Both scientific papers and patents set up networks of collaboration; that is, important authors are interacting with others to establish cooperative partnerships.

Assessing technological developments in amorphous/glassy metallic alloys using patent indicators

Alloys with an amorphous structure represent a class of advanced metallic materials which have great potential for industrial applications and technological innovations as a consequence of their interesting chemical, mechanical and magnetic properties. Considerable effort has been devoted to investigating scientific issues concerning these alloys, but less attention has been paid to assessing the impact of this accumulated knowledge regarding the development of new materials, products and processes. In this study, we evaluated the technological developments in metallic glass using patent indicators. Patent documents are a valuable source of information as they reflect R&D activities and market issues. Data and text mining processing were carried out in order to extract useful indicators from bibliographic records of patent documents indexed in the worldwide Derwent Innovations Index database. The results evaluated the technological advances and showed the life-cycle stage of developments and the interests of companies, research institutions and countries. This study mapped the main alloys and manufacturing processes that have been patented. Amorphous metallic alloys have become ever increasingly important for technological developments regarding metallic alloys in general, and the indicators developed in this study can be used as a source to support decision making in funding new projects and in R&D management.

Needle-like instruments for steering through solid organs: A review of the scientific and patent literature.

High accuracy and precision in reaching target locations inside the human body is necessary for the success of percutaneous procedures, such as tissue sample removal (biopsy), brachytherapy, and localized drug delivery. Flexible steerable needles may allow the surgeon to reach targets deep inside solid organs while avoiding sensitive structures (e.g. blood vessels). This article provides a systematic classification of possible mechanical solutions for three-dimensional steering through solid organs. A scientific and patent literature search of steerable instrument designs was conducted using Scopus and Web of Science Derwent Innovations Index patent database, respectively. First, we distinguished between mechanisms in which deflection is induced by the pre-defined shape of the instrument versus mechanisms in which an actuator changes the deflection angle of the instrument on demand. Second, we distinguished between mechanisms deflecting in one versus two planes. The combination of deflection method and number of deflection planes led to eight logically derived mechanical solutions for three-dimensional steering, of which one was dismissed because it was considered meaningless. Next, we classified the instrument designs retrieved from the scientific and patent literature into the identified solutions. We found papers and patents describing instrument designs for six of the seven solutions. We did not find papers or patents describing instruments that steer in one-plane on-demand via an actuator and in a perpendicular plane with a pre-defined deflection angle via a bevel tip or a pre-curved configuration.

Overview of Flaxseed Patent Applications for the Reduction of Cholesterol Levels.

Flaxseed is becoming an increasingly widely used food ingredient. The rising interest of the food industry in this nutraceutical is primarily because of functional nutrients, such as alpha-linolenic acid and lignans, which have health benefits due to their lipid-lowering properties. The objective of this study was to provide an overview of the patenting of flaxseed products with cholesterol-lowering effects. Patent applications filed by country of origin were retrieved from the Derwent Innovations Index®database. A total of 307 patent documents were identified, of which 184 claim the use of flaxseed or parts of the flax plant in the product formulation, for their lipid-lowering effect when consumed by humans. A few of the patent applications contain claims for new products based on flaxseed in isolation, including the preparation of foods designed to inhibit the production of cholesterol. Most of the claims were for flaxseed in the form of oil and in association with other lipid-lowering compounds, mainly for the food industry, in the form of dietary supplements or baked products designed to raise their high-density lipoprotein content, and for treating heart problems. China and the United States are the leading countries of flax-related applications. These results may have important implications for the production of functional food products that meet specific societal demands.

A SYSTEMATIC REVIEW OF THE LITERATURE RELATING TO CAPTIVE GREAT APE MORBIDITY AND MORTALITY.

