Depressed Persons Research Articles

Optimal control strategies for taming TikTok addiction: a mathematical model and analysis

Abstract Optimal control theory is an extension of the calculus of variations. It is a mathematical optimization method for deriving control strategies for a dynamic system. In this paper, the system of differential equations for which we aim to utilize control theory is TikTok, which is one of the most attractive internet platforms. TikTok has garnered immense popularity, surpassing other social media platforms. However, its addictive nature has raised concerns about mental health, including depression, eating disorders, anxiety, self-obsession, and narcissistic personality disorder among its users. This paper introduces a mathematical model for TikTok, considering the usage of this app as an epidemic. The model is rigorously validated through stability analysis of both local and global equilibrium. Moreover, disease-free and non-trivial equilibrium scenarios are discussed by calculating their reproduction numbers. This study aims to raise awareness of TikTok’s potential misuse and explore control theory solutions to mitigate addiction. Additionally, statistical data is used to visualize the numerical results and analyze the impact of control parameters on the TikTok model.

Depression in adolescence and young adulthood: the difficulty to integrate motivational/emotional systems.

Depression is presented as a multi-factorial bio-psycho-social expression that has evolved primarily as an effect of stressors related to the motivational/emotional systems that regulate the BrainMind in our relationship with conspecifics. These stressors may be caused by two sources of threat, firstly, the loss of bonding with the caregiver and later with a partner and/or group which relates to the SEPARATION (PANIC/GRIEF) system, secondly, social defeat as an expression of the social competition and social dominance. The sexual maturity drives the individual to social competition and social dominance, even if the latter often occurs before sexual maturity, e.g., chickens, dogs, non-human primates, and humans. Depression is an evolutionarily conserved mechanism in mammals to terminate both separation anxiety, so as to protect the vulnerable social brain from the consequences of prolonged separation anxiety, and the stress of social competition when social defeat is predictable. Adolescence and Young adulthood are particularly susceptible to these two types of threat because of human developmental characteristics that are summarized by the term neoteny. This refers to the slowing down of growth and development, resulting in both a prolonged period of dependence on a caring/protective adult and the persistence of juvenile characteristics throughout life. Therefore, neoteny makes the transition from childhood to sexual maturity more dramatic, making the integration of the SEPARATION (PANIC/GRIEF) system with the dynamics of social competition and dominance more stressful and a source of depression. Stress is an expression of the HPA-Hypothalamic-Pituitary-Adrenal axis that articulates with other systems, mainly the autonomic nervous system and the immune-inflammatory system. The latter is believed to be one of the most significant components in the dynamics of depressive processes, connected to the prodromes of its activation in childhood, under the pressure of environmental and relational stressors which can lead to learned helplessness. The recurrence of stressors makes it easier for the immune-inflammatory system to be activated in later life, which could make a significant contribution to the establishment of a depressive disease. The possible contribution of children's identification processes with their parents' depressive personalities through observational learning is considered.

Prosody-focused feedback enhances the efficacy of anti-depressive self-statements in depressed individuals - A randomized controlled trial.

This study was aimed to evaluate whether the efficacy of invoking anti-depressive self-statements to cope with depressed mood can be enhanced for depressed individuals by systematically guiding them to amplify the expression of conviction in their voice. Accordingly, we recruited N=144 participants (48 clinically depressed individuals, 48 sub-clinically depressed individuals, and 48 non-depressed individuals). Participants were randomly assigned to an experimental or control condition. Across study conditions, participants completed a mood induction procedure, then read aloud scripted anti-depressive self-statements designed to reduce depressed mood. Participants in the experimental condition received instructions to heighten the prosodic expression of conviction in their voice; participants in the control condition received no prosodic expression instructions. Results showed that depressed participants achieved a more pronounced decrease of depressed mood in the experimental condition than in the control condition. Further, the results indicated no effects in sub-clinically depressed and non-depressed individuals. Finally, heightened conviction expressed by participants in the experimental condition was associated with lower depressed mood and diminished depressive symptom severity. Overall, our findings suggest that fostering the prosodic expression of conviction in depressed persons' voices, while they vocalize anti-depressive self-statements, represents a promising method for augmenting the efficacy of cognitive interventions for depression.

