Mean Depth Research Articles

Clonal haematopoiesis of indeterminate potential predicts recurrence of atrial arrhythmias after surgical ablation for atrial fibrillation

Abstract Background Clonal haematopoiesis of indeterminate potential (CHIP), characterized by the presence of somatic blood cell clone expanding without other haematological abnormalities, was recently shown to be significantly associated with the development and progression of atrial fibrillation (AF). However, the clinical relevance of CHIP in patients underwent surgical atrial ablation remained unexplored. Aims This study investigated the potential role of CHIP in the recurrence of atrial arrhythmias after surgical ablation in patients with AF. Methods Deep-target sequencing of 74 CHIP (a mean depth of coverage = 4051x) was performed in 132 patients with AF (mean age, 60 years; 75.8% male; mean left atrial diameter, 47mm) who underwent surgical ablation without previous atrial ablation between December 2014 and September 2021. Variant allele fraction (VAF) ≥ 2.0% of any targeted genes indicated the presence of CHIP mutations. The primary outcome is the recurrence of any atrial arrhythmias for >30s after a blanking period of 3 months within a year. The clinical significance of CHIP was determined by multivariable Cox proportional hazards regression. Results A total of 17.4% (23 of 132) patients with AF carried CHIP mutations (DNMT3A, 8.3% and TET2, 3.8%). CHIP prevalence varied among AF types, with paroxysmal, persistent, and long-lasting AF counting for 12.5%, 16.5%, and 36.4%, respectively. During one-year follow-up after blanking period, recurrent atrial arrhythmia was documented in 15 (65.2%) and 37 (33.4%) patients in the CHIP and non-CHIP groups, respectively (p = 0.005 for log-rank test). The association of CHIP with atrial arrhythmias recurrence remained significant after fully adjustment (hazard ratio, [95% confidence interval], 1.92 [1.02-3.63]). Conclusions CHIP mutations with a VAF ≥ 2.0% were identified in 17.4% AF patients undertaken surgical ablation and was associated with poor prognosis. CHIP assessment may be useful in the personalized management of patients who planned to perform surgical ablation for AF.

Radioanatomical evaluation of the subtympanic sinus in children under five years old and its clinical implications - high resolution computed tomography study.

This study aimed to evaluate subtympanic sinus (STS) and its vicinity in high-resolution computed tomography (HRCT) scans of children under five years old with non-diseased temporal bones. We divided the whole group into children under 24 months of age (first stage of pneumatisation development) and between 25 and 60 (second stage). We have determined the width of the entrance to STS, depth of the STS, type in relation to facial nerve according to Anschuetz classification, the pneumatisation of posterior and medial air cell tracts, and jugular bulb position. All the HRCTs (280 temporal bones) were analyzed according to the multiplanar reconstruction protocol with symmetrization. STS's mean width and depth were 2.71 ± 0.60mm and 3.26 ± 1.11mm, respectively. The most common STS type was type A (59.3%), followed by type B (30.7%) and type C (10%). The posterior air cell tract (retrofacial cells) was present in 39.3%. The medial air cell tract (hypotympanic cells) was present in 30.7% The jugular bulb position affected the final shape of STS in 17.5%. The results support the necessity of the classification for the STS. Our study may help with surgical planning regarding endoscopic ear procedures and gives a broader understanding of how pneumatization or jugular bulb might correlate with the final shape of the retrotympanum. The historical remarks track the term's origin for clarity in research and respect for earlier investigators.

Impact of Rainfall and Soil Infiltration on Groundwater Dynamics of Yerekoppi-1 Micro-watershed, Haveri District, Karnataka, India

