Department Of Clinical Research Articles

A Spotlight on Friedreich Ataxia: Optimising the Patient Journey from Diagnosis to Disease Management

This symposium was held on the first day of the European Academy of Neurology (EAN) Congress, with four main objectives: to raise awareness of Friedreich ataxia (FA) as a rare, progressive neurodegenerative disorder; to summarise the patient journey from identifying first symptoms in childhood and adolescence to reaching an accurate diagnosis; to discuss the burden of living with FA and highlight the benefit of improved communication and collaboration between members of the multidisciplinary team on reducing this burden on patients and their caregivers; and to summarise current management options within the field of FA and provide an overview of emerging therapies and active clinical trials. The symposium was chaired by Sylvia Boesch, a neurologist and senior staff member at the Medical University of Innsbruck, Austria, and Head of the Centre for Rare Movement Disorders, Innsbruck, Austria, who presented an overview of rare diseases in general and of FA. Mathieu Anheim, a neurologist at the Movement Disorders Unit, University Hospital of Strasbourg, France, followed with a description of the aetiology and symptomatology of FA. Lastly, Paola Giunti, a professorial research associate in the Department of Clinical and Movement Neurosciences, University College London Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, UK, explained the best approach to FA management, including a summary of clinical trials for emerging therapies in FA.

Treatment Reconciliation in Parkinson’s Disease Patients with Particular Reference to Wearing-off and Motor fluctuations: A Registry-based, Prospective, Observational Study

Introduction: Parkinson’s Disease (PD) is the second most frequent neurodegenerative disease and dopaminergic agents are frequently used as a treatment while ‘end of dose deterioration’ or ‘Wearing-Off (WO)’ phenomenon is common with these agents. Treatment reconciliation may be helpful in this situation and there is dearth of studies especially in India. Aim: To study the WO effects in patients of PD, their pharmacotherapy and outcome. Materials and Methods: This registry-based, prospective, observational, outcomes-based study was conducted in the Department of Clinical and Experimental Pharmacology, School of Tropical Medicine, Kolkata, West Bengal, India, in collaboration with Department of Neuromedicine of Kolkata Medical College and private clinics of a Neurologist from January 2020 to December 2021. An attempt was also undertaken to make a registry of Idiopathic Parkinson’s Disease (IPD) patients. WO Questionnaire 19-items (WOQ19), Movement Disorder Society-Unified Parkinson’s Disease Rating Scale (MDS-UPDRS Scale), The 39-items Parkinson’s Disease Questionnaire (PDQ-39 questionnaire), The 8-items Morisky Medication Adherence Scale (MMAS scale), suspected Adverse Drug Reaction (ADR) Reporting Form of Indian Pharmacoepia commission (version 1.3), World Health Organisation- Uppsala Monitoring Centre (WHO-UMC) Scale, Naranjo causality assessment scale, Hartwig and Seigel’s Severity Assessment Scale were used in the present study. The study was commenced after obtaining approval from institutional ethics committee. The data was then analysed with parametric or non parametric tests using (mean±Standard Deviation (SD), median, Fisher’s-exact test, Friedman’s Analysis of Variance (ANOVA) test, Wilcoxon matched pair signedrank test). Data collected and then statistically analysed by using WPS Excel version 2021 and GraphPad Prism version 9 software. Results: Total IPD patients were found to be 111 in the present study with a mean age of IPD patients as 61.85±7.20 years. Incidence of WO in the present study was found to be 40.5% among IPD patients. Most common characteristic of WO was found to be tremor in 104 (28.8%) patients followed by slowness of movement in 63 (17.5%) patients. WHO-UMC scale and Naranjo causality assesment scale both revealed 36.4% ADRs were probable category and 63.6% were possible category. MDS-UPDRS Score, PDQ-39 Score, MMAS-8 score significantly (p-value<0.05) improved during the course of treatment. Conclusion: Dose adjustment of syndopa was mostly used in the management of WO phenomenon and significant improvement in the quality of life of the patients was seen.