Transference-focused psychotherapy for treatment-resistant depression and comorbid personality disorders.

Transference-focused psychotherapy for treatment-resistant depression and comorbid personality disorders.

Neural processing of sad and happy autobiographical memories in women with depression and borderline personality disorder

Patients with major depressive disorder (MDD) and borderline personality disorder (BPD) are reported to have disrupted autobiographical memory (AM). Using functional magnetic resonance imaging we investigated behavioral and neural processing of the recall of emotional (sad and happy) memories in 30 MDD, 18 BPD, and 34 healthy control (HC) unmedicated women. The behavioral results showed that the MDD group experienced more sadness than the HC after the sad recall, while BPD participants experienced less happiness than HC after the happy recall. The fMRI results for sad AMs, compared to happy AMs, elicited greater activation in multiple brain regions (i.e., medial prefrontal cortex, posterior cingulate cortex, insula) linked to self-related information, emotional processing, and semantic recollection across all groups. Functional connectivity analysis revealed a significant main effect of group between the occipital cortex and precuneus and between occipital cortex and posterior cingulate cortex. The effect was driven by stronger connectivity between the occipital cortex and precuneus in the clinical groups taken together than in the HC. Our results suggest a need for stronger coordination between visual imagery and contextual recall for vivid memory retrieval in these clinical groups.

Beyond Cumulative Scores: Distinct Patterns of Adverse Childhood Experiences and Their Differential Impact on Emotion, Borderline Personality Traits, and Executive Function.

Adverse childhood experiences (ACEs) are associated with long-lasting and multifaceted consequences for mental health. Despite established dose-response effects of ACEs on mental health, the specificity of ACE pattern effects remains understudied, especially on executive function. This study aims to explore how specific patterns of ACEs, beyond just cumulative scores, differentially impact emotional symptoms, personality and cognitive function. This study recruited 2515 college students from several universities in northern China. Demographic characteristics, depression, anxiety, borderline personality traits, and executive function (Wisconsin Card Sort Test) were assessed. Latent class analysis was used to identify patterns of ACEs. Data were analysed using χ2-test, ANCOVA, and multivariate linear regression methods. Pattern-oriented and cumulative-oriented approaches were compared to predict the effects of ACEs. Three distinct patterns of ACEs were identified: low adversity (LA), multiple adversity (MA), and family environment adversity (FA). FA with the highest number of ACEs was uniquely linked to executive function impairments, while both MA and cumulative ACEs significantly predicted higher anxiety, depression, and borderline personality traits. The pattern-oriented method was more sensitive to capturing the diverse outcomes of executive function impairment than cumulative scores. Our findings highlight the importance of moving beyond cumulative scores and considering specific ACEs patterns to understand their differential impact on mental health. Identifying FA as a distinct pattern with specific consequences for executive function offers valuable insights into developing targeted prevention strategies tailored to specific risk profiles.

Impact of Body Image Perception on Behavioral Outcomes in Chinese Adolescent and Young Adult Survivors of Sarcoma.

