Levels Of Depressive Symptoms Research Articles

Depressive symptoms' trajectories since adolescence and sleep quality in early adulthood: results from the EPITeen cohort.

We aimed to estimate the association between depressive symptoms' trajectories during adolescence and young adulthood and sleep quality in early adulthood. Data from 802 participants of the EPITeen study, evaluated at 13, 17 and 21 years of age, were analysed. Depressive symptoms were assessed using the Beck Depression Inventory-II and three trajectory classes from adolescence to adulthood were previously identified (High, Moderate, Low). The prevalences of poor sleep quality, overall (score>5) and in its specific dimensions: subjective sleep quality, sleep latency, sleep duration, sleep efficiency, sleep disturbance, use of sleep drugs and daytime dysfunction (score≥2), at 21 years of age were evaluated using the Pittsburgh Sleep Quality Index. Associations were estimated using adjusted odds ratio (OR) and the respective 95 % confidence intervals (CI). At 21 years of age, 29.8 % young adults presented poor sleep quality, which was significantly different between those in the Low and High depressive trajectories (14.3 and 53.1 %, respectively, p<0.001). Compared with participants in the Low trajectory, those in the High trajectory were more likely to present poorer sleep quality at 21 years of age (OR=6.34 95 % CI: 3.94-10.21), particularly worse levels of sleep disturbance (OR=5.89 95 % CI: 2.84-12.21), daytime dysfunction (OR=7.63 95 % CI: 3.63-16.06) and subjective sleep quality (OR=6.61 95 % CI: 3.69-11.85). Poor sleep quality in early adulthood was more frequent among individuals who had high levels of depressive symptoms since adolescence. Monitoring depression until adulthood may help to identify those at higher risk of sleep problems which, in turn, can lead to worse health outcomes over time.

Conspiratorial thinking in a 50-state survey of American adults.

While the NIMH Research Domain Criteria framework stresses understanding how neuropsychiatric phenotypes vary across populations, little is known outside of small clinical cohorts about conspiratorial thoughts as an aspect of cognition. We conducted a 50-state non-probability internet survey conducted in 6 waves between October 6, 2022 and January 29, 2024, with respondents age 18 and older. Respondents completed the American Conspiratorial Thinking Scale (ACTS) and the 9-item Patient Health Questionnaire (PHQ-9). Survey-weighted regression models were used to examine sociodemographic and clinical associations with ACTS score, and associations with vaccination status. Across the 6 survey waves, there were 123,781 unique individuals. After reweighting, a total of 78.6% of respondents somewhat or strongly agreed with at least one conspiratorial idea; 19.0% agreed with all four of them. More conspiratorial thoughts were reported among those age 25 - 54, males, individuals who finished high school but did not start or complete college, those with household income between $25,000 and $50,000 per year, and those who reside in rural areas, as well as those with greater levels of depressive symptoms. Endorsing more conspiratorial thoughts was associated with a significantly lower likelihood of being vaccinated against COVID-19. A substantial proportion of US adults endorsed at least some conspiratorial thinking, which varied widely across population subgroups. The extent of correlation with non-vaccination suggests the importance of considering such thinking in designing public health strategies.

Internalized Heterosexism, Hope, and Depressive Symptoms Among Gay and Bisexual Men

Sexual minority men (SMM), and bisexual men in particular, show elevated risks of depressive symptoms relative to heterosexual men. A breadth of research shows that internalized heterosexism, a primary minority stressor, partially explains the disproportionately high levels of depressive symptoms among SMM. However, it is less clear which factors buffer this relationship. The present study investigated whether hope and its subfactors, agency and pathways, moderated the relationship between internalized heterosexism and depressive symptoms, and whether this was contingent on sexual orientation (gay versus bisexual). An international sample of 412 mostly cisgender gay (59.7%) and bisexual men (40.3%) aged 18–81 years (M = 37.32 years, SD = 14.26) completed the Revised Internalized Homophobia Scale, the Adult Dispositional Hope Scale, and the Center for Epidemiological Studies Depression Scale. Results indicated that internalized heterosexism, hope, agency, and pathways were independently associated with depressive symptoms. Hope, agency, and pathways did not moderate the internalized heterosexism-depressive symptoms relationship, nor were these moderation relationships conditional on sexual orientation. Findings substantiate previous research suggesting that internalized heterosexism is a risk factor for depressive symptoms and hope, agency, and pathways are protective factors. Clinicians working with SMM should consider integrating strategies to mitigate internalized heterosexism and cultivate hope, and scholars should aim to expand research focused on the role of hope in influencing SMM’s mental health outcomes.