Wild bonobos (Pan paniscus), chimpanzees (Pan troglodytes), Western gorillas (Gorilla gorilla), and orangutans (Pongo pygmaeus, Pongo abelii) are threatened with extinction. In order to help maintain a self-sustaining zoo population, clinicians require a sound understanding of the diseases with which they might be presented. To provide an up-to-date perspective on great ape morbidity and mortality, a systematic review of the zoological and veterinary literature of great apes from 1990 to 2014 was conducted. This is the first review of the great ape literature published since 1990 and the first-ever systematic literature review of great ape morbidity and mortality. The following databases were searched for relevant articles: CAB Abstracts, Web of Science Core Collection, BIOSIS Citation Index, BIOSIS Previews, Current Contents Connect, Data Citation Index, Derwent Innovations Index, MEDLINE, SciELO Citation Index, and Zoological Record. A total of 189 articles reporting on the causes of morbidity and mortality among captive great apes were selected and divided into comparative morbidity-mortality studies and case reports-series or single-disease prevalence studies. The content and main findings of the morbidity-mortality studies were reviewed and the main limitations identified. The case reports-case series and single-disease prevalence studies were categorized and coded according to taxa, etiology, and body system. Subsequent analysis allowed the amount of literature coverage afforded to each category to be calculated and the main diseases and disorders reported within the literature to be identified. This review concludes that reports of idiopathic and infectious diseases along with disorders of the cardiovascular, respiratory, and gastrointestinal body systems were particularly prominent within the great ape literature during 1990-2014. However, recent and accurate prevalence figures are lacking and there are flaws in those reviews that do exist. There is therefore a critical need for a robust, widespread, and more up-to-date review of mortality among captive great apes.

A Review of Worldwide Patents: Innovations in Peak Flow Meters for Asthma.

Contemporary healthcare nurses increasingly rely on innovative technology for assessment, treatment, and patient self-management. Funding opportunities as well are increasingly steering toward technology development and innovation. Health researchers, including nursing scientists, who are engaged in medical device innovation need to assess the state of the art of current technology. This requires an intellectual property analysis, or patent search, which is not covered by the types of literature reviews customarily used in health science research. The purposes of this article are to illustrate a methodical review of worldwide patents and to show how those results can be used to identify possible products available for use. An application of peak flow meters for use by patients with asthma is used to illustrate the process. The Derwent Innovations Index interface with keyword searching is illustrated, as is the use of Google Patents. From the 14 patent document results, six possible technologies were identified. The patent search revealed innovations in asthma peak flow meters for use in future research and identified future directions for device development. These results support the claim that patent literature must be included in reviews that seek to identify technology state-of-the-art healthcare applications and that advances in the nursing research paradigm should include patents as background and scholarly products.

Portugues

This paper aims to describe the technological prospecting shooting simulators as well as knowing the number of patents in the world of shooting simulators; understand the main aspects that concern the shooting simulators; and highlight their importance. Therefore, this study was made based on the survey methodology, which was held consultation of patent applications in databases: Derwent Innovations Index®, an online basic patents of Thomson Reuters®, integrated web platform of Knowledge® covering more than 14.3 million inventions, 40 patents emissions of authorities around the world since the year 1963. the results clearly demonstrated the importance of shooting simulators in various segments of society, mainly because of scientific and technological progress that the world stands now.

Disentangling the automotive technology structure: a patent co-citation analysis

While most technological positioning studies were traditionally addressed by comparing firms technological patents classes and portfolios, only a few of them adopted science mapping patent co-citation techniques and none of these seeks to understand the impact of collective cognition on the technology structure of an entire industry. What is the firms technological positioning landscape within an high collective cognition sector? What is the groups technological positioning evolution? How do technology structures shift according to different economic scenarios? Through a strategic lens we contribute to technology strategy literatures by proposing an invention behavior map of automotive actors at a firm, groups and industry level. From Derwent Innovation Index, about 581,000 patents, 1,309,356 citations and 1,287,594 co-citations relationships between (a) the main 49 firms assignees of 1991---2013 and (b) the main 28 or 34 groups assignees by considering three timespan 1991---1997, 1998---2004, 2005---2013, were collected. Results: (1) most of the companies are located close together, depicting the sector technology structure as highly dense; (2) the market leaders do not coincide with technology production leaders and not necessarily occupy central technological positions; (3) the automotive groups considerably varies in the three timespan in terms of position and composition; (4) the market leaders groups occupy technological remoteness positions during economic growth timespan; (5) the sector technology structure is highly dense during growth, strongly scattered and lacking of technologically center positioned actors after economic decline. Finally, strategic implications supporting central locating or suburb R&D positioning planning and M&As recombinational partners decision making are discussed.