In memoriam Steven Greer MD 1928-2022.

Psycho-OncologyVolume 31, Issue 12 p. 2193-2194 OBITUARY In memoriam Steven Greer MD 1928–2022 Maggie Watson, Corresponding Author Maggie Watson [email protected] Research Department of Clinical, Educational and Health Psychology, University College London, UK Institute of Cancer Research, UK and Research and Innovation, University of Southern Queensland, Toowoomba, Queensland, Australia Correspondence Maggie Watson, Research Department of Clinical, Educational and Health Psychology, University College London, UK Institute of Cancer Research, UK and Research and Innovation, University of Southern Queensland, Toowoomba, QLD, Australia. Email: [email protected]Search for more papers by this authorClare Moynihan, Clare Moynihan Institute of Cancer Research, Sutton, UKSearch for more papers by this author Maggie Watson, Corresponding Author Maggie Watson [email protected] Research Department of Clinical, Educational and Health Psychology, University College London, UK Institute of Cancer Research, UK and Research and Innovation, University of Southern Queensland, Toowoomba, Queensland, Australia Correspondence Maggie Watson, Research Department of Clinical, Educational and Health Psychology, University College London, UK Institute of Cancer Research, UK and Research and Innovation, University of Southern Queensland, Toowoomba, QLD, Australia. Email: [email protected]Search for more papers by this authorClare Moynihan, Clare Moynihan Institute of Cancer Research, Sutton, UKSearch for more papers by this author First published: 25 October 2022 https://doi.org/10.1002/pon.6048Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume31, Issue12December 2022Pages 2193-2194 RelatedInformation

New trio for interventional cardiology submissions.

All correspondence relating to this article should be sent to cardiopulse@unicatt.it. From September 2022, a new team of three will be bringing their expertise in interventional cardiology to the process of sifting submissions and shepherding manuscripts for publication in the European Heart Journal (EHJ). Incoming deputy editor Emanuele Barbato, associate editors Tommaso Gori and Margaret McEntegart will take up a two-year tenure from outgoing deputy editor Javier Escaned MD, PhD, from Spain, and associate editors Julinda Mehilli MD, from Germany and Farouc Jaffer, MD, PhD, of the United States (Figure 1). Prof. Barbato graduated in medicine in 1997 and later obtained board certification in Cardiology at the University of Naples Federico II, in Italy. Whilst he was still a medical student, he completed a short-stay research fellowship at Duke University in North Carolina, US. He completed his PhD in Cardiovascular Pathophysiology at the University Tor Vergata in Rome, Italy in 2006. In the early years of the Millennium, he was a clinical research fellow at the Cardiovascular Research Center of Aalst, Belgium, where he eventually became Co-Director of the Cardiovascular Centre. In 2018, he became full Professor of Cardiology at the Department of Advanced Biomedical Sciences of the University of Naples Federico II. In 2022, he was appointed Full Professor of Cardiology at the Department of Clinical and Molecular Medicine of the Sapienza University of Rome.

A new way to explore ventricular-arterial coupling in young patients with untreated hypertension