The amount of water infiltrating the soil surface directly affects the quantity of surface runoff and erosion, and the recharge of both soil and groundwater. Groundwater recharge is an informative indicator of the water located beneath the ground surface. It has a direct impact on renewable supplies of groundwater. In the present study on Impact of rainfall and soil infiltration rate was used for effect on the groundwater level of the Yerekoppi-1 micro watershed (Manakur sub-watershed) in Haveri district of Karnataka state. Average annual rainfall is 700.7 mm and mean potential evapotranspiration is 1541.8 mm. An area of about 888 ha (94.32 %) has clay texture at the surface and 53 ha (5.68%) area has contributing settlement. In Yerekoppi-1 micro- watershed, 38 borewells are there in the vicinity of major stream of the micro- watershed. The mean depth of groundwater levels in the micro- watershed were monitored at a monthly frequency during January-2023 to March-2024. It was found that the maximum average depth of bore wells are about 17.6 mbgl and lowest average depth of borewell about 8.8 mbgl. Soil infiltration rate was measured at upper, middle and lower reaches of the watershed area in the year 2023 and 2024. The majority of the area contributed clay soil. In all the areas of micro-watershed, infiltration rate for clay soil is less than 5 mm/hr. Infiltration rates for all the areas was 1.72- 4.78 mm/hr. Soil infiltration during a rainstorm is closely related to a number of factors such as the intensity and kinetic energy of the rainfall, soil surface conditions and soil properties such as those related to aggregate stability. The groundwater recharge may be improved by growing plantation crop for increasing infiltration rate, construction of percolation tanks and farm ponds in the lower most of the agricultural land.

Vision-Based Localization Method for Picking Points in Tea-Harvesting Robots

To address the issue of accurately recognizing and locating picking points for tea-picking robots in unstructured environments, a visual positioning method based on RGB-D information fusion is proposed. First, an improved T-YOLOv8n model is proposed, which improves detection and segmentation performance across multi-scale scenes through network architecture and loss function optimizations. In the far-view test set, the detection accuracy of tea buds reached 80.8%; for the near-view test set, the mAP0.5 values for tea stem detection in bounding boxes and masks reached 93.6% and 93.7%, respectively, showing improvements of 9.1% and 14.1% over the baseline model. Secondly, a layered visual servoing strategy for near and far views was designed, integrating the RealSense depth sensor with robotic arm cooperation. This strategy identifies the region of interest (ROI) of the tea bud in the far view and fuses the stem mask information with depth data to calculate the three-dimensional coordinates of the picking point. The experiments show that this method achieved a picking point localization success rate of 86.4%, with a mean depth measurement error of 1.43 mm. The proposed method improves the accuracy of picking point recognition and reduces depth information fluctuations, providing technical support for the intelligent and rapid picking of premium tea.

Cas9-targeted-based long-read sequencing for genetic screening of RPE65 locus.

Long-read sequencing (LRS) enables accurate structural variant detection and variant phasing. When a molecular diagnosis is suspected, target enrichment can reduce the cost and duration of sequencing. LRS was conducted in five inherited retinal dystrophy (IRD) patients harboring a monoallelic variant in RPE65 that remained uncharacterized after clinical exome sequencing (CES). CRISPR-Cas9 guide RNA probes were designed to target a 31kb region, including the entire RPE65 locus. The DNA was sequenced on a MinION platform. Short-read ×30 whole-genome sequencing (WGS) was performed for five patients to validate nanopore results. The nanopore sequencing process yielded a median of 271 reads within the targeted region, with a mean depth of 109 and a median read size of 8kb. All variants identified by CES have been detected using this approach, and no additional RPE65 gene causative variants were found. Nanopore variant detection demonstrated performance akin to short-read WGS at similar coverage levels, although exhibiting increased false positive calls at lower coverage. In this study, we explore the advantages of using a targeted approach together with long-read sequencing to identify variants associated with IRD. The results underscore the utility of targeted long reads for characterizing patients affected by rare diseases when first-tier diagnostic tests are non-conclusive.

Estimation of skin surface roughness in vivo based on optical coherence tomography combined with convolutional neural network.