B - 13 Effects of Individual and Community-Level Adverse Childhood Experiences and Current Psychopathology among Monolingual Spanish-Speaking Adult Neuropsychology Referrals

Abstract Objective The link between adverse childhood experiences (ACEs) and higher rates of psychopathology in adulthood has been well-established, though far less analogue research has examined this relationship among Latinx patients. This study assessed the relationship between ACEs and symptoms of anxiety, depression, and perceived stress among monolingual Spanish-speaking neuropsychology referrals. Method Data were culled from 27 adult neuropsychology referrals (mean age = 61.70; mean education = 8.59) neuropsychological referrals administered the ACE Questionnaire, Beck Depression Inventory (BDI-II), Geriatric Depression Scale (GDS), Beck Anxiety Inventory (BAI), and Perceived Stress Scale (PSS). Linear regression analyses examined the effect of exposure to individual (e.g., emotional, physical, sexual abuse, neglect, domestic violence) and community-level ACEs on depression, anxiety, and perceived stress symptom endorsement. Results Endorsement of more individual ACEs predicted higher levels of anxiety (R2 = 0.281; p = 0.009) and depression (R2 = 0.127; p = 0.075) symptoms, but not perceived stress levels (R2 = 0.037; p = 0.365. By contrast, endorsement of more community-level ACEs marginally predicted higher anxiety symptoms (R2 = 0.124; p = 0.071), but not depression symptoms (R2 = 0.020; p = 0.568) or perceived stress levels (R2 = 0.045; p = 0.319). Conclusions Experiencing more individual-level ACEs predicted greater anxiety and, to a lesser extent, depressive symptoms, whereas community-level ACEs did not predict similar levels of endorsement of active psychopathology among monolingual Spanish-speaking adults referred for neuropsychological evaluation. Findings emphasize the need of neuropsychologists to consider routinely assessing patient’s childhood trauma history and current psychopathology symptoms during evaluation to improve diagnostic accuracy and recommendations for Latinx patients.

Early childhood education and early childhood special education teachers’ perceived stress, burnout, and depressive symptoms

The current study examines the relationships between teachers’ job demands and resources, perceived stress, job burnout, and depressive symptoms through an online survey administered to early childhood education (ECE: n = 143) and early childhood special education (ECSE: n = 121) teachers in a western state of the United States. Results showed no difference between ECE and ECSE teachers in their levels of job demands, resources, perceived stress, job burnout, and depressive symptoms. Both ECE and ECSE teachers’ job-related stressors were positively related to their perceived stress, and their job commitment was negatively associated with job burnout. However, there were some differences in the correlates of job burnout between ECE and ECSE teachers. For ECE teachers, the number of children with disabilities and their teaching efficacy predicted their job burnout, whereas with ECSE teachers, job-related stressors and the supportiveness of school climate (or the lack thereof) were indirectly related to their job burnout through their perceived stress. The current study suggests that providing professional development for these teachers and enhancing a school’s supportive climate will promote the well-being of both ECE and ECSE teachers.

Understanding depression and anxiety rates of school psychology graduate students.

School psychology graduate students experience many risk factors for problems with mental health, including high workloads, financial distress, and challenging relationships with faculty that can exacerbate feelings of anxiety and depression. Although there have been studies that have investigated depression and anxiety amongst graduate students in general (Eisenberg et al., 2007) and health service psychology students in particular (Hobaica et al., 2021), there are reasons to believe that school psychology graduate students may have different experiences. To date, no research has been found investigating the depression and anxiety symptoms of graduate students in school psychology programs. A survey was sent to 194 school psychology training programs, and 291 graduate students completed it. Approximately one in four graduate students reported moderate to severe levels of depressive symptoms, while one in three reported moderate to severe levels of anxiety symptoms. These symptoms were significantly higher in graduate students identifying as lesbian, gay, bisexual, transgender, queer/questioning, and more identities, women, or reported being from a lower socioeconomic background. There were no differences in depression or anxiety symptoms between the type of program (i.e., doctoral or specialist) or years in program. Implications for trainers of school psychology are discussed. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Depression, Loneliness and Quality of Life in Institutionalised and Non-Institutionalised Older Adults in Portugal: A Cross-Sectional Study.