Abstract Introduction Commonly assessed as arterial elastance (Ea) to ventricular end-systolic elastance (Ees) ratio, ventricular-arterial coupling (VAC) has independent prognostic value in hypertension. Aim To investigate whether new coupling indices may be able to identify left ventricular (LV) performance changes induced by blood pressure (BP) overload earlier than conventional ones. Materials and methods 50 young individuals were prospectively enrolled: 25 (40±8 years) newly diagnosed untreated hypertensives and 25 controls (38±9 yrs). All underwent at the same time carotid-femoral pulse wave velocity (PWV) measurement through a tonometer and an echocardiogram to calculate global longitudinal strain (GLS) and myocardial work efficiency (GWE). Two new indices of VAC were derived: PWV/GLS, previously validated and PWV/GWE, still unknown. Results ESV/SV ratio was lower in hypertensive (0.48±0.17) than in controls (0.57±0.14) but without any significant difference (p=0.18), whereas PWV/GLS was significantly lower in hypertensives than in controls (−0.45±0.19 vs −0.35±0.09 m/sec%; p=0.02). PWV/GLS ratio correlated with Ea/Ees (r=0.52; p<0.01), diastolic dysfunction degree (r=−0.59; p<0.001), age (r=−0.64; p<0.001), systolic BP (r=−0.41; p=0.002), diastolic BP (r=−0.39; p=0.005) and mean arterial pressure (MAP) (r=−0.40; p=0.004). PWV/GWE was higher in hypertensives than in controls (0.10±0.02 vs 0.08±0.01 m/sec%; p=0.001) and it was associated with Ea/Ees (r=−0.55; p=0.006), age (r=0.59; p<0.001), diastolic dysfunction degree (r=0.55; p<0.001), systolic BP (r=0.8; p<0.001), diastolic BP (r=0.5; p<0.001) and MAP (r=0.52; p<0.001). Conclusions Innovative indices of ventricular-arterial coupling could be more sensitive for investigating the impact of hypertension on LV performance. Funding Acknowledgement Type of funding sources: Public hospital(s). Main funding source(s): G. Martino University Hospital, Department of Clinical and Experimental Medicine - Cardiology Unit, University of Messina, Messina, Italy

Frequency of Performance of Advanced Practice Tasks Among Alumni from the Rutgers School of Health Professions Department of Clinical and Preventive Nutrition Sciences Graduate Programs

Frequency of Performance of Advanced Practice Tasks Among Alumni from the Rutgers School of Health Professions Department of Clinical and Preventive Nutrition Sciences Graduate Programs

Hereditary Angioedema Management: From Dealing to Leading

A two-part digital symposium series entitled ‘Hereditary Angioedema (HAE) Management: From Dealing to Leading,’ took place during the European Academy of Allergy and Clinical Immunology (EAACI) Hybrid Congress, held in Prague, Czechia, in July 2022. The first symposium, ‘The Journey Towards Disease Control in HAE’, held on 1st July 2022, was chaired by Markus Magerl, Department of Dermatology and Allergy, Charite Universitätsmedizin, Berlin, Germany. Speakers Grzegorz Porębski, Department of Clinical and Environmental Allergology, Jagiellonian University Medical College, Kraków, Poland, and Mauro Cancian, Department of Systems Medicine, University of Padova, Italy, discussed how the advent of new disease-specific HAE treatments have contributed to the evolution of the HAE management guidelines, and the resulting impact on the lives of patients with HAE. The latest international management guidelines from the World Allergy Organization (WAO)/EAACI newly define the goals of treatment in HAE as achieving total control of the disease and normalising patients’ lives, stressing that this can currently only be achieved by long-term prophylactic (LTP) treatment. The second symposium, ‘Making the Goals of HAE Management Achievable with Subcutaneous C1-Inhibitor’, held on 2­nd July 2022, was chaired by Pavlína Králíčková, Department of Clinical Immunology and Allergology, University Hospital Hradec Králové, Czechia, who also provided a brief overview of the development of the subcutaneous formulation of C1-inhibitor for LTP. Emel Aygören-Pürsün, Angioedema Clinic and Center for Hereditary Angioedema, University Hospital Frankfurt, Goethe University, Germany, and Teresa Caballero, Allergy Department, Hospital Universitario La Paz, Madrid, Spain, then used case studies to highlight the necessity of assessing and monitoring a patient’s disease activity, the associated quality of life, and disease control to allow for possible adaptations to the treatment plan. Both speakers also highlighted how the use of subcutaneous C1-inhibitor for LTP can contribute towards the achievement of the goals of HAE treatment, namely achieving total disease control and normalising patients’ lives.

