Dental College Research Articles

Does body surface area of children affect the oral health?

To evaluate relationship between oral health and body surface area among children. The observational, cross-sectional study was conducted from January to February /2022 after approval from the ethics review committee of the College of Dentistry, University of Baghdad, Baghdad, Iraq, and comprised children of either gender aged 6-8 years who were randomly selected from primary schools in the city. Body surface area was calculated geometrically using different formulas, and the DuBois formula was used to make the intervals. The estimated body surface area values were broadly divided into four intervals: 0.8-0.9, >0.9-1.0, >1.0-1.1, >1.1. Dental caries was examined using the World Health Organisation criteria related to decayed, missed and filled teeth and surfaces for primary and permanent teeth. Dental plaque and gingival health status were measured using plaque and gingival indices. Data was analysed using SPSS 22. There were 240 subjects. There was no significant difference in terms of mean body surface area intervals of decayed, missed and filled teeth and surfaces for primary and permanent teeth (p>0.05). The mean values of gingival index showed significant differences across body surface area intervals (p<0.05). Mean plaque index values showed no significant differences (p>0.05). No relationship between body surface area and caries experience of primary and permanent teeth was found. However, increasing the body surface area increased gingival inflammation.

Comparative Analysis of Impacted Mandibular Third Molar Root Proximity to the Mandibular Canal using Orthopantomography and Cone-beam Computed Tomography Imaging Modalities: A Pilot Study

Abstract Introduction: Fully detect risks of nerve damage, which can lead to temporary or permanent issues. Cone-beam computed tomography (CBCT) offers a three-dimensional (3D) view, providing more detailed visualisation of anatomical structures and their spatial relationships, which improves the accuracy of predicting nerve exposure. The study aims to evaluate and compare these imaging techniques’ effectiveness in categorising the relationship between third molars and the inferior alveolar canal, emphasising the importance of precise imaging for safer surgical outcomes. Materials and Methods: A pilot study involving 20 patients, representing 10% of the total sample size of 200, was conducted at Ahmedabad Dental College’s Department of Oral Medicine and Radiology. Investigators, trained to interpret radiological images from orthopantomography (OPG) and CBCT, compared their interpretations with those of two experts. A high inter-rater reliability was confirmed with a kappa statistic of 0.98. Following ethical approval, data were retrospectively collected from 20 cases, with digital OPG and CBCT images analysed and classified according to established criteria. Results: The results revealed a significant association between the results diagnosed through OPG and CBCT indicating similarity in their diagnosis. It was also seen that there was no bias towards the gender and the distribution was similar in case of diagnosis through OPG or CBCT. Conclusion: CBCT demands an in-depth understanding of anatomy and pathology, coupled with proficiency in operating imaging software and the ability to identify abnormalities in cross-sectional images. When executed and interpreted accurately, CBCT proves to be an exceptionally valuable tool in clinical dental practice. Its detailed 3D imaging capabilities enhance the assessment of complex cases, such as those involving intricate anatomical structures and pathologies. By providing comprehensive views that surpass traditional two-dimensional imaging, CBCT aids in precise diagnosis and treatment planning, making it an indispensable resource for addressing various dental conditions effectively.

Cocaine-induced destruction of the palate: a diagnostic and management challenge

Cocaine usage is increasing at a rate faster than population growth worldwide. The habitual and chronic insufflation of pulverised cocaine is associated with the progressive destruction of the osseocartilaginous structures of the midface, termed cocaine-induced midline destructive lesions (CIMDLs). These entities present a challenging diagnostic picture, mimicking other infectious, malignant and inflammatory conditions associated with midface destruction. CIMDLs can present along a wide spectrum of disease, with minimal palatal perforation to extensive sinonasal destruction. With the increasing usage of cocaine, there is likely to be a concurrent increase in patients presenting to emergency departments with these destructive entities. Therefore, there is a need to create awareness of this uncommon entity and to document a systematic approach that must be adopted to reach a definitive diagnosis which will subsequently inform management. We report four clinical cases of CIMDLs at varying stages of the disease process which presented to the Dublin Dental University Hospital between January 2023 and June 2024 and document their multidisciplinary management from initial presentation to eventual treatment.