The World Health Organisation estimates that by 2050, the world's population over 60 will number two billion people, which poses complex challenges in terms of maintaining the mental health of older adults. The COVID-19 pandemic has increased the prevalence of depressive symptoms in this population, but the post-pandemic phase has not yet been studied much. A cross-sectional survey was carried out in 2023 among institutionalised and non-institutionalised older adults (total n = 525; institutionalised = 458; non-institutionalised = 67) who were selected by convenience sampling. The Patient Health Questionnaire (PHQ-9) was used to assess the presence of depressive symptoms, the WHOQOL-BREF to assess perceived quality of life and the Loneliness Scale (UCLA) to assess negative feelings of loneliness. Unconditional logistic regression models were fitted to compute crude adjusted odds ratios (ORs) and the respective 95% confidence intervals (95%CIs) for the association between sociodemographic, clinical and psychosocial characteristics and depressive symptomatology, according to institutionalisation status. The final model was adjusted for sex, age, QoL and feelings of loneliness. Of the 525 participants, 74.6% of the non-institutionalised participants had no or minimal depressive symptoms, while 55.4% of the institutionalised participants fell into this category. Mild to moderately severe depressive symptoms were present in 25.4% of the non-institutionalised participants. 26.9% of the institutionalised participants had mild symptoms, 11.8% had moderate symptoms, 3.9% had moderately severe symptoms, and 2.0% had severe depressive symptoms. Overall, a higher quality of life was associated with lower levels of depressive symptoms. Participants describing feelings of loneliness were more likely also to present depressive symptoms (OR = 78.10; 95%CI 2.90-2106.08 and OR = 3.53; 95%CI 1.72-6.91 for non-institutionalised and institutionalised older adults, respectively), independently of institutionalisation status. The prevalence of depressive symptoms is high in older adults, which means that it has not decreased after the increase seen due to the COVID-19 pandemic. A lower perception of quality of life and the presence of negative feelings of loneliness are associated with the presence of depressive symptoms. These conclusions suggest that plans should be developed to intervene in the dimensions of depressive symptoms, perceived quality of life and negative feelings of loneliness.

Parent-Child Mismatch in Educational Expectations and Depressive Symptoms among Chinese Adolescents.

The roles of both parents' and children's educational expectations in shaping adolescent depressive symptoms have increasingly been discussed, yet in a separate manner. To date, few studies have associated parent-child mismatch in educational expectations with depressive symptoms, and less is known about the variation in the association across gender (male vs. female), educational level (primary vs. secondary), and region status (urban vs. rural) in the Chinese educational setting. Respondents were from a nationally representative sample of adolescent students in China (sample size: 1844; age range: 10-15 years). Parent-child mismatch in educational expectations included three categories: (1) "match", (2) "mismatch-parent higher", and (3) "mismatch-parent lower". Regression analysis with inverse propensity-score weighting was employed to estimate the effect of parent-child mismatch as to educational expectations on depressive symptoms, and stratified analysis was used to examine the variation of the effect by gender, educational level, and region. Compared with the "match" group, the "mismatch-parent higher" group had significantly higher levels of depressive symptoms. Furthermore, the pattern remained consistent between boys and girls, but differed significantly by adolescents' educational level and region status. Specifically, the pattern was more pronounced in the primary school and urban subsamples. Findings in this study indicated that educators and policymakers can develop tailored strategies to alleviate depressive symptoms among the "mismatch-parent higher" group, and especially for those children from primary schools and urban areas.

Typologies of Minority Stressors and Depressive Symptoms among LGBTQ Employees in the Workplace: A Moderated Mediation Model of Workplace Climate and Resilience