Research Involvement Among Registered Dietitian Nutritionist Graduates of Rutgers’ School of Health Professions Department of Clinical and Preventive Nutrition Sciences

ObjectivesThe Rutgers School of Health Professions (SHP), Department of Clinical and Preventive Nutrition Sciences (DCPNS) offers three graduate programs with a strong focus on practice-based research competencies. This study assessed research involvement (RI) among registered dietitian nutritionist (RDN) graduates of Rutgers’ SHP DCPNS Entry-Level Master of Science in Clinical Nutrition, Master of Science in Clinical Nutrition, and Doctor of Clinical Nutrition programs, and evaluated if there was a relationship between RI scores and years of employment as an RDN. MethodsThis was a cross-sectional study using the validated practice-based dietitian research involvement survey (PBDRIS) tool and included questions about sociodemographic and professional characteristics. PBDRIS total possible score ranged from 16 to 80 and a higher total score indicated a higher RI of the participant. Data were collected via an online survey and the sample included 94 alumni from the past 25 years (usable response rate of 32.5%). Descriptive statistics and Spearman correlation tests were conducted. ResultsOf the 94 study participants, 90.9% (n = 80) were female, 89.8% (n = 79), white or Caucasian, and the median age was 44.5 years. The majority of participants reported working in clinical practice (n = 69, 73.4%) and their median years of employment as an RDN was 22.0 years. The median PBDRIS total score was 54.0 (out of 80.0). Level 1, consisting of applying evidence-based practice (EBP), was the highest median sub-score (19.0 out of 20.0). The lowest median sub-score was level 4 (11.0 out of 20.0), involving activities about leadership in research. The most and least frequently reported activities were “applying EBP” (n = 78, 83.0%), and “applying for grant funding” (n = 59, 62.8%), respectively. There was a statistically significant medium, positive correlation between years of employment as an RDN and PBDRIS total scores (r = 0.396, n = 85, p < 0.001). ConclusionsRDN alumni from the Rutgers SHP DCPNS had RI scores which likely reflect the unique research-based focus of the program curricula. With more years of experience as an RDN, RI scores increased. Funding SourcesRutgers School of Health Professions, Department of Clinical and Preventive Nutrition Sciences.

A personal obituary for Prof. Dr. med. Giancarlo Biamino

A personal obituary for Prof. Dr. med. Giancarlo Biamino

Low IgG trough and lymphocyte subset counts are associated with hospitalization for COVID-19 in patients with primary antibody deficiency

Low IgG trough and lymphocyte subset counts are associated with hospitalization for COVID-19 in patients with primary antibody deficiency

