Objective: This study explored the factors influencing the development of empathy in a dentist-patient relationship.
 Design: An exploratory qualitative study.
 Place and duration of the study: Khyber Medical University KPK, Pakistan October 2019 to April 2020.was conducted during 2019-2020
 Methodology: This exploratory qualitative study was conducted during 2019-2020. It was conducted on 12 dental surgeons, recruited from four major dental clinical specialties. A purposive sampling technique was used. In-depth interviews were conducted through a semi-structured format. The interviews were audio recorded, transcribed verbatim and analyzed, using the thematic analysis framework.
 Results: Three themes were extracted from data. 1) Institutionalization of empathy, indicating a need for incorporating empathy in undergraduate and postgraduate dental curriculum, 2) Barriers in the path of empathetic attitude, including a variety of factors hampering the development of empathy in a dentist-patient relationship and 3) Cultivating a Culture of empathy for better health care provision, indicating a need for changing the collective attitude of all health care professionals, administrative staff, and students. The participants of the study observed that development of empathy in a dentist-patient relationship includes a wide range of factors, ranging from curricular, personal, social, organizational, and cultural. These factors elaborate that empathy is a multidimensional phenomenon with roots deeply entrenched in professional and personal domains.