Abstract Introduction The pathways between minority stressors and depressive symptoms require a nuanced understanding of how these stressors affect the mental health of sexual and gender minority people. It remains unclear whether minority stressors are associated with depressive symptoms through perception of workplace climate and if resilience moderates these effects. Methods This study examined the direct and indirect effects of different minority stressors (experiences of discrimination, internalized homophobia, expectations of rejection, and concealment of identity) on depressive symptoms through the mediating factor of perception of workplace climate and the moderating factor of resilience. Chinese lesbian, gay, bisexual, trans, and queer (LGBTQ) employees (N = 706) completed a cross-sectional online survey in 2021–2022. We examined the moderated mediating effects using PROCESS macro with a bootstrapping approach. Results Mediation results showed that the four minority stressors were each negatively associated with perceptions of workplace climate, which were associated with higher levels of depressive symptoms among Chinese LGBTQ employees. Moderated mediation models demonstrated that the conditional indirect effects of different types of minority stressors on depressive symptoms through perception of workplace climate were only significant for those with lower levels of resilience. Conclusions Extending the minority stress model to work settings, this study offers new knowledge about the mediating role of perception of workplace climate in the relationship between minority stressors and depressive symptoms. Knowledge about the moderating role of resilience also informs targeted interventions. Policy Implications Interventions targeted at reducing minority stressors, enhancing perceived workplace climate, and promoting resilience are vital to enhance LGBTQ individuals’ mental health.

Effects of pain, hospitalization, and medication on depressive symptom in Syrian patients with chronic diseases

Chronic diseases and pain exacerbate depressive symptom in Syria. Limited research on hospital-induced depressive symptom among Syrian patients with chronic diseases warrants further study. A cross-sectional study in four Damascus hospitals revealed high rates of pain and depressive symptom. This study aims to investigate the prevalence and severity of chronic pain and hospital-induced depressive symptom in Syrian patients, as well as the relationship between pain, depressive symptom, and medication behavior. This study analyzes the impact of pain, hospitalization, and medication on patients with chronic diseases. The four Damascus hospitals included 453 patients from various departments. Data were collected through structured interviews and internationally recognized scales such as the PSEQ, HADS, and MMAS. These findings offer insights into pain management and psychological well-being, with implications for patient care and support strategies. The study involved 453 patients with chronic diseases, with gender distribution showing 46.6% females and 53.4% males. The age range was from 7 to 87 years, with an average of 46.87 years. Chi-square tests revealed a significant connection between gender and HADS-A scores, where 48.3% of females had abnormalities (χ2 (1, N = 453) = 7.125, p = 0.028). Marital status was significantly associated with anxiety and depressive symptom levels, particularly among widowed and divorced patients. Employment status, education, and comorbidity were linked to abnormal HADS-A scores, while education level showed a positive correlation with HADS-D scores. ANOVA tests showed significant differences in MMAS scores across income groups (F (3, 449) = 3.167, p = 0.024), with a notable difference between low-income and lower-middle-income groups (mean difference = 0.389, p = 0.031. Chronic pain and HID are prevalent among Syrian patients with chronic diseases and influenced by socio-demographic factors. Personalized interventions are needed to address psychological symptoms and medication behavior.

Predicting cannabis use moderation among a sample of digital self-help subscribers: A machine learning study

BackgroundFor individuals who wish to reduce their cannabis use without formal help, there are a variety of self-help tools available. Although some are proven to be effective in reducing cannabis use, effect sizes are typically small. More insight into predictors of successful reduction of use among individuals who frequently use cannabis and desire to reduce/quit could help identify factors that contribute to successful cannabis use moderation. MethodsWe analyzed data taken from a randomized controlled trial comparing the effectiveness of the digital cannabis intervention ICan to four online modules of educational information on cannabis. For the current study, we included 253 participants. Success was defined as reducing the grams of cannabis used in the past 7 days at baseline by at least 50 % at 6-month follow-up. To train and evaluate the machine learning models we used a nested k-fold cross-validation procedure. ResultsThe results show that the two models applied had comparable low AUROC values of .61 (Random Forest) and .57 (Logistic Regression). Not identifying oneself as a cannabis user, not using tobacco products, high levels of depressive symptoms, high levels of psychological distress and high initial cannabis use values were the relatively most important predictors for success, although overall the associations were not strong. ConclusionsOur study found only modest prediction accuracy when using machine learning models to predict success among individuals who use cannabis and desire to reduce/quit and show interest in digital self-help tools.

