The materials utilized in various domains of prosthodontics have changed overtime. In recent years, patients have been requesting a metal-free, lightweight, and tooth-colored prosthesis. In dentistry, metal and other ceramics are used in a variety of treatment methods. Polyetheretherketone (PEEK) can be employed in a variety of ways in prosthodontics. PEEK is being investigated as an alternative to metal and glass ceramics due to their acceptable fracture resistance, shock-absorbing capabilities, and improved stress distribution. Due to its favorable mechanical and chemical properties, PEEK is recognized as a high-performance polymer in engineering and medical applications. In dentistry, a material must have excellent biocompatibility, strong mechanical qualities, be resistant to high temperatures, have a low moisture absorption and elasticity modulus, be flexible, and have a high chemical wear resistance. PEEK material possesses all of these characteristics, making it ideal for use in dentistry. Using PEEK with computer-aided design and computer-aided manufacturing fabrication (CAD/CAM) will allow us to save natural teeth in tough situations. The technique allows the patient to have upgrades that are physiologically and technically superior in processing and improve their appearance. Dental rehabilitation with complete satisfaction is in doubt, mostly because of the imperfect adaptation of the crown. Hence, the restoration of teeth using PEEK with CAD/CAM technology as an alternative to glass or metal ceramics provides an excellent opportunity for better esthetic restoration and patient satisfaction. In this present case presentation, we highlighted two clinical cases showing teeth in the upper left arch and two teeth in the lower right region of the jaw using CAD/CAM-fabricated PEEK post, core, and PEEK crown, which were briefly demonstrated.