791 Virtual visits in HF outpatient management during COVID-19-related lockdown

AimsFollowing the COVID‐19 pandemic‐related lockdown period in Italy, people have experienced psycho-physical distress. Many hospitals were converted in COVID-19 healthcare places and many specialist outpatient’s services were drastically reduced. Virtual visits may represent a strategy to overcome the lack of HF outpatient’s services, during this period. Our own experience underlines the importance of virtual visits to face the clinical and health status deterioration, associated with COVID-19, in HF outpatients.Methods and resultsWe conducted an observational study, enrolling consecutive HF outpatients, previously hospitalized at the Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences of Sapienza University of Rome, who were discharged within 31 March 2019, and 30 April 2019. Two follow-up periods were scheduled: (i) within 20–30 days after the beginning of lockdown (ii) at 3 months after lockdown’s end. Virtual visits were conducted through telephone, assessing changes in clinical and health status; the latter was assessed through the short version of the Kansas City Cardiomyopathy Questionnaire (KCCQ-12). According to the presence of at least one sign of HF deterioration, patients were divided into two groups: Group 1: patients who experienced a modification in at least one clinical parameter suggestive of HF deterioration. Group 2: patients who do not experienced any modification of HF deterioration clinical parameter. KCCQ-12 mean scores were compared between the two groups, at both scheduled virtual visits, in order to evaluate any change in HF outpatients’ health status, during and after the COVID-19-related-lockdown. 160 HF outpatients have been included in the study: 63 in the group 1, 97 in the group 2. At the first virtual visit, group 1 reported significantly lower mean KCCQ-12 score, compared to group 2 [46.2 (±14.6) vs. 53.8 (±11); CI: 95% 11.6 to − 3.6; P = 0.0003]. At the second virtual visit, group 1 patients reported a slightly, but not statistically significant, lower mean KCCQ-12 score, compared to group 2 [52.2 (± 13.3) vs. 53.1(±14.4); 95% CI: −5.4 to 3.6; P = 0.69]. Comparing the KCCQ-12 mean scores of each group between the two scheduled virtual visits, group 1 reported a statistically significant increase at the second visit, compared to the first [52.2 (±13.3) vs. 46.2 (±14.6); CI: 95% 1.1–11; P = 0.017]. Group 2 showed no statistically significant variation of mean KCCQ-12 score between the two follow-up periods [53.1 (±14.4) vs. 53.8 (±11); CI: 95% −4.3 to 3; P = 0.704].Conclusionswe observed a significant worsening of health status in HF outpatients who have experienced clinical deterioration. Therefore, patients were either hospitalized or received the optimization of diuretic and anti-hypertensive therapies. A significant health status improvement was observed at three months after the end of the lockdown, suggesting the importance of virtual visit as an adequate method to follow-up HF outpatients, reporting particular benefits in those with worsening of HF clinical signs and health status.

APA/APAGS Award for Distinguished Graduate Student in Professional Psychology: Gabriel Cartagena.

The APA/APAGS Award for Distinguished Graduate Student in Professional Psychology is awarded annually by the APA Board of Professional Affairs (BPA) and the American Psychological Association of Graduate Students (APAGS) to a graduate student who has demonstrated outstanding practice and application of psychology. A 2021 award winner is Gabriel Cartagena, MS. Cartagena is a graduate student in the Department of Clinical and Health Psychology at the University of Florida and intern at the Yale University Doctoral Internship in Clinical and Community Psychology's Behavioral Medicine program. At the University of Florida, he serves as the director and co-creator of the student-run Equal Access Behavioral Health Clinic and Integrated Primary Care Clinic, providing free psychological services to underserved/underinsured community members. He is dedicated to teaching others about disparities by participating in panels, creating educational content for his department and university, and most importantly, volunteering his time to directly provide care and service to minimize disparities. His leadership has resulted in lasting change at UF on many levels and he plans to continue to address health disparities in the future with the many tools of a citizen psychologist. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Thyroidectomy for Cancer: The Surgeon and the Parathyroid Glands Sparing.

