The dual-cooled annular fuel has two channels, with a shorter heat transfer path and a larger heat transfer area than solid fuel, which can effectively improve the safety of the reactor. It has excellent potential to improve the economy of the pressurized water reactor (PWR) and is considered to have a good development prospect. In this paper, the safety of the reactor with annular fuel assemblies under different transient conditions is analyzed using the system code NUSOL-SYS and the subchannel code NACAF, with the CPR1000 as the reference power plant. The analysis mainly includes the large break loss of coolant accident (LBLOCA), main steam line break accident (MSLB), loss of flow accident (LOFA), and rod ejection accident (REA) under nominal power and higher power density. The flow blockage accident and the combined accidents of LBLOCA and the flow blockage accident are also evaluated. The results show that during LBLOCA, the peak cladding temperature (PCT) of the core is only 833 K, much lower than that of the solid fuel. In addition, the departure from nucleate boiling ratio (DNBR) of annular fuel is larger during MSLB and LOFA, which means a more negligible risk of fuel damage. In REA, the average temperature of annular fuel is below 900 K, and the average enthalpy is below 200 kJ/kg, which is much lower than that of solid fuel. The results at 150 % power show that the performance of the core with annular fuel is still better than that of solid fuel at nominal power, except that the PCT during LBLOCA is slightly higher than solid fuel at nominal power. During the flow blockage accident, the results with different blockage areas show that a small proportion of blockage of the inner channel does not have a significant effect on the cladding temperature and that there is a risk of rupture when the inner channel is completely blocked. Finally, the results of the assumed combined accident show that the blockage of the inner channel before scram will significantly increase the PCT of the core and the time to complete the reflood during LBLOCA.