Nano/micro-electro mechanical systems: a patent view

Combining both bibliometrics and citation network analysis, this research evaluates the global development of micro-electro mechanical systems (MEMS) research based on the Derwent Innovations Index database. We found that worldwide, the growth trajectory of MEMS patents demonstrates an approximate S shape, with United States, Japan, China, and Korea leading the global MEMS race. Evidenced by Derwent class codes, the technology structure of global MEMS patents remains steady over time. Yet there does exist a national competitiveness component among the top country players. The latecomer China has become the second most prolific country filing MEMS patents, but its patent quality still lags behind the global average.

Bibliometric analysis of research progress in membrane water treatment technology from 1985 to 2013

Research progress in membrane water treatment technology during 1985---2013 was analyzed based on the bibliometric analysis of published papers in ISI Web of Science Core Collection (Science Citation Index-Expanded, SCI-E) database, and patents in Derwent Innovation Index database. The searched data (18,075 SCI papers and 19,182 patents) were statistically analyzed from different time, countries, research institutions, mainstream technologies and application industries. The results indicated that, the number of papers and patents on the membrane water treatment technology showed an increasing trend. The United States and China published the most SCI papers and patents in this field, respectively. China has become one of the major countries in this field, but the research level should be further improved. The research levels of the United States, Germany and France were in the international leading level in this field. Japan published a small quantity of SCI papers, but possessed many patents and ranked in second place. Moreover, the patentees of the top 10 all belonged to Japanese companies or enterprises. The mainstream technologies in the field of membrane water treatment included microfiltration, ultrafiltration, nanofiltration, reverse osmosis, electrodialysis, pervaporation and liquid membrane. Among these technologies, ultrafiltration, reverse osmosis and nanofiltration were the research hotspots in SCI papers, while reverse osmosis and liquid membrane were the research hotspots in patents. These mainstream technologies were mainly used for the treatment of drinking water and desalination of seawater or brackish water, and it is necessary to promote the application of membrane technologies in industrial wastewater treatment.

Phytol a Natural Diterpenoid with Pharmacological Applications on Central Nervous System: A Review.

Phytol (3,7,11,15-tetramethylhexadec-2-en-1-ol), a diterpene member of long and ramified chain of unsaturated acyclic alcohols. The objective of study was to conduct a systematic review of this diterpene and its pharmaceutical applications in Nervous System diseases in humans and/or rodents. Periodicals bases, such as ScienceDirect and PubMed, were used, as well as technological basis of European Patent Office, World Intellectual Property Organization, United States Patent and Trademark Office, Derwent Innovations Index(®), Latin American Bank of Patents and data base of Instituto Nacional de Propriedade Industrial (INPI-National Institute of Industrial Property). The software EndNote-X5 was utilized as reference with the keywords: phytol, anxiolytic, antidepressant and anticonvulsant and their correlations in English, Spanish and Portuguese from January 2003 to June 2014. There are many publications on phytol in international literature. However, there is a reduced number of articles related to pharmacological activities proposed here. In reference to technological bases, patents present a wide range of pharmacological and commercial applications as cosmetics, hypolipodemic, anxiolytic and antidepressant. Therefore, it is necessary to explore phytol molecules, which present high pharmacological potential from scientific and technological points of view, in search of transference of technologies to generate economical and industrial growth.

Current Trends and Future Perspectives in the Development of Denture Adhesives: An Overview Based on Technological Monitoring Process and Systematic Review

Denture adhesives are materials used to enhance denture retention, stability and function. The aim of this study was to systematically review the articles and patents with regard to denture adhesives in order to obtain a scientific and technological overview of this material. A literature search of studies published between 1960 and 2014 was conducted in seven databases: MedLine (PubMed), Web of Science, Lilacs, Ibecs, Cochrane Library, Scielo and Scopus. Additionally, the following patent databases were screened: USPTO, EPO, JPO, INPI, Derwent Innovations Index, Patentscope and Questel Orbit. Data was tabulated and analyzed by Microsoft Office Excel 2013 software and Questel Orbit. A total of 54 articles and 78 patents were included in the analysis. The largest number of patents (n=19) was deposited by Procter and Gamble Company (Cincinnati, Ohio, USA). Furthermore, the most prevalent studies were conducted in vivo (n=30), and the types of adhesive most studied were cream or powder (n=14). It was possible to identify the current scientific and technological scenario of denture adhesives, in which patents filed in many underdeveloped countries were mostly foreignowned. Moreover, the recent advances of such materials have been more related to presentation than to the additional effects of denture adhesives.

