Background:Immediate placement of implants in post-extraction sockets is a common and well-established treatment modality. However, extraction sockets with periapical pathology may negatively impact the outcome of this treatment procedure. Objective: The aim of this study was to evaluate the clinical outcomes of immediate placement of dental implants in infected extraction sockets with periapical pathology. Materials and Methods: The study included 37 patients who underwent tooth extraction with periapical pathology and immediate 151 Bio3 GmbH (Germany) implants placement. Postoperative results; implant survival, implant failure, marginal bone loss (MBL), and patient-reported function of the implants were assessed clinically and radiographically. Results: There were no complications during implant placement and in the postoperative period, no signs of infection around the implants were detected at the follow-up visit 4 weeks after implant placement, the soft tissues were in good condition, as evidenced by their healthy color and texture. The mean RFA for151 implants was 63.7 ISQ (implant stability), and after 3-5 months, respectively, 72.4 ISQ. The mean MBL after 12 months was 0.94, after 36 months the mean MBL was 1.28, at 60 months follow-up the mean MBL was 1.42. The functional and aesthetic results of prosthetic restoration were satisfied by the patients, as chewing function was restored, the esthetics of the facial profile and occlusion improved. The success rate of immediate implants after 5 years was 96.8%, and shows a similar survival rate to the published success rates for immediate implants placed in non-infected sites. Conclusion: Evidence suggests that immediate placement of implants in areas with periapical infections is a predictable and effective treatment protocol if the areas are thoroughly debrided prior to implant placement, high implants stability is achieved during implant placement, and systemic antibiotics are used.
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