The texture of human skin is influenced by both external and internal factors, and changes in wrinkles can most directly reflect the state of the skin. Skin roughness is primarily used to quantify the wrinkle features of the skin. Therefore, effective and accurate quantification of skin roughness is essential in skincare, medical treatment, and product development. This study proposes a method for estimating the skin surface roughness using optical coherence tomography (OCT) combined with a convolutional neural network (CNN). The proposed algorithm is validated through a roughness standard plate. Then, the experimental results revealed that skin surface roughness including arithmetic mean roughness and depth of roughness depends on age and gender. The advantage of the proposed method based on OCT is that it can reduce the effect of the skin surface's natural curvature on roughness. In addition, the method is combined with the epidermal thickness and dermal attenuation coefficient for multi-parameter characterization of skin features. It could be seen as a potential tool for understanding the aging process and developing strategies to maintain and enhance skin health and appearance.

A cephalometric analysis of the antegonial notch in relation to the direction of mandibular growth.

Masticatory muscle forces influence craniofacial morphology development. The antegonial notch (Notch) is a bony concavity on the inferior border of the mandible. Considering the Notch is located anteriorly to the insertion of the masseter muscle and varies among individuals, we hypothesised that these muscles influence the formation of the Notch. Therefore, this study aimed to investigate the correlation between mandible morphology and Notch formation. Sixty Japanese patients who visited the Department of Orthodontics at our university hospital were retrospectively evaluated. Morphological and morphometric analyses of the Notch and related craniofacial parameters were conducted using lateral cephalograms taken at the patients' initial visits. Standard values for the Notch area and depth were determined, and the morphology of the Notch and mandible was analysed using Spearman's rank correlation coefficient (p < 0.05). The mean Notch area and depth was 78.71 ± 36.54 mm2 and 3.11 ± 1.09mm, respectively. The Notch area was significantly correlated with ramus inclination (p = 0.044, r = 0.261) and with the Y-axis (p = 0.039, r = 0.267). This study indicated that both the masticatory muscles and mandibular growth could contribute to the Notch formation.

Effectiveness of Adult Chest Compressions during Resuscitation Performed by Children Aged 10–14 Years under Simulated Conditions

Introduction: Numerous educational programs recommend implementing the teaching principles of BLS from an early age. The aim of this study was to evaluate selected parameters of the quality of resuscitation performed by children aged 10–14 years during simulated circulatory arrest in an adult. Materials and Methods: The project involved four stages, culminating in students performing thoracic compressions on an adult simulator for 2 min. A digital analysis of the quality, depth, relaxation and rate of compressions allowed us to formulate results and conclusions. The authors’ proprietary questionnaire form allowed for the correlation of criteria such as age, gender, body mass and past experience in first aid training of the participant. Results: A total of 149 girls and 130 boys were studied. The mean age was 12 years (SD ± 1.41). A directly proportional increase in body mass with participant age was observed (p &lt; 0.000). Children as young as 10 years old achieved only 24.13% quality, while those at the age of 14 demonstrated a more than doubled value (67.61%). The minimum depth of chest compressions recommended for an adult (5–6 cm) was not reached in any age group. Girls from all grades achieved a mean quality of 44.69% (SD ± 32.57), while boys achieved a score of 60.23% (SD ± 31.74). On the other hand, in the case of evaluating thoracic relaxation, a significantly better result was achieved by girls compared to boys (66.14% vs. 56.78%; rho-Spearman test for p = 0.011). Conclusions: Age, sex and body mass play important roles in the quality of resuscitation provided by children. None of the age groups studied achieved the minimum mean depth during adult thoracic compressions under simulated conditions. It is recommended to modify school-based BLS classes to better match the exercises to students’ predispositions.

The Methods for Estimating Lake Volume, Mean Depth, and Maximum Depth in European Standard EN 16039:2011 Are Flawed and Should Not Be Used

ABSTRACTThe European Standard EN 16039:2011 provides guidelines for assessing lake hydromorphology within the Water Framework Directive and includes methods for estimating volume, mean depth, and maximum depth based on statistical models applied to data from topographic maps. We tested the predictive accuracy of these models using independently collected bathymetric data from 35 Swedish lakes. The models had no predictive power, and the maximum depth predictions were inversely correlated with the observed values. The mean absolute percent error was 46% for volume and mean depth, and 85% for maximum depth. The models are flawed and should not be used.