Biomedical properties and potentiality of Lippia microphylla Cham. and its essential oils.

Lippia microphylla Cham. (Verbenaceae) is an endemic underexploited Brazilian vegetal. This work reviewed the biological potentialities of Lippia microphylla, emphasizing the properties of essential oils (EOs) and analyzed scientific indicators about genus Lippia and L. microphylla. Databases from 1948 to the present were searched and a software (vantage point 7.1) associated with Derwent Innovation Index was used to identify the indicators of the genus Lippia, and biological activities and compounds in the L. macrophylla species. Ethnopharmacological records report use of L. microphylla leaves to treat gastrointestinal disorders, influenza, bronchitis, cough, nasal congestion, and sinusitis during vaporization, whose aromatic volatile oils are rich in monoterpenes, especially cineole, terpineol, and thymol. Other EOs have larvicidal activity on Aedes aegypti larvae, and antifungal, antibacterial and cytotoxic and antitumor action on human and murine cancer cells. Brazil is the country with more articles about Lippia species, but it deposited only 9 patents since 1993. Most of the publications about L. microphylla are concentrated in food and chemical sciences. This bioprospection helps to choice areas of interest for capital investment and to give support for Brazilian Institutions to establish cooperation and improve technological impact at the point of view of creation and innovation.

Invention profiles and uneven growth in the field of emerging nano-energy

This paper aims to synthetically investigate invention profiles and uneven growth of technological knowledge in the emerging nano-energy field, based on patents data extracted from the Derwent Innovation Index (DII) database during the time period 1991–2012. The trend analysis shows that invention in this field has experienced enormous growth and also diversification over the past 22 years. The co-occurrence network of burst technology domains reveals that technology domains constantly burst, and innovative progress in nanotechnology has tremendously contributed to energy production, storage, conversion and harvesting and so on. Nano-energy patented inventions mainly come from a combinatorial process with a very limited role of developing brand-new technological capabilities. Reusing existing technological capabilities including recombination reuse, recombination creation and single reuse is the primary source of inventions. For the impacts of technology networks' embeddedness, we find that network tie strength suppresses the growth of technological knowledge domains, and network status and convergence both facilitate the growth of technological knowledge domains. We expect that this study will provide some enlightenment for inventing or creating new knowledge in emerging fields in complex technological environment.

Analyzing patent topical information to identify technology pathways and potential opportunities

As a basic knowledge resource, patents play an important role in identifying technology development trends and opportunities, especially for emerging technologies. However patent mining is restricted and even incomplete, because of the obscure descriptions provided in patent text. In this paper, we conduct an empirical study to try out alternative methods with Derwent Innovation Index data. Our case study focuses on nano-enabled drug delivery (NEDD) which is a very active emerging biomedical technology, encompassing several distinct technology spaces. We explore different ways to enhance topical intelligence from patent compilations. We further analyze extracted topical terms to identify potential innovation pathways and technology opportunities in NEDD.

Crystalline Forms of Nonprotein Drugs Filed in Brazil From 1995–2005

In the present study, we evaluated 457 patent applications filed for crystalline forms of nonprotein drugs during the period 1995-2005 in Brazil. Online searches were conducted using the Instituto Nacional da Propriedade Industrial patent database and the Derwent Innovations Index(®). It was found that no patent applications in this area were filed by Brazilian applicants. It was also noted that only 61% of patent applications included the characterization of three or more crystalline phase techniques. In most applications, no determination of purity was provided for chemical and/or crystalline phases. In a subset of patent applications, those for blockbuster drugs, we found that approximately 90% did not meet Instituto Nacional da Propriedade Industrial acceptance criteria nor the criteria developed in this study. These results reveal that appropriate and thorough characterization of the crystalline forms of drugs is, indeed, lacking in patent applications.