Does enamel deproteinisation with 10% papain affect shear bond strength of orthodontic adhesives: a randomised controlled trial.

To evaluate the effect of 10% papain as an enamel deproteinising agent on the shear bond strength (SBS) of three orthodontic adhesives: Transbond XT, resin-modified glass ionomer cement (RMGIC) and Biofix. Single-centre, double-blinded, split-mouth randomised controlled trial. Department of Orthodontics and Dentofacial Orthopaedics, Nair Hospital Dental College, Mumbai, India. A total of 20 participants requiring bilateral premolar extraction for fixed orthodontic treatment in both the maxillary and mandibular arches were included in this study. In total, 80 premolars from the above-mentioned participants were divided into four groups as follows: group A: Transbond XT deproteinised with 10% papain gel; group B: Biofix deproteinised with 10% papain gel; group C: RMGIC deproteinised with 10% papain gel; and group D: Transbond XT without enamel deproteinisation as a control group-bonded as instructed by the manufacturer. After deproteinisation, brackets were bonded and after a follow-up period of 28 days, the teeth were extracted. The SBS was then measured using the Universal Testing Machine. The force needed to shear the bracket was documented, and bond strengths were subsequently calculated in megapascals (MPa). The obtained results were subjected to statistical analysis and one-way ANOVA was performed to compare the mean SBS between the groups. Subsequently, pairwise comparisons were conducted using Tukey's post hoc test. There was a statistically significant difference in SBS among all groups (P = 0.002). The SBS of TransXT with deproteinisation increased significantly compared with TransXT without deproteinisation (P = 0.03). There was no statistically significant difference between the SBS of TransXT without deproteinisation and RMGIC (P = 0.47) and Biofix (P = 0.39), both with deproteinisation. The use of 10% papain for deproteinising enamel improved the SBS of all materials. Deproteinising improved the SBS of RMGIC and Biofix to the level of TransXT without deproteinisation.

Targeting USP14/UCHL5: A Breakthrough Approach to Overcoming Treatment-Resistant FLT3-ITD-Positive AML.

FMS-like tyrosine kinase 3 (FLT3) internal tandem duplication (ITD) mutations in acute myeloid leukemia (AML) are associated with poor prognosis and therapy resistance. This study aimed to demonstrate that inhibiting the deubiquitinating enzymes ubiquitin-specific peptidase 14 (USP14) and ubiquitin C-terminal hydrolase L5 (UCHL5) (USP14/UCHL5) with b-AP15 or the organogold compound auranofin (AUR) induces apoptosis in the ITD-transformed human leukemia cell line MV4-11 and mononuclear leukocytes derived from patients with FLT3-ITD-positive AML. This study included patients diagnosed with AML at Tokyo Medical and Dental University Hospital between January 2018 and July 2024. Both treatments blocked downstream FLT3 pathway events, with the effects potentiated by USP14 knockdown. Both treatments inhibited FLT3 deubiquitination via K48 and disrupted translation initiation via 4EBP1, a downstream FLT3 target. FLT3 was downregulated in the leukemic cells, with the associated activation of stress-related MAP kinase pathways and increased NF-E2-related factor 2. Furthermore, the overexpression of B-cell lymphoma-extra-large and myeloid cell leukemia-1 prevented the cell death caused by b-AP15 and AUR. These results suggest that inhibiting USP14/UCHL5, which involves multiple regulatory mechanisms, is a promising target for novel therapies for treatment-resistant FLT3-ITD-positive AML.

Assessment of Iraqi dental practitioners' and undergraduate students' knowledge regarding dentin hypersensitivity management: A cross-sectional study