To identify the prevalence and predictive factors of body image dissatisfaction among Chinese adolescent and young adult (AYA) survivors of sarcoma and to evaluate its associations with behavioral outcomes. In total, 116 AYA survivors (response rate: 88%; 48.3% female; mean age 28.2 years, SD = 8.2 years) of osteosarcoma (49.1%) or soft-tissue sarcoma (50.9%) were recruited from an academic hospital. The survivors self-reported their perceived body image using the Body Image Scale. Behavioral outcomes were assessed using DSM-oriented scales of the ASEBA Adult Self-Report checklist. Multivariable linear regression was conducted to identify predictors of body image perception and to investigate the association between body image dissatisfaction and behavioral outcomes (adjusted for clinically relevant variables and corrected for false discovery rate). Mediation analyses were performed to examine the mediating effects of body image perception between clinical, treatment, or socioenvironmental risk factors and behavioral outcomes. At 15 years post-cancer diagnosis, one-third of the cohort (39.7%) reported dissatisfaction with their body image. The significant risk factors associated with body image dissatisfaction were being female (standardized coefficient estimate [Est] = 0.21, SE = 0.10; p = 0.047), surgery treatment (Est = 0.19, SE = 0.09; p = 0.046), and worse family functioning (Est = 0.27, SE = 0.10, p = 0.013). Body image dissatisfaction was associated with symptoms of depression (Est = 0.30, SE = 0.10; p = 0.005) and avoidant personality problems (Est = 0.37, SE = 0.11; p < 0.001). Negative body image perception significantly mediated the association between poor family functioning and avoidant personality problems (proportion-mediated 26.3%, p = 0.038). Body image dissatisfaction was associated with more significant internalizing symptoms of depression, anxiety, and avoidant personality. A negative body image perception may mediate the association between poor family functioning and psychological distress among adult survivors. The provision of psychosocial intervention early during the cancer care continuum may mitigate the negative impact of body image distress in Chinese AYA survivors.

Anhedonia in flux: Understanding the associations of emotion regulation and anxiety with anhedonia dynamics in a sample with major depressive disorder

Negative rumination and emotion regulation difficulties have been consistently linked with depression. Despite anhedonia—the lack of interest in pleasurable experiences—being a cardinal symptom of depression, emotion regulation of positive emotions, including dampening, are considered far less in the literature. Given that anhedonia may manifest through blunted responses to previously positive or enjoyable experiences, it is vital to understand how different positive emotion regulation strategies impact anhedonia symptom severity and how it can vary or change over time. Moreover, understanding the detrimental or protective nature of positive emotion regulation on anhedonia can aid with future anhedonia-focused treatments. Therefore, the current study examined the temporal association between anhedonia dynamics and two different emotion rumination strategies in response to positive emotions: dampening and positive rumination. Depressed persons (N = 137) completed baseline measures of positive emotion regulation, difficulties regulating negative emotions, and anxiety, and completed ecological momentary assessments three times per day for 90 days regarding their depressive symptoms, including anhedonia. We assessed baseline dampening and amplifying scores to predict anhedonia dynamics through four linear models with interactions. Providing partial support for our hypotheses, results indicate that amplifying positivity is positively associated with fluctuations, instability, and acute changes in anhedonia over the course of 90 days; however, neither dampening, difficulties regulating negative emotions, nor anxiety were related to anhedonia dynamics. The current findings suggest that amplifying positivity may be able to predict changes in anhedonia over time and should further be examined as a potential protective factor of anhedonia.

Staff Observational Differences Between Depressive Disorders and Personality Disorders.

Distinguishing those with a personality disorder from those with major depressive disorder (MDD) can be challenging, but establishing the correct diagnosis can direct appropriate management. To identify whether behavioural themes differ between those with personality disorders from those with MDD, and how those differences might relate to a clinical team's perception of diagnosis. An observational study identifying all inpatients presenting with symptoms of depression. At discharge, patients (n = 60) underwent a structured diagnostic interview and were grouped according to diagnosis. Qualitative data was analysed to determine whether behavioural themes differed between those with MDD and those with a personality disorder (with or without MDD). Ward staff perceptions of diagnosis aligned in all cases of personality disorder, but they also attributed that diagnosis to 54% of patients who had only MDD. Several behavioural themes were evident in those with a personality disorder but not those with MDD. Many behavioural themes were observed in both groups, and it is likely these that drove differences in diagnostic views. Certain behavioural themes may be determinants of the perception of diagnosis held by inpatient staff, and when present in acute episodes in MDD, may risk diagnostic misattribution.

Understanding the Effectiveness of Cognitive Behavioural Therapy: A Study on Offenders.