Patents in nanotechnology: an analysis using macro-indicators and forecasting curves

In this study, we evaluated future trends of worldwide patenting in nanotechnology and its domains using logistic growth curves while the patent activity from the main countries, technological domains and subdomains were assessed in four different contexts: worldwide, patents filed in the United States Patent and Trademark Office (USPTO), and patents applications in the triadic (TRIAD) and in the tetradic (TETRAD) countries. The indicators were developed based on a set of records recovered from the Derwent Innovation Index database. Nanotechnology has recently emerged as a new research field, with logistic trend behaviors generating interesting discussions since they suggest that technological development in nanotechnology and its domains has reached an initial maturation stage. Future scenarios were compiled due to the difficult to establish upper limits to forecasting curves. Although China's share of patents is small in some cases, it was the only country to constantly increase the number of patents from a worldwide perspective. In contrast, the USA and the EU were the most active in the USPTO, TRIAD and TETRAD cases, followed by Japan and Korea. The technological subdomains of main interest from countries/region changed according to the perspective adopted, even though there was a clear bias towards semiconductors, surface treatments, electrical components, macromolecular chemistry, materials---metallurgy, pharmacy---cosmetics and analysis---measurement---control subdomains. We conclude that monitoring nanotechnology advances should be constantly reviewed in order to confirm the evidence observed and forecasted.

Layout of Nanotechnology Patents in Global Market

Patents are the manifest output of market layout. Based on global nanotechnology patents applied from 1991 to 2010, which are collected by Derwent Innovation Index database, this paper elaborates the distribution and development trends of nanotechnology in global market, through the quantitative analysis of patent distribution in five nanomarkets (materials & process, electronics & devices, biology & medicine, instrument & measurement), in hope of providing an objective statistic reference for future policy directions and academic researches.

Comparative analysis on technologies between Chinese and American large-sized oil companies based on patentometrics

Patent information is critical and important object to reflect differences in technology capacity; the paper makes statistical analysis on structural elements of five large-sized oil companies from America and China as collected in Derwent Innovations Index, and compare technical similarities and differences between such companies' patents with visualization tools, by further research on academic classes, Derwent Class Code and co-occurrence of Manual Code. It is shown from the researches that Chinese enterprises is advantaged in growth in number of patents and cooperation rate, but their patents are characterized by poor influence, less relevance and connection between various disciplines, as well as relatively backward development of patented technology. Finally, according to current status of patents of Chinese and American oil companies, the paper proposes a series of recommendations and countermeasures for improvement in patents quality and future expansion in patented technology by Chinese oil companies.

Natural products against cancer: a comprehensive bibliometric study of the research projects, publications, patents and drugs.

To analyze multi-source data including awards, publications, patents and drugs, and try to draw the whole landscape of the research and development community in the area of natural products (NPs) against cancer. Awards, publications, patents and drugs data from National Institute of Health/Natural Science Foundation of China (NIH/NSFC), PubMed, Derwent Innovation Index and Cortellis were collected. Bibliometric methodologies and technology are used to investigate publications/patents/drugs, their contents and relationships. NIH and NSFC respectively demonstrated a stable and sustained expenditure growth in this area. The number of publications is continuously increasing. Yet the annual patent applications worldwide and FDA drug approvals were little changed or not obviously fluctuated in 2003-2013. USA and several Asia-pacific countries/territories are important contributing powers. We described the evolution of major research topics by those MeSH Major Topics indexed in PubMed with the largest growth range in three intervals, and analyzed hot research topics in the recent 10 years which include NPs or NPs derivatives, cell line/animal model, laboratory technologies and activation mechanisms. China published the most publications and received the most patent applications, but drug discovery performance is no better than USA and Japan. Research on anti-neoplastic structures and compounds originated from Chinese traditional medicine (TCM), medicinal plants, herbal medicine and marine NPs are major research topics in the recent 10 years. There still exits translational gap between basic research and drug discovery. Translational research should be undertaken to strengthen the applicability of NPs.