Background: The diagnosis of thyroid cancer is continuously increasing and consequently the amount of thyroidectomy. Notwithstanding the actual surgical skill, postoperative hypoparathyroidism still represents its most frequent complication. The aims of the present study are to analyze the rate of postoperative hypoparathyroidism after thyroidectomy, performed for cancer by a single first operator, without any technological aid, and to compare the data to those obtained adopting the most recent technological adjuncts developed to reduce the postoperative hypoparathyroidism. Methods: During the period 1997–2020 at the Endocrine Surgery Unit of the Department of Clinical and Experimental Medicine of the University of Florence, 1648 consecutive extracapsular thyroidectomies for cancer (401 with central compartment node dissection) were performed. The percentage of hypoparathyroidism, temporary or permanent, was recorded both in the first period (Group A) and in the second, most recent period (Group B). Total thyroidectomies were compared either with those with central compartment dissection and lobectomies. Minimally invasive procedures (MIT, MIVAT, some transoral) were also compared with conventional. Fisher’s exact and Chi-square tests were used for comparison of categorical variables. p < 0.01 was considered statistically significant. Furthermore, a literature research from PubMed® has been performed, considering the most available tools to better identify parathyroid glands during thyroidectomy, in order to reduce the postoperative hypoparathyroidism. We grouped and analyzed them by technological affinity. Results: On the 1648 thyroidectomies enrolled for the study, the histotype was differentiated in 93.93 % of cases, medullary in 4% and poorly differentiated in the remaining 2.06%. Total extracapsular thyroidectomy and lobectomy were performed respectively in 95.45% and 4.55%. We recorded a total of 318 (19.29%) cases of hypocalcemia, with permanent hypoparathyroidism in 11 (0.66%). In regard to the literature, four categories of tools to facilitate the identification of the parathyroids were identified: (a) vital dye; (b) optical devices; (c) autofluorescence of parathyroids; and (d) autofluorescence enhanced by contrast media. Postoperative hypoparathyroidism had a variable range in the different groups. Conclusions: Our data confirm that the incidence of post-surgical hypoparathyroidism is extremely low in the high volume centers. Its potential reduction adopting technological adjuncts is difficult to estimate, and their cost, together with complexity of application, do not allow immediate routine use. The trend towards increasingly unilateral surgery in thyroid carcinoma, as confirmed by our results in case of lobectomy, is expected to really contribute to a further reduction of postsurgical hypoparathyroidism.

Developing a clinical psychology service for patients affected by Covid-19: Reflections from Leeds Department of Clinical and Health Psychology

The paper discusses a new clinical psychology service developed during the first Covid-19 pandemic to offer psychological assessment and intervention to patients diagnosed with Covid-19. Information about the type of referrals and interventions offered were collected. Reflections of the service were captured from a patient and therapist perspective.

Impact of the COVID-19 Pandemic on Family Wellbeing in the Context of Neurodevelopmental Disorders.

ObjectiveThe primary aim was to assess both the type and degree of impact of the COVID-19 pandemic on child and family wellbeing in a cohort with neurodevelopmental disorders.DesignThis was a single time-point observational study utilizing a combination of surveys and standardized measures, which were administered to parents by researchers by telephone.SettingThe Child and Adolescent Neuropsychiatric Clinic of the Department of Clinical and Experimental Medicine, Catania University, Italy.ParticipantsIn total, 200 caregivers completed the questionnaires on behalf of themselves and their child. They were predominantly mothers (88.00%) and primary caregivers (93.50%), with a mean age of 42.84 years (sd = 7.13).Primary and Secondary Outcomes MeasuresA questionnaire featured in a previous study was used to assess the impact of COVID-19 on general wellbeing, types of support, family health, home-based learning, and child behaviors. Children’s diagnoses were recorded. Caregivers provided information about physical, mental, financial, and vocational wellbeing, and completed several standardised measures of mental health and well-being: the Kessler Psychological Distress Scale - K6; the General Anxiety Disorder Scale – GAD-2; and the WHO Well-being Scale – WHO-5.ResultsOverall, 58.50% of respondents agreed somewhat or strongly that their child’s overall health and wellbeing had been impacted by the pandemic, while 47.74% felt that their own wellbeing as parents had been affected. Whilst home-based learning and disruption to services for children were noted as being significant, child wellbeing appeared to not be correlated with these but rather to restrictions, home isolation, and disruption to routine.ConclusionChildren with neurocognitive disorders and their families have been substantially impacted by the COVID-19 pandemic. It is expected that targeted resources and support services will be required in response to this increase in need.

