This paper presents a performance analysis of a commercial pressurized water reactor (PWR) core loaded with accident-tolerant fuel (ATF) containing Mo/Cr metallic microcell UO2 pellets and a CrAl coating on the cladding. Metallic microcell UO2 pellets using additive materials, such as Mo and Cr, with coated cladding have been developed by the Korea Atomic Energy Research Institute (KAERI) for an OPR-1000 reactor. As demonstrated by the fuel pellet developed at KAERI, a metallic microcell UO2 pellet can increase the thermal conductivity of fuel pellets by forming a metallic film that encapsulates the UO2 to connect the metallic microcell and UO2 pellets; however, there has been no systematic core performance and safety analysis of the core with ATFs. In this study, core analysis with ATFs was conducted from a neutronic perspective. 1) The fuel assembly (FA) containing Mo/Cr metallic microcell UO2 pellets was analyzed using the lattice code STREAM developed by Ulsan National Institute of Science and Technology in terms of the Mo depletion chain and the impact of resonance treatment. 2) The initial and equilibrium cores were analyzed using STREAM/RAST-K 2.0 with respect to the impact of the additives and CrAl coating on the cycle length, power peaking, and fuel temperatures, etc. The reductions in the equilibrium core cycle length were 61, 44, and 65 effective full power days for each material type. 3) Finally, a rod ejection accident (REA) analysis was performed on the core using a Mo metallic microcell UO2 pellet and CrAl-coated ATF. Moreover, the maximum fuel centerline temperature of the ATF core was determined to be approximately 200 ℃ lower than that of the reference UO2 core. Furthermore, the presence of additional thermal margins in ATF cores for steady-state and accident transient scenarios was verified through a systematic neutronic analysis, and future studies will focus on the optimization of the ATF-loaded core by exploiting the extra margins achieved by ATFs and increasing the cycle length.