A new species of Candida has been recovered 40 times from necrotic cactus tissue occurring in widely separated geographic areas. The organism has been named Candida mucilagina because of the extremely slimy, almost watery appearance of its colonies on solid media. Eleven strains were isolated in Baja California Sur, Mexico, where its principal host plant was Stenocereus gummosis (agria), and 29 strains came from rotting cladodes of Opuntia inermis in New South Wales and Queensland, Australia. The base composition of the nuclear deoxyribonucleic acid of C. mucilagina is 43.2 to 44.0 mol% (range of five strains). The type strain of C. mucilagina is UCD-FS&T 76-236C (= ATCC 42174 = CBS 7071).