Objective: The characteristic of dentin hypersensitivity is brief, intense pain that results from exposed dentin in reaction to a variety of stimuli, including mechanical, thermal, osmotic, or chemical factors. This study aimed to evaluate the level of knowledge among undergraduate students and practicing dentists in Karbala City, Iraq, concerning the mechanisms, etiology, and treatment of dentin hypersensitivity (DH). Methods: 102 surveys were distributed via Google Forms to general practitioners and fourth- and fifth-year dental students at the Kerbala College of Dentistry in Iraq. The data were inputted into Microsoft Excel and analyzed using SPSS 22.0 for Windows as frequency distribution tables and figures. Results: Despite the differences in comprehension and expertise between students and dentists, a comparative analysis of their responses to various questions revealed several similarities. According to the survey, 28.8% of students reported that 10% of patients suffered from DH, while 32% of dentists reported the same. Additionally, 72% of dentists and 71.2% of students stated that DH is a severe problem for patients. Both dentists, 30%, and 26.9% of students, indicated that DH lasted for less than 2 weeks. According to dentists and students, females are more affected by DH (74%; n=37) and (71%; n=37), respectively. Conclusion: Students and dentists showed a similar level of knowledge on DH.

Current Status of Cooperation System Between Pediatric Dentistry and Orthodontics in Kyushu Dental University Hospital

Current Status of Cooperation System Between Pediatric Dentistry and Orthodontics in Kyushu Dental University Hospital

Current Status and Future Prospects of the Jaw Deformity in the Kyushu Dental University Hospital

Current Status and Future Prospects of the Jaw Deformity in the Kyushu Dental University Hospital

The current treatment and Future Prospects of the Cleft Lip and/or Palate Center, Kyushu Dental University Hospitat

The current treatment and Future Prospects of the Cleft Lip and/or Palate Center, Kyushu Dental University Hospitat

Pertinence of Five Different Regression Equations of Mixed Dentition Analysis in West Godavari District Children: A Comparative Study.

The orthodontic diagnosis and treatment planning are the fundamental goals during the mixed dentition period. Numerous methods have been proposed to date. The study was designed to determine the mesiodistal (MD) widths of the lower permanent canines and premolars from Tanaka and Johnston, regression equation (RE) proposed for north Indian population (RE-NIP), Bernabé and Flores-Mir C, Moyers', and Ling and Wong mixed dentition analysis (MDA) and to determine the correlation coefficients for the Eluru population. The study population was selected using cluster random sampling. A total of 3,572 children were clinically examined from the Outpatient Department of Pediatric and Preventive Dentistry, St Joseph Dental College and Hospital, Eluru district, Andhra Pradesh. Out of these, 140 children aged 11-16 years were randomly selected for the study based on the inclusion and exclusion criteria. The MD width of permanent incisors, canines, premolars, and molars was measured with the help of a digital vernier caliper; summed up and compared with the above-mentioned REs. The data obtained were subjected to statistical analysis using SPSS version 22, employing Student's t-test, Pearson correlation coefficient, and Kruskal-Wallis test. The RE-NIP underestimated the values, whereas the remaining equations overestimated the sum of permanent canines and premolars in both arches in the study population. The predicted values obtained from the abovementioned methods overestimated the actual values, and a new RE for the Eluru population should be suggested to better represent the size of unerupted canines and premolars. Measuring the MD widths of the upper and lower permanent incisors and molars during the mixed dentition period from different REs will help a pedodontist in proper treatment planning to predict the MD width of unerupted canines and premolars. Kanaparthi S, Done V, P Madu GS, et al. Pertinence of Five Different Regression Equations of Mixed Dentition Analysis in West Godavari District Children: A Comparative Study. Int J Clin Pediatr Dent 2024;17(8):871-876.

Blood flow assessment of gastric tube with indocyanine green fluorescence angiography and postoperative endoscopy during esophagectomy: indocyanine green enhancement time indicated congestion

BackgroundDuring esophagectomy, evaluation of blood supply to the gastric tube is critically important to estimate and avoid anastomotic complications. This retrospective study investigated the relationship between indocyanine green (ICG) fluorescence angiography during esophagectomy and postoperative endoscopy findings, especially mucosal color change.MethodsThis study retrospectively collected data from 86 patients who underwent subtotal esophagectomy and reconstruction using a gastric tube for esophageal cancer at the Tokyo Medical and Dental University between 2017 and 2020. The flow speed of ICG fluorescence in the gastric tube was evaluated during the operation. Additionally, the main root of ICG enhancement and pattern of ICG distribution in the gastric tube were evaluated. On postoperative day 1 (POD1), the change in the mucosal color to white, thought to reflect ischemia, or black, thought to reflect congestion of the proximal gastric tube, was evaluated. The correlations between these factors, clinical parameters, and surgical outcomes were evaluated. Univariate and multivariate analyses used logistic regression to identify the risk factors affecting mucosal color change.ResultsMultivariate analyses revealed that the only independent significant predictor of mucosal congestion on POD1 was the ICG enhancement time of the right gastric tube tip (odds ratio, 14.49; 95% confidential interval, 2.41–87.24; P = 0.004).ConclusionsThis study indicated that the ICG enhancement time is related to venous malperfusion and congestion rather than arterial malperfusion and ischemia.