Approach and withdrawal from cognitively effortful activities: Development, validation, and transdiagnostic clinical utility of a cognitive motivation scale

BackgroundDeficits in cognition and motivation predict functioning in depressive and psychotic disorders. However, experimental tasks of cognitive motivation are inconsistently correlated with functioning, time-intensive, and not intuitive in clinical practice. We aimed to develop and validate a self-report instrument to assess motivation processes pertinent to engagement with cognitive activities in daily life. MethodFollowing item generation, scale dimensionality, reliability, and validity were evaluated iteratively over Studies 1–3 with online general adult participants (n1 = 205; n2 = 235; n3 = 181). The 20-item Cognitive Motivation scale was also validated in a Study 3 sub-sample reporting high levels of depressive symptoms (n = 74) and Study 4 early psychosis outpatients (n = 25). ResultsTwo-factor model of cognitive approach and cognitive withdrawal, each with good internal consistency, convergent validity, discriminant validity was supported. Cognitive withdrawal showed stronger associations with cognitive difficulties, depressive symptoms, and functional impairments than traditional motivation scale. Participants reporting high depression levels showed more severe difficulties with cognitive motivation than participants reporting low depression levels. In early psychosis outpatients, correlations with functioning and cognitive effort expenditure provided support for scale validity. LimitationsCross-sectional data collection restricted evaluation of repeated administration psychometric properties. Scale validation was mostly established in online community samples and a small patient sample during the COVID-19 pandemic, thereby limiting generalizability of clinical applications. ConclusionsCognitive Motivation scale is a promising tool for future intervention trials seeking to target motivational processes associated with functioning in the general population and potentially across patient groups with amotivation symptoms.

Depressive symptoms over the final menstrual period: Study of Women's Health Across the Nation (SWAN)

BackgroundWomen may be vulnerable to elevated depressive symptoms during the menopause transition (MT). Studies generally have not considered premenopausal depressive symptom history or examined symptoms in relation to the final menstrual period (FMP). ObjectiveTo identify specific time points in relation to the FMP when depressive symptoms increase or decrease. MethodsParticipants were 1582 multiracial/ethnic women from the longitudinal Study of Women's Health Across the Nation (SWAN). Biological, psychosocial, and depressive symptom data were collected approximately annually. Depressive symptoms were measured by the Center for Epidemiological Studies-Depression (CESD) scale. ResultsWomen with high baseline depressive symptoms (CES-D ≥ 16) declined in symptoms (M = −1.04/yr., 95 % CI = −1.58, −0.50) until 4 years before the FMP, followed by a smaller decrease (M = −0.50/yr., 95 % CI = −0.72, −0.28) until 18 months after the FMP. Depressive symptoms increased (M = 0.21/yr., 95 % CI = 0.11, 0.30) in those with low baseline symptoms until 1 year before the FMP, and decreased (M = −0.06/yr., 95 % CI = −0.11, −0.008) going forward. Greater social support, higher levels of follicle stimulating hormone and estradiol, and less sleep disturbance contributed to greater decline in depressive symptoms among those with high baseline depressive symptoms. Anxiety, experiencing stressful life events, lower body mass index, and poor role-physical function contributed to an increase in depressive symptoms among those with low baseline symptoms. LimitationsExcluded women had higher baseline CES-D scores. Lacked pre-MT depression for pre/early perimenopausal women at baseline. ConclusionAccounting for baseline depressive symptom level and focusing on the FMP more precisely characterize depressive symptom change over the MT.

Work-family conflict and depressive symptoms among working couples: a spillover-crossover process

The study aimed to examine the effect of work-family conflict (WFC) and family-work conflict (FWC) on the level of depressive symptoms among working husbands and wives. First, the study proposed that wife’s WFC influences the husband’s level of depressive symptoms via the mediation of the husband’s FWC. Second, the study predicted that the husband’s WFC leads to the wife’s level of depressive symptoms through the mediation of the wife’s FWC. The study utilized a cross-sectional design that involved 330 teachers and their spouses (N=660) as a study sample. The results show wife’s WFC of strain-based leads to the husband’s depressive symptoms via the husband’s FWC of strain-based. WFC behavior-based of the husband influences the degree of the wife’s depression symptoms via the wife’s behavior-based FWC, whereas WFC time-based of the husband causes the wife to experience depressive symptoms through the wife's FWC. The current findings provide crucial knowledge to the literature as they discover the specific aspects of WFC and FWC that affect individuals’ psychological health.

Psychometric Evaluation of the Traumatic Grief Inventory-Self Report Plus (TGI-SR+) in Chinese Bereaved People.