Adequacy, safety and technical determinants of modified endoscopic ultrasound guided liver biopsy technique in patients with or without cirrhosis : A pilot study

Background and AimsEndoscopic ultrasound-guided liver biopsy (EUS-LB) technique-related factors as a determinant of specimen yield have not been studied. We used a modified technique to study adequacy, safety and technical determinants in patients with or without cirrhosis. MethodsEUS-LB was performed with a 19G Franseen tip needle by wet heparinized suction. One or two passes with a variable number of actuations were taken, the end-point being the aspiration of blood. Primary outcomes were tissue core adequacy and definitive histologic diagnosis. Secondary outcomes were a correlation between the number and depth of actuations with total specimen length (TSL), longest specimen length (LSL) and adverse events (AE). Early and late adverse events (AE) were also accessed. ResultsAdequate samples were seen in 48/50 and histologic diagnosis could be achieved in 49/50 patients. Mean TSL, LSL and depth of actuation were 7.98±3.74cm, 1.89±0.80cm and 4.29±0.98cm, respectively. The median complete portal tracts(CPT) were 23 (range, 7-50) and number of actuations was 7 (range, 4-12) The correlation between TSL with number and depth of actuation was r=0.71 vs 0.53 & r=0.55 vs 0.51 and for LSL were r=0.28 vs 0.11 & r=0.74 vs 0.55 in non-cirrhotic and cirrhotic patients respectively. No major and 7(14%) minor adverse events were observed. ConclusionsThis modified EUS-LB technique results in adequate tissue acquisition and is safe in non-cirrhotic and cirrhotic patients. Technical factors like the number and depth of actuations determine specimen yield.

Capillary rise quantification improves irrigation performance in pear orchards

The shallow water table in Río Negro and Neuquén valley causes a capillary rise (CR) that modifies the water content in soil profile. Therefore, irrigation performance is expected to be affected by the capillary water input into the root zone. The aim of this study was to evaluate the effect of CR on surface irrigation performance during 2020-2021 growing season in a pear orchard. In a Bartlett pear orchard planted in 2003, three irrigation moments were evaluated, and irrigation sheets were calculated to obtain efficiency. Water table level (WTL) was measured monthly in an open aquifer piezometer. CR was calculated with the software UPFLOW. Soil water content was measured with a Frequency Domain Reflectometry (FDR) sensor at: 0.20 m, 0.40 m, and 0.60 m. Water use efficiency (WUE) and water productivity were calculated using pear crop yield and the irrigation sheets applied and the crop water demand, respectively. WTL was shallower in spring than in the rest of the season. The mean depth fluctuated between 0.70-1.20 m during spring, affecting irrigation performance. Data of FDR deepest sensor showed an increase of soil moisture due to CR. Capillary contribution negatively affects irrigation efficiency if it is not included in the water balance. Irrigation schedules can be re-arranged considering soil moisture and CR. In this way, the necessary water sheets could be applied in each crop development stage adjusted to water demand. Improving irrigation performance and WUE enables a sustainable water management strategy in pear production.

Characterization of marine heat waves in the Iberia–Biscay–Ireland (IBI) region in 2022

Abstract. Marine heat waves (MHWs) are defined as prolonged periods of anomalously high sea surface temperatures. These events have a profound impact on marine ecosystems, resulting in ecological and economic impacts such as coral bleaching, reduced surface chlorophyll due to increased surface layer stratification, mass mortality of marine invertebrates due to heat stress, rapid species migrations, and fishery closures or quota changes, among others. This research focuses on the study of the MHWs that occurred in the IBI (Iberia–Biscay–Ireland) region during the year 2022, assessing their climatologic properties, analyzing the mean values for the year 2022, and discretizing the events in four subregions representative of the entire domain. Satellite-derived sea surface temperature data were used to detect and characterize the events, revealing that in some areas the year 2022 showed peak anomaly values of (i) 15 MHW events, (ii) 128 d of mean durations, and (iii) 261 total days of MHWs. Through observational and modeling data, the discrete events located in the Bay of Biscay were also examined in the subsurface layers, demonstrating a strong seasonal modulation and heat diffusion through deeper layers, where cold-season events reach higher MHW mean depth values and subsurface positive anomalies of temperature can remain for weeks once an MHW has ended.