Light gradient boost tree classifier predictions on appendicitis with periodontal disease from biochemical and clinical parameters.

Untreated periodontitis significantly increases the risk of tooth loss, often delaying treatment due to asymptomatic phases. Recent studies have increasingly associated poor dental health with conditions such as rheumatoid arthritis, diabetes, obesity, pneumonia, cardiovascular disease, and renal illness. Despite these connections, limited research has investigated the relationship between appendicitis and periodontal disease. This study aims to predict appendicitis in patients with periodontal disease using biochemical and clinical parameters through the application of a light gradient boost tree classifier. Data from 125 patient records at Saveetha Institute of Dental College and Medical College were pre-processed and analyzed. We utilized data preprocessing techniques, feature selection methods, and model development approaches to estimate the risk of appendicitis in patients with periodontitis. Both Random Forest and Light Gradient Boosting algorithms were evaluated for accuracy using confusion matrices to assess their predictive performance. The Random Forest model achieved an accuracy of 94%, demonstrating robust predictive capability in this context. In contrast, the Light Gradient Boost algorithms achieved a significantly higher accuracy of 98%, underscoring their superior predictive efficiency. This substantial difference highlights the importance of algorithm selection and optimization in developing reliable predictive models. The higher accuracy of Light Gradient Boost algorithms suggests effective minimization of prediction errors and improved differentiation between appendicitis with periodontitis and healthy states. Our study identifies age, white blood cell count, and symptom duration as pivotal predictors for detecting concurrent periodontitis in acute appendicitis cases. The newly developed prediction model introduces a novel and promising approach, providing valuable insights into distinguishing between periodontitis and acute appendicitis. These findings highlight the potential to improve diagnostic accuracy and support informed clinical decision-making in patients presenting with both conditions, offering new avenues for optimizing patient care strategies.

Awareness, Knowledge, Attitude and Practice of Radiation Hazards and Radiation Protection among the Undergraduate Dental Students in C.S.M.S.S Dental College and Hospital, Chh. Sambhajinagar- A Questionnaire Based Cross-sectional Study

Awareness, Knowledge, Attitude and Practice of Radiation Hazards and Radiation Protection among the Undergraduate Dental Students in C.S.M.S.S Dental College and Hospital, Chh. Sambhajinagar- A Questionnaire Based Cross-sectional Study

Beyond labs: unveiling dynamics of dental students' transition from pre-clinical to clinical training in a Saudi dental school.

To assess the factors affecting the transition of dental students from pre-clinical to clinical courses in an outcome-based curriculum. This cross-sectional study surveyed dental students in the third and fourth academic years of the Bachelor of Dental and Oral Surgery (BDS) program at the College of Dentistry, Jouf University. Ethically approved and powered by the G Power software, the study employed a modified questionnaire validated through a pilot test to assess five domains. Likert scale responses were analyzed using SPSS v.25, revealing insights into clinical workload, patient interaction, and learning experiences. Multiple regression analysis was used to assess the impact of clinical skill application, workload, transition to clinics, and patient interaction on learning experience as well as CGPA. The Mann-Whitney U test compared the ranks of two independent samples, making it less sensitive to outliers and more suitable for data with non-normal distributions. In this study, the response rate of the participants was 70%. A total of 44 dental students in their third and fourth years of the program completed the survey. The multiple regression analysis showed that the predictors collectively explained 36.1% of the variance in the learning experience (Adjusted R2 = 0.361). "Transition to Clinics" had a significant positive effect on learning experience (β = 0.292, p = 0.012), "Workload" (β = -0.203, p = 0.393) and "Patient Interaction" (β = 0.443, p = 0.168) were not significant predictors. The Mann-Whitney U test revealed no significant gender differences in transition to clinics, workload, patient interaction, application of clinical skills, and learning experience (U = 33.09 to -40.33, p > 0.05), but a significant difference in transition to clinics between third- and fourth-year students (U = 31.56 to -43.24, p < 0.05). The results of this study demonstrate that the transition to clinical training can be intricate, and that multiple elements have an impact on this process. It is crucial to have support systems that facilitate the transition into the clinical learning environment.