Cognitive behavioural therapy (CBT) is well known for its effectiveness in addressing psychiatric disorders such as depression, anxiety, PTSD, and borderline personality disorder, often used alongside medication. CBT is used more often in the criminal justice system to help rehabilitate offenders by targeting cognitive distortions affecting their social and decision-making abilities. These maladaptive behaviours and sense of entitlement can result from distortions, which CBT works to address by restructuring thought patterns and encouraging adaptive behaviours. In general, CBT is a crucial method for decreasing repeat offences and dealing with mental health problems within the legal system. CBT has demonstrated encouraging outcomes in decreasing reoffending rates in both youths and adults, aiding criminals in acquiring abilities to successfully re-enter society. Although it has replaced traditional rehabilitative services such as education and occupational therapy, its success highlights its importance in offender rehabilitation programmes. Nevertheless, inmates are frequently required to participate, causing doubts about their willingness to engage voluntarily.

The Predictive Role of Personality Disorders and Personality Traits in Death Anxiety.

The current study investigates the interplay between personality traits, personality disorders, and death anxiety in a sample of 2331 participants (49% males; 51% females) across two phases. The Death Anxiety Scale, the Psychosocial Personality Inventory, and the Personality Diagnostic Questionnaire were utilized. The findings revealed significant predictive relationships between personality disorders and death anxiety. Positive correlations were observed between death anxiety and nine personality disorders, including avoidant (r = .227), borderline (r = .123), dependent (r = .157), depressive (r = .098), histrionic (r = .074), narcissistic (r = .111), negativistic (r = .103), obsessive-compulsive (r = .126), and schizotypal (r = .078) personality disorders (p < .001). Death anxiety had significant inverse correlations with leadership (r = -.101) and spirituality (r = -.099) traits (p < .005). Avoidant personality disorder projected the highest prediction for death anxiety (β = .227; p = .000). Leadership as a personality trait demonstrated an outstanding ability to prevent death anxiety (β = -.101; p = .013). These findings make a unique contribution to the literature of death anxiety, personality disorders, and personality traits.

Six-year course over time and predictors of suicidal ideation in depressed older patients

BackgroundIt is important to know predictors of long-term course over time of suicidal thoughts and ideation in depressed older persons. MethodsIn this study, 378 depressed older persons were interviewed at baseline, and after 2 and 6 years to evaluate the presence of depressive disorder. The Inventory of Depressive Symptomatology (IDS) was administered every 6 months for 6 years. Latent Class Growth Analysis was performed on the IDS item on suicidal ideation to identify subgroups with different trajectories. ResultsFive subgroups with suicidal ideation trajectories were identified: 1) severe, transient (10.9 %), 2) severe, persisting (8.0 %), 3) mild, but increasing (14.9 %), 4) moderate, persisting (35.6 %), and 5) no thoughts (30.6 %). Mixed model analysis showed that trajectories were related to 6-year course of depressive symptoms. Yet, suicidal ideation or thoughts of loss of meaning of life were still present in 22.7 % and 17.4 % of those who remitted after 2 and 6 years. Independent of baseline depressive symptom severity, loneliness, childhood trauma, history of suicidal ideation or attempt, openness to experience, earlier age of depression onset, anxiety symptom severity and worse mastery predicted worse trajectories. Limitations47 % dropped out at 6-years follow-up, we did not distinguish between thoughts of death and suicide, we did not assess death by suicide. ConclusionsAlthough trajectories of suicidal ideation and thoughts of loss of meaning of life were strongly related to the course of depression severity, they also appear after remission. Clinicians should be vigilant for suicidal ideation or death wish, even after remission of depression.

Factors Influencing Depressive Symptoms in the Post-COVID-19 Pandemic Period.