The Traumatic Grief Inventory-Self Report Plus (TGI-SR+) measures the most recent prolonged grief disorder (PGD) symptom sets defined in the 11th edition of the International Statistical of Diseases and Related Health Problems (ICD-11) and the text revision of the fifth edition of the Diagnostical and Statistical Manual of Mental Disorders (DSM-5-TR). However, the TGI-SR+ has not yet been translated and validated in Chinese. This study aims to evaluate the psychometric properties of the Chinese translation of the TGI-SR+. We examined the Chinese TGI-SR+'s factor structure, internal consistency, convergent validity, discriminant validity, known-groups validity, and optimal clinical cut-off scores in 443 Chinese bereaved adults. Confirmatory factor analyses showed that the two-factor models showed the best fit for the Chinese TGI-SR+ items assessing ICD-11 and DSM-5-TR prolonged grief symptoms. Items assessing ICD-11 and DSM-5-TR prolonged grief symptoms demonstrated good internal consistency. Associations of TGI-SR+ scores with symptom levels of prolonged grief (assessed by the International Prolonged Grief Disorder Scale), posttraumatic stress, anxiety, and depression supported convergent and discriminant validity. Associations with background/loss-related variables provided evidence for known-groups validity. Cut-off points for probable ICD-11 PGD (liberal scoring rule), probable ICD-11 PGD (conservative scoring rule), and probable DSM-5-TR PGD were ≥67, ≥75, and ≥68, respectively. The Chinese TGI-SR+ appears to be a reliable and valid measure to assess prolonged grief symptoms per ICD-11 and DSM-5-TR among Chinese bereaved adults.

Emotions observed during sessions of dialectical behavior therapy predict outcome for borderline personality disorder.

We examined whether the emotions that clients experience within session are associated with treatment outcome in dialectical behavior therapy (DBT) for borderline personality disorder (BPD). Participants were 52 adults who met criteria for BPD and were enrolled in a 12-month DBT treatment. The Classification of Affective-Meaning States, an observer-rated measure of discrete emotions, was used to code videos of individual DBT sessions. Raters coded three psychotherapy sessions for each participant: one session from each of the early, working, and late phases of psychotherapy. Self-report measures of BPD symptoms were used to assess treatment outcome. More emotional experience overall during the early phase predicted fewer BPD symptoms at 12-month treatment outcome, explaining 19% of the variance in symptoms. However, increases across treatment in global distress predicted higher levels of BPD (24% of the variance explained) and depression symptoms (15% explained) at termination. Increases in emotional flexibility (i.e., variation between states) from the early to working phase predicted fewer depressive symptoms at termination (14% explained). Self-compassion coded during the working phase also predicted a better treatment outcome (explaining 19%-34%). Clients' in-session emotional experiences predict treatment outcome 8-10 months later. Clients with BPD may benefit from more overall exploration of their emotional experiences early in DBT, as well as expression of self-compassion. Increases in nonspecific, intense negative affect anticipates poor prognosis, whereas increases in emotional flexibility during early treatment anticipates better prognosis. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Cognitive functioning in adults with chronic insomnia disorder- A cross-sectional study.

Chronic insomnia, affecting 15.9% of the population, is characterized by sustained hyperarousal and heightened somatic, cognitive, and cortical activity. Despite its prevalence, the precise impact of chronic insomnia on cognitive domains, particularly attention, working memory, and executive function, remains inadequately understood. This study aims to systematically investigate the cognitive functioning of adults with chronic insomnia. A meticulously matched cohort of 80 participants, comprising 40 with chronic insomnia and 40 controls, participated in this cross-sectional study. The diagnosis followed strict criteria outlined in the International Classification of Sleep Disorders-3. Neuropsychological assessments, including the Digit Span Test, Stroop Test, and Trail Making Test, were employed to scrutinize attention, working memory, and executive function. Robust metrics, such as the Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), Generalized Anxiety Disorder-7 (GAD-7), and Patient Health Questionnaire-9 (PHQ-9), supported the investigative approach. Analysis revealed notable deficits in backward digit span, digit symbol substitution test, and Stroop Test (cards B and C) among chronic insomnia subjects compared to non-insomniac counterparts. Trail Making Test B indicated prolonged completion times in the chronic insomnia cohort. Despite comparable levels of anxiety and depressive symptoms, the chronic insomnia group exhibited higher ISI and PSQI scores, indicating the severity of their sleep disturbances. This cross-sectional analysis reveals cognitive deficits associated with chronic insomnia, specifically impacting attention, working memory, and executive function. Even with meticulous demographic controls, chronic insomnia leaves a discernible impact on cognitive functions. The study underscores the need for precise cognitive evaluations to reveal the latent impact of chronic insomnia, offering insights for targeted interventions.