Answering epidemiologic rheumatologic questions by cooperation with the large population-based SHIP cohort-findings with relevance for the diagnosis of axial spondyloarthritis (axSpA)

In diesem Artikel wird dargestellt, wie sich Fragestellungen hinsichtlich der rheumatischen Erkrankung axiale Spondyloarthritis (axSpA) in Zusammenhang mit der Verfügbarkeit neuer bildgebender Verfahren und neuer Medikamente über mehr als zwei Jahrzehnte in einer rheumatologischen Forschungsgruppe entwickelt haben. Insbesondere in den letzten Jahren ergaben sich durch die Kooperation mit der SHIP („Study of Health in Pomerania“)-Kohorte neue grundlegende Aspekte. Dabei bestand eine intensive Kooperation zwischen der Ruhr-Universität Bochum (Rheumazentrum Ruhrgebiet) und der Universitätsmedizin Greifswald (Forschungsverbund „Community Medicine“). Das Design der SHIP-Kohorte ist schon vor 10 Jahren veröffentlicht worden und der Kohortenansatz wurde im Bundesgesundheitsblatt dargestellt, wobei zentrale methodische Fragen ausführlich erörtert wurden. Im Jahr 2014 wurde ein Kooperationsprojekt des Rheumazentrums Ruhrgebiet/Ruhr-Universität Bochum mit der Abteilung Klinisch-Epidemiologische Forschung (KEF) von SHIP vereinbart, aus dem bereits interessante Ergebnisse hochrangig publiziert wurden. Um das Potenzial solcher Kooperationen zu betonen, werden wesentliche Inhalte mit Fokus auf die Magnetresonanztomographie (MRT) im Folgenden, auch unter historischen Aspekten, dargestellt.

"Concerns About Employment After Graduation: A Survey of First Professional Year Pharmacy Students"

Jennifer Obi1, Ewanna Brown1, Essence Bell1 and Bisrat Hailemeskel*2 Author Affiliations 1Doctor of Pharmacy student, Howard University, NW Washington, USA 2Professor & Vice chair, Department of Clinical & Administrative Pharmacy Sciences, College of Pharmacy, Howard University, NW Washington, USA Received: April 22, 2021 | Published: May 24, 2021 Corresponding author: Bisrat Hailemeskel, Professor & Vice chair, Department of Clinical & Administrative Pharmacy Sciences, College of Pharmacy,Howard University, NW Washington, DC, USA DOI: 10.26717/BJSTR.2021.36.005790

Impact of Virtual Learning in a Pharmacy Program

Michelle Brooks1, Oliver Nimoh1, Nathaniel Oppong1 and Bisrat Hailemeskel*2 Author Affiliations 1Doctor of Pharmacy Student, USA 2Professor of Clinical Pharmacy & Vice Chair, Department of Clinical & Administrative Pharmacy Sciences, College of Pharmacy, Howard University, NW Washington, USA Received: April 22, 2021 | Published: May 24, 2021 Corresponding author: Bisrat Hailemeskel, Professor of Clinical Pharmacy & Vice Chair, Clinical & Administrative Pharmacy Sciences, College of Pharmacy, Howard University, 2300 4th Street, NW, Washington, DC 20059, USA DOI: 10.26717/BJSTR.2021.36.005792

First person – Tobias Beigl, Ine Kjosås and Emilie Seljeseth

ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Tobias Beigl, Ine Kjosås and Emilie Seljeseth are co-first authors on ‘Efficient and crucial quality control of HAP1 cell ploidy status’, published in BiO. Tobias is a PhD student in the laboratory of Professor Walter E. Aulitzky at the Dr Margarete Fischer-Bosch Institute for Clinical Pharmacology, Stuttgart, investigating protein biology from the N- to the C-terminus and back again. Ine is a Master's student in the laboratory of Professor Thomas Arnesen at the University of Bergen, Institute of Biological Science. Emilie is a Master's student in the laboratory of Nadra J. Nilsen at NTNU Department of Clinical and Molecular Medicine in Trondheim, investigating the dual role of immune cells in cancer.

Virus-Negative Myopericarditis in Human Coronavirus Infection: Report From an Autopsy Series.

Virus-Negative Myopericarditis in Human Coronavirus Infection: Report From an Autopsy Series.