Background Mental health issues associated with the COVID-19 pandemic have been widely reported, with various influencing factors identified. However, factors affecting mental health in the post-pandemic period remain unclear. Therefore, this study aimed to investigate the factors influencing depressive symptoms during the COVID-19 post-pandemic period. Methods An online cross-sectional survey using convenience sampling was conducted from December 5, 2023 to December 8, 2023. Basic demographic information and social factors were evaluated using a custom-designed questionnaire. Depressive symptoms were measured with the Japanese version of the Hospital Anxiety and Depression Scale, personality traits were measured with the Japanese version of the Ten Item Personality Inventory, and stress coping strategies were measured with the Japanese version of the Brief Coping Orientation to Problems Experienced Inventory. Logistic regression analysis was performed to examine the impact of gender, age, occupation, subjective economic status, COVID-19 history, presence of pre-pandemic depressive symptoms, personality traits, and stress coping strategies on post-pandemic depressive symptoms by calculating ORs and CIs. All statistical analyses were performed using IBM SPSS Statistics for Windows, Version 29.0 (Released 2022; IBM Corp., Armonk, NY, USA). We set a statistical significance level of 0.05 (two-tailed). Results Among all participants (n = 838), lower subjective economic status (OR: 2.90, 95% CI: 1.99-4.24), frequent substance use (OR: 1.70, 95% CI: 1.17-2.46), higher self-blame (OR: 2.03, 95% CI: 1.39-2.95), higher levels of active coping (OR: 0.58, 95% CI: 0.38-0.88), higher acceptance (OR: 0.61, 95% CI: 0.38-0.98), and pre-pandemic depressive symptoms (OR: 16.84, 95% CI: 11.61-24.44) were significantly associated with post-pandemic depressive symptoms. Conclusions This study identified pre-pandemic depressive symptoms, lower subjective economic status, higher self-blame, and frequent substance use as risk factors for post-pandemic depressive symptoms. These findings suggest the need for social support, economic assistance, and mental health education to promote constructive stress management alternatives to substance use for the prevention of depression in the context of pandemics.

Concepts of Mental Disorders Among Psychiatrists, Psychologists, and Theologians.

The objective of this study was to compare the perspectives of psychiatrists, psychologists, and theologians on schizophrenia, depression, anxiety, and antisocial personality disorder. A cross-sectional research design was utilized, involving a random sample selected from the official registries of these professionals. The findings revealed significant differences in how these groups conceptualize mental disorders. The preferred concepts varied depending on the specific disorder. For instance, when it came to schizophrenia, psychiatrists showed a greater inclination towards the psychodynamic concept compared to psychologists, who leaned more towards the cognitive and social constructivist concepts. In the case of depression, psychiatrists favored biological, psychodynamic, and spiritual concepts, while psychologists tended to prefer the cognitive concept. Theologians consistently favored the spiritual concept across all four diagnoses, in comparison to both psychiatrists and psychologists. This research holds significant value for both theoretical understanding and practical applications, and future studies should consider incorporating qualitative, in-depth research to explore the complexities of these concepts related to mental disorders.

Investigation of Body Perception, Alexithymic Characteristics, and Self-Esteem in Patients Underwent Septorhinoplasty.

Objective: This study evaluated patients' body perception, self-esteem, and personality traits during the preoperative and postoperative periods of septorhinoplasty. Based on these evaluations, we may provide patient selection recommendations for septorhinoplasty applicants. Methods: In this cross-sectional questionnaire study, 86 patients who underwent primary septorhinoplasty in the Department of Otolaryngology at Bilecik Training and Research Hospital were included between March 2023 and 2024. The same surgeon performed all operations. The preoperative Rhinoplasty Outcome Evaluation (ROE) Questionnaire, Rosenberg Self-Esteem Scale (RSES), Body Perception Scale (BPS), Toronto Alexithymia Scale (TAS), and TEMPS-A Temperament Scale in the preoperative period and ROE, RSES, and BPS in the postoperative period were applied. Results: Fifty-four female and 32 male patients participated in our study. The mean age was 24.0 ± 0.6 years. While there was no significant difference in the BPS and RSES scores between the preoperative and postoperative periods, the total ROE score was significantly higher in the postoperative than in the preoperative period. Postoperative ROE scores were positively correlated with RSES and hyperthymic temperament. In contrast, it was negatively correlated with depressive temperament, cyclothymic temperament, anxious temperament, BPS total score, TAS total score, and TAS emotion recognition and expression subscale scores. In the group with alexithymia features separated according to the TAS cutoff score, preoperative and postoperative ROE results were significantly lower, whereas depressive, cyclothymic, irritable, and anxious personality traits and total BPS scores were higher. However, the postoperative RSBE scores were lower in this group. Conclusion: This is the first study to evaluate self-esteem, body image, alexithymia, and personality traits in septorhinoplasty patients. Appropriate patient selection is essential for success and patient satisfaction in aesthetic operations such as septorhinoplasty. Performing BPS, TEMPS-A, and TAS may help evaluate psychological factors.