Depression symptoms among Afghan TB patients: A multi-center study

BackgroundDepression in TB patients carries a heightened risk of treatment failure and a lower quality of life. However, no study to date has documented depression prevalence among TB patients in Afghanistan. ObjectivesWe aimed to assess depression prevalence in TB patients in Southern Afghanistan. MethodsBetween February 2023 and May 2024, a sample of 1,003 TB patients aged 18 years and above were randomly sampled in Southern Afghanistan. The questionnaire gathered patients’ sociodemographic information, clinical characteristics, social support level, and the PHQ-9 (Patient Health Questionnaire). We fitted a binary logistic regression model to identify correlates of depression symptoms among TB patients. ResultsOut of 1,003 patients, 69.6% (95% CI: 66.6%-72.4) had depression symptoms. We found that patients with no formal education [AOR = 3.18, 95%CI (2.35–4.30)], those with severe disease [1.84 (1.30–2.59)], patients with medical comorbidity [1.88 (1.29–2.74)], and those with low social support [1.69 (1.22–2.33)] were more likely to have depression symptoms. ConclusionTB patients in Afghanistan have high levels of depressive symptoms. Therefore, this study advocates for dedicated mental health screening and counseling services for TB patients in Afghanistan.

Higher caloric ratio of carbohydrate intake associated with increased risk of depression: A cross-sectional analysis of NHANES data from 2005 to 2020

IntroductionDepression remains a significant global mental health challenge. However, the relationship between the Caloric Ratio of Carbohydrate Intake (CRC) and depression remains unclear. MethodsThis study utilizes data from the NHANES database spanning 2005–2020 and employs R programming language for data analysis. Depression was assessed using the Patient Health Questionnaire-9 (PHQ-9). CRC was calculated as total carbohydrate intake*4/total caloric intake. Multivariable logistic regression models and regression spline models were applied to further explore the relationship between CRC and Depression. ResultsData from 9254 participants were included, with 1530 individuals identified with depression. A higher CRC, exceeding 54.1 % (Quartile 4 (Q4) of the population), was associated with higher levels of depressive symptoms. Adjusted multivariable logistic regression models indicated a higher depression level (β = 0.5102, 95%CI [0.2419–0.7784], P = 0.0002), higher risk of depression (HR = 1.3380, 95 % CI [1.1331–1.5812], P = 0.0006) and higher impact of depression on life (HR = 1.5133, 95 % CI [1.1656–1.9746], P = 0.0020) at CRC-Q4 levels compared to Quartile 1 (Q1) of the population levels. ConclusionIn this extensive cross-sectional study, our findings suggest that a higher CRC is significantly associated with an increased likelihood of depressive symptoms among U.S. adults.

The association between depressive symptoms and overweight or obesity in prepubertal children: Findings from the QUALITY cohort

BackgroundYouth obesity and depression are public health concerns. Although meta-analyses suggest a positive association between those conditions in adults and adolescents, evidence remains unclear in prepubertal children. We examined the bidirectional associations between levels of depressive symptoms and weight status in 8–10-year-old children with a parental history of obesity, over two years, and whether they differ by sex. Methods: Data were drawn from the QUebec Adipose and Lifestyle InvesTigation in Youth Cohort Study's baseline and first follow-up evaluations (n = 558). Depressive symptoms were assessed using the 12-item Center for Epidemiological Studies Depression scale and weight status using body mass index z-scores based on World Health Organization standards. Linear and logistic regression models were used to test the directionality and magnitude of the associations, adjusting for age, sex, physical activity, screen time, parental education, alcohol and cigarette use, and baseline outcome measure. Results: Children with higher levels of depressive symptoms at baseline were not more likely to have overweight/obesity at follow-up (odds ratio [95 % Coefficient Interval] = 0.95[0.88;1.02]). Baseline overweight/obesity was not associated with subsequent higher levels of depressive symptoms (beta coefficient [95 % Coefficient Interval] = 0.20 [−0.47;0.87]). No sex differences emerged. Limitations: Selection bias may have occurred due to loss at follow-up (10 % attrition) and exclusion of 6 participants taking mood disorder medication. Conclusions: Unlike in adults and adolescents, no association between weight status and depressive symptoms was observed in childhood over two years. Underlying mechanisms linking both conditions later in life may not apply as early as prepubertal childhood.