Seni Kaligrafi: Peran dan Kontribusinya Terhadap Pengembangan Peradaban Islam

The art of calligraphy has played an essential role in the history and development of Islamic civilization. The aim of this research is to review the contribution of calligraphy art to the development of culture, religion and science in Islamic civilization. Calligraphy is a form of visual art that is highly valued in the Islamic tradition. Calligraphy not only functions in the field of decoration, but it is also an intermediary in conveying religious messages and moral values. In this research method using historical and textual analysis, researchers found that the art of calligraphy enlarges the intellectual and spiritual life of Muslims, and also becomes an important tool in spreading Islamic teachings. Calligraphy participated in the development of Islamic art and architecture, publishing monumental works that combined aesthetic beauty and depth of religious meaning. This research shows that the art of calligraphy is not only a cultural heritage that must be preserved, but calligraphy also has a sustainable connection in the modern context.

Transvaginal cervical cerclage – How well do surgeons assess their own procedures?

IntroductionIn women with cervical incompetence, transvaginal cerclage may help prevent preterm birth. However, training for this procedure poses challenges due to the low number of cases and difficulties in visualizing the operative field. Furthermore, the objective criteria for a successful cerclage procedure are not well-described. Quality assessment relies heavily on self-assessment rather than objective criteria and feedback. To address this issue, training on a simulator may offer a solution. We aimed to objectively assess surgical performance and compare it to the self-assessed performance in transvaginal cerclage procedures. Materials and methodsDuring the Nordic Federation of Obstetrics and Gynecology (NFOG) congress in 2023, surgeons proficient in transvaginal cerclage procedures performed a transvaginal cerclage on a simulator. To compare the observed and self-assessed outcomes we obtained measurements on the cerclage height and number of bites from the detachable cervix, and from computed tomography scans we analyzed suture bite depth, reduction of cervix surface area, and whether cerclages had perforated the cervical canal. The same outcomes were self-assessed by each participant after the cerclage procedure. We visualized the continuous paired data in a Bland-Altman plot and compared these data with a paired t-test. Paired binary data was analyzed using McNemars test. Results29 participants from eight different nationalities performed one transvaginal cerclage each. The mean height of the cerclage was 26.8 mm (SD 9 mm) and mean depth was 6.5 mm (SD 1.9 mm) across a mean of 4.1 (SD 0.8) bites. The mean reduction of the cervix surface area was 7.6 % (SD 5.9 %). Two sutures perforated the cervical canal. The participants significantly underestimated the height of their cerclage with a mean difference of 6.0 mm (95 % CI 2.1–9.9), (p 0.002), between the observed and the self-assessed height, but otherwise revealed good self-assessment of their performed procedure. ConclusionsOverall, the experienced cerclage surgeons showed a genuine insight into their surgical performance of a transvaginal cerclage. These results could warrant development of a procedural guidelines with objective measures, now reassured that surgeons are capable of self-assessing their procedures.

Spatial Distribution of Groundwater Fluctuation Mapping Using Arc-GIS in Hosur-1 Micro-watershed of Karnataka, India

Groundwater is a primary source of freshwater and used mainly for agriculture and irrigation purposes. Recharge to groundwater is the most important component in all the water balance studies. In the present study krigging technique was used for interpolate the groundwater level of the Hosur-1 micro watershed (Kanakvad sub watershed) in Gadag district of Karnataka state. In Hosur-1 micro- watershed 41 wells are there in the vicinity of major stream of the micro- watershed. The mean depth of ground water levels in the micro- watershed were monitored at a monthly frequency during January-2023 to March-2024. It was found that the maximum average depth of bore wells are about 9.55 mts and lowest average depth of borewell about 4.64 mts. The groundwater table between 2.48 to 14.70 mbgl during summer season period and 3.18 to 21.50 mbgl during the Rabi season. The pH of ground water varied between 7.0-9.0, maximum pH was recorded as 8.9 and minimum was recorded as 7.29 and maximum conductivity &gt;3.82 ds/m and minimum 0.87 ds/m was recorded at Hosur-1 micro-watershed. The average infiltration rate of clay soil 2.73 mm/hr and R2 value for the trend line reaches the value of 0.5876. In case of sandy clay loam average infiltration rate was 3.83 mm/hr and R2 value for the trend line reaches 0.6572. It necessitates continuous monitoring of groundwater for assessing the possible damage on salinity and alkalinity induced soil health.