Characteristics of children and adolescents with recurrent mental health emergency visits and clinicians' intervention tendencies.

Mental disorders affect approximately 15%-20% of childhood. However, due to various factors, these individuals do not benefit sufficiently from mental health services. Therefore, psychiatry emergency services become a key system in the need of psychiatric care for these children. This study aims to reveal the factors that predict recurrent admissions in children and adolescents admitted to the emergency department of a psychiatric hospital and the tendencies of clinicians during management. In our study, the data of patients aged 0-18 years who applied to the emergency department between 1 March 2022 and 01 March 2023 were scanned retrospectively. Participants who applied once were included in the 'single applicant' group, whereas patients who applied two or more times were included in the 'repeated applicants' group. A total of 1563 emergency applications were recorded by 785 different patients. A total of 62.2% of the patients visited the emergency department once, while 37.8% applied two or more times. Non-suicidal self-injury, delusion/hallucination, irritability and depression were significantly higher in recurrent applicants (P < 0.05). Psychotic disorder, bipolar disorder, major depression and borderline personality traits were significantly frequent in these patients (P < 0.05). Additionally, it was determined that the number of psychiatric diagnoses, referral time, need for chemical restraint, having a diagnosis of psychotic disorder or borderline personality traits increased the likelihood of recurrence. Our results indicate some special risk factors that increase the likelihood of recurrent emergency admissions in children and adolescents. Further research with larger sample sizes may elucidate the unique needs of these children in order to use of community resources beneficially.

Exploring the role of genetic factors in personality disorders among women with heroin dependence

Heroin dependence is a severe psychiatric issue that often coexists with mood disorders and personality disorders, which further compound the complexity and severity of the dependence. The utilization of genetic factors in predicting psychiatric disorders has made notable advancements. We enrolled female patients diagnosed with heroin dependence (n = 263) and assessed individuals with paranoid personality disorder, depressive personality disorder, antisocial personality disorder, and schizoid personality disorder based on the DSM-IV criteria. Our objective was to examine the single nucleotide polymorphisms (SNPs; rs174696, rs174699, rs4680, rs4818, rs737866, rs933271, rs12953076b, and rs44458044b) and their association with personality. We discovered a significant association of antisocial personality disorder with rs1544325, rs4680, and rs4818 (P &lt; 0.05). Additionally, hallucinogen use was associated with rs3792738 (P &lt; 0.05), rs10062367 (P &lt; 0.05), and rs1875999 (P &lt; 0.01). However, we did not observe a relationship between the SNPs and schizoid personality disorder, paranoid personality disorder, or depressive personality disorder. Heroin dependence is linked to specific personality disorders, particularly antisocial personality disorder. The influence of genetic factors could have a significant impact on the emergence of personality alterations linked to the consumption of heroin.

The Necessary Rapprochement of Negative Affectivity, Personality Disorder, and Depression.

