An interim analysis is presented of the caries prophylactic effects of ingested water fluoride in children aged 5 to 12 years in Newburgh, as compared with children of the same ages in fluoride-free Kingston. These data show that among the 6- to 9-year-old children in Newburgh there are 55 per cent less DMF teeth per 100 erupted permanent teeth, as compared with the same-aged children in Kingston. Among the 10- to 12-year-old children there is a difference of 43 per cent. In the deciduous dentition, the reduction in def teeth among Newburgh children ranged from 59 per cent in the 5-year-old, to 12 per cent in the 8-year-old children, as compared with those in Kingston. The total dental caries experience for both the permanent and deciduous dentitions show that for each age level from 6 to 12 years the Newburgh children experienced dental decay in approximately two teeth less than the Kingston children. Among the 5- to 7-year-old children there were approximately twice as many with all of their deciduous canines and deciduous molars present and caries-free as were noted in Kingston. The details are presented of the dentofacial growth and development study among 1,000 children aged 6 to 10 years in Newburgh and Kingston.