Comparison of different cementing techniques for cement penetration under tibial component in total knee arthroplasty: a retrospective observational study

PurposeThis study aimed to investigate the differences in cement penetration between cementing techniques in total knee arthroplasty (TKA).Materials and methodsWe retrospectively evaluated knee undergone TKA at our hospital for both preoperative and postoperative computed tomographic (CT) evaluations. Cementing was performed with hand mixing and hand packing (HM group) and with vacuum mixing and cement gun use (VM group). We measured the area under the tibial baseplate (sclerotic and nonsclerotic sides) and compared the mean and maximum depths of cement penetration at each area.ResultsOf the 44 knees evaluated, 20 and 24 knees were in the HM and VM groups, respectively. At the center of the sclerotic side, the mean penetration depths (2.0 ± 0.7 and 2.5 ± 0.7 mm, p = 0.02) and the maximum penetration depths (4.0 ± 0.9 and 5.0 ± 1.6 mm, p = 0.02) were significantly deeper in the VM group than in the HM group. The correlation between preoperative Hounsfield unit values and mean penetration were r = –0.617 (p < 0.01) and –0.373 (p = 0.01) in the HM and VM groups, respectively.ConclusionThe cementing technique of vacuum mixing and using a cement gun allowed for deeper cement penetration compared with the hand mixing and hand packing technique, even in bone sclerotic sites.

Robotic Totally Endoscopic Off-Pump Unroofing of Myocardial Bridge: Early Experience and Midterm Outcomes.

Myocardial bridging (MB) occurs when a coronary artery, commonly the left anterior descending (LAD), has an intramyocardial course. In symptomatic patients who fail medical therapy, surgical unroofing can provide symptomatic relief by improving coronary blood flow. We present a series of patients undergoing robotic totally endoscopic beating-heart MB unroofing. There were 34 patients with an LAD-MB who failed medical therapy and underwent robotic totally endoscopic, off-pump unroofing between January 2017 and October 2023. Patients were evaluated by a multidisciplinary team and underwent provocative coronary angiography to confirm hemodynamic significance. We reviewed perioperative outcomes and contacted patients for midterm follow-up, including completion of a modified Seattle Angina Questionnaire (SAQ). The mean age was 48 ± 8 years, and 56% were female patients. One patient had prior septal myectomy via sternotomy. All patients had significant dobutamine Pd/Pa reduction on preoperative coronary angiography. One patient had atrial fibrillation and underwent concomitant ablation with left atrial appendage ligation. The mean procedure time was 140 ± 69 min. All were completed totally endoscopically off-pump without intraoperative conversions. The mean MB length was 4.5 ± 1.4 cm, and the mean depth was 1.6 ± 0.9 cm. Of the patients, 76% were extubated in the operating room. The mean intensive care unit and hospital length of stay were 0.97 ± 0.58 and 1.73 ± 1.1 days, respectively. There were no mortalities or strokes. There was 1 postoperative take-back for bleeding. At midterm follow-up (19 ± 14 months), 28 patients completed the SAQ; 86% reported "much less angina" during activity compared with before surgery, and 93% reported taking no antianginal medication since surgery. In appropriate patients with hemodynamically significant LAD-MB who fail medical therapy, robotic beating-heart unroofing is possible with good outcomes. Further studies are warranted.

A blended genome and exome sequencing method captures genetic variation in an unbiased, high-quality, and cost-effective manner.