The relationship between depression and personality has long been a topic of interest in the fields of psychiatry and psychology, but consensus remains elusive. This lack of consensus poses a significant challenge in both diagnosis and treatment, especially in situations when otherwise effective therapies for depression fail. Our article aims to address this issue by reviewing the historical and recent conceptualizations of the relationship between depression and personality pathology. Specifically, we focus on the trait domain of negative affectivity found in the International Classification of Diseases, 11th Edition (ICD-11) and the Alternative Model for Personality Disorders (AMPD) as a connecting link between the two phenomena. We review recent empirical studies evaluating the association of negative affectivity, personality, and depression, along with investigations of the relationship between depressive disorders and personality disorders. Additionally, we describe the Hierarchical Taxonomy of Psychopathology (HiTOP) and the AMPD as organizing frameworks for understanding depression within a broader personality framework. Based on the available evidence, we propose that depressive disorders must be assessed within the context of the patient's personality in order to maximize treatment outcomes. Ultimately, this integrated approach can guide clinicians in developing unified treatment protocols and facilitate early detection and intervention for factors contributing to depression in order to minimize treatment resistance.

Validation of the English-language version of the Morningness-Eveningness-Stability-Scale-improved (MESSi), and comparison with a measure of sleep inertia

ABSTRACT The Morningness-Eveningness-Stability-Scale-improved (MESSi) assesses three components of circadian functioning: Morning Affect (time to fully awaken), Eveningness (orientation/preference for evening activity), and Distinctness (amplitude of diurnal variations in functioning). Following the original German version, translations of the MESSi (including Spanish, Turkish, and Chinese) have been validated, but validity evidence for the English-language version has been lacking. The current study tested the factor structure, internal consistency, and predicted correlations of the English-language MESSi. A sample of 600 adults from an online recruitment platform (aged 18–78, mean = 41.31, SD = 13.149) completed an online survey including the MESSi, reduced Morningness-Eveningness Questionnaire (rMEQ), Sleep Inertia Questionnaire (SIQ), and measures of personality and depressive symptoms. Exploratory factor analysis exactly reproduced the three-component structure of Morning Affect (MA), Eveningness, and Distinctness, with all items loading strongly on their respective component. Confirmatory factor analysis of this structure showed acceptable fit. The three subscales showed good internal consistency and replicated previously reported correlations with depressive symptoms, sleep inertia, sleep quality, and personality. Further factor analysis combining the items of the MESSi, rMEQ, and SIQ replicated a previously found seven-factor structure: Cognitive, Emotional, and Physiological sleep inertia (SI), Responses to SI (including one MA item); Duration of SI (one SIQ item, 3/5 MA items); Morningness-Eveningness (MESSi Eveningness items, plus 3/5 rMEQ items); Distinctness (5/5 MESSi items). In conclusion, the English-language MESSi shows sound psychometric properties, but Morning Affect may be more suitably characterised as a measure of sleep inertia duration, rather than morningness preference.

Personality in Alcohol and Opioid Use Disorder: A Multiphasic Personality Questionnaire Study.

This study explored the relationship between personality attributes and substance use disorder (SUD). Research has identified specific personality dimensions, such as neuroticism, psychoticism, antisocial personality traits, paranoia, and anxiety, as contributing factors on the way to the initiation, continuation, and relapse of SUD. To explore this connection, we examined the personality profiles of subjects with alcohol use disorder (AUD) and opioid use disorder (OUD). A total of 928 subjects, 320 with AUD, 490 with OUD and 118 healthy controls (HC), in the age range of 16-65 years were recruited in the study. The Clinical Profile Sheet and the Multiphasic Personality Questionnaire (MPQ) were administered to HC and patients who fulfil the diagnostic criteria for substance dependence as defined by ICD-10 (WHO-1992). We found significant differences in personality profiles between individuals with OUD and AUD. Patients with AUD scored higher than OUD on the MPQ subscales for depression, mania, paranoia, and antisocial personality traits. All subscales of the MPQ showed elevated scores in subjects with SUD compared to HC. Elevated scores on the MPQ subscales suggest that personality factors may contribute to the pattern of substance use and misuse in this cohort.