Effect of different mouthwash solutions on the surface morphology, nanohardness and flexural modulus of nickel-titanium orthodontic wire.

This laboratory study aimed to evaluate the effect of different mouthwash solutions on the surface and mechanical properties of NiTi arch wire. This experimental study was conducted at the Department of Preventive Dental Sciences, College of Dentistry, Princess Nourah bint Abdulrahman University, Saudi Arabia from September 2023 to November 2023. A 30 mm NiTi wires in length with 0.017 × 0.022" in dimensions were selected and equally divided into four groups: Control (G0) group wires were immersed in distilled water (DW); G1 wires were immersed in antiseptic mouthwash; G2 wires were immersed in fluoridated mouthwash; and G3 wires were immersed in therapeutic mouthwash. Surface morphology, nanohardness, and flexural modulus were evaluated at 24-hours, four weeks, and eight weeks' time points. Data were statistically analyzed using a two-way analysis of variance (P<0.05). The arch wires immersed in DW showed insignificant effects on surface roughness, nanohardness, and flexural modulus at different time points. However, all the experimental groups showed a significant effect of time and immersion solutions on the said properties (P<0.05). At the end of eight weeks, G3 showed the highest surface roughness (0.346 ± 0.032 µm) and the lowest nanohardness (1.350 ± 0.412 GPa) and flexural modulus (3.960 ± 0.140 MPa) compared to other study groups. The efficiency of tooth realignment could be influenced by the detrimental influence of fluoride and hydrogen peroxide mouthwash solutions on superelastic NiTi arch wires.

Iron overload and liver function in patients with beta thalassemia major: A cross sectional study.

In thalassemia major, repeated blood transfusions result in iron overload causing organ damage. The objective of this study was assessment of liver enzymes in patients with Thalassemia major and to observe their association with ferritin. A cross-sectional study was performed, at Islamabad Medical and Dental College and its affiliated Akbar Niazi Teaching Hospital from November 2021 till August 2022. Serum ferritin, AST, ALT, and total bilirubin levels were determined, in 135 patients of beta thalassemia major receiving transfusions. Data analysis was performed using SPSS Version 20. For categorical variables, calculation of frequencies and percentages was performed. Mean (± standard deviation) was determined for quantitative variables. ANOVA with post hoc Tukey's test was used for determining association between liver enzymes and serum ferritin. A p-value of <0.05 was considered significant. The correlation between ferritin and LFTs was determined by Pearson's correlation coefficient. Patients had an age range of 7-30 years, and males constituted 51% of sample. Mean level of ferritin was 6062.61 + 3641.79 ng/ml, with an insignificant difference between the genders (p =0.366). The levels of AST, ALT and bilirubin were perceived to show a significant increase in patients with ferritin levels >5000ng/ml, when compared with patients having ferritin levels < 2,500 ng/ml. A significant positive correlation of increasing serum ferritin levels was observed with ALT (r= 0.682), to a lesser extent with AST (r = 0.532), and only a weak correlation with serum bilirubin (r = 0.350). Liver damage was caused by increased iron deposition. LFTs should be performed regularly to detect and reduce liver damage by increasing chelation therapy, thereby reducing morbidity and mortality due to thalassemia.

Evaluation of Knowledge about Epilepsy among Undergraduate Health Students: A Cross-Sectional Study

Abstract Background Greater knowledge of undergraduate health students will provide quality care to patients with epilepsy. Most previous studies have targeted teachers, health care providers, and the general public. The purpose of this study was to assess the knowledge gaps of undergraduate health students on basic subjects of epilepsy, such as etiologies, symptoms, and treatment options. Methods Our study conducted a cross-sectional survey among undergraduate health students. We collected data using