We deployed the Blended Genome Exome (BGE), a DNA library blending approach that generates low pass whole genome (1-4× mean depth) and deep whole exome (30-40× mean depth) data in a single sequencing run. This technology is cost-effective, empowers most genomic discoveries possible with deep whole genome sequencing, and provides an unbiased method to capture the diversity of common SNP variation across the globe. To evaluate this new technology at scale, we applied BGE to sequence >53,000 samples from the Populations Underrepresented in Mental Illness Associations Studies (PUMAS) Project, which included participants across African, African American, and Latin American populations. We evaluated the accuracy of BGE imputed genotypes against raw genotype calls from the Illumina Global Screening Array. All PUMAS cohorts had concordance ≥95% among SNPs with MAF≥1%, and never fell below ≥90% for SNPs with MAF<1%. Furthermore, concordance rates among local ancestries within two recently admixed cohorts were consistent among SNPs with MAF≥1%, with only minor deviations in SNPs with MAF<1%. We also benchmarked the discovery capacity of BGE to access protein-coding copy number variants (CNVs) against deep whole genome data, finding that deletions and duplications spanning at least 3 exons had a positive predicted value of ~90%. Our results demonstrate BGE scalability and efficacy in capturing SNPs, indels, and CNVs in the human genome at 28% of the cost of deep whole-genome sequencing. BGE is poised to enhance access to genomic testing and empower genomic discoveries, particularly in underrepresented populations.

Analisis Puisi “pada suatu Hari Nanti” Karya Sapardi Djoko Damono: Kajian terhadap Jenis Makna dalam Ilmu Semantik

The use of many figurative words makes it difficult for readers to understand the meaning contained in the beautiful stanzas of poetry. The purpose of the research is to analyze semantically with the object of study of a poem entitled "Pada Satu Hari Nanti" written by Sapardi Djoko Damono. This research is studied through semantic analysis to examine the meaning that focuses on analyzing lexical meaning, grammatical meaning, referential meaning, and connotative / figurative meaning. In accordance with the above objectives, the type of research is descriptive qualitative research. Data collection is done using documentation techniques, library techniques, and note-taking techniques. The results of the analysis show that in each stanza of the poem there is a complexity of lexical, referential, grammatical, and connotative/figurative meanings that provide depth and richness of meaning in poetry as well as broader knowledge of the use of language in literary works and how meaning can be interpreted through semantic analysis. The use of many figurative words makes it difficult for readers to understand the meaning contained in the beautiful stanzas of poetry. The purpose of the research is to analyze semantically with the object of study of a poem entitled "Pada Satu Hari Nanti" written by Sapardi Djoko Damono. This research is studied through semantic analysis to examine the meaning that focuses on analyzing lexical meaning, grammatical meaning, referential meaning, and connotative / figurative meaning. In accordance with the above objectives, the type of research is descriptive qualitative research. Data collection is done using documentation techniques, library techniques, and note-taking techniques. The results of the analysis show that in each stanza of the poem there is a complexity of lexical, referential, grammatical, and connotative/figurative meanings that provide depth and richness of meaning in poetry as well as broader knowledge of the use of language in literary works and how meaning can be interpreted through semantic analysis.

EfficientNet Convolutional Neural Network with Gram Matrices Modules for Predicting Sadness Emotion

Images are becoming an attractive area of emotional analysis. Recognising emotions in the images of general nature is gaining more and more research attention. Such emotion recognition is more sophisticated and different from conventional computer tasks. Due to human subjectivity, ambiguous judgments, cultural and personal differences, there is no an unambiguous model for such emotion assessment. In this paper, we have chosen sadness as the main emotion, which has significant impact to the richness of human experience and the depth of personal meaning. The main hypothesis of our research is that by extending the capabilities of convolutional neural networks to integrate both deep and shallow layer feature maps, it is possible to improve the detection of sadness emotion in images. We have suggested integration of the different convolutional layers by taking the learned features from the selected layers and applying a pairwise operation to compute the Gram matrices of feature sub-maps. Our findings show that this approach improves the network’s ability to recognize sadness in the context of binary classification, resulting in a higher emotion recognition accuracy. We experimentally evaluated the proposed network for the stated binary classification problem under different parameters and datasets. The results demonstrate that the improved network achieves improved accuracy as compared to the baseline (EfficientNetV2) and the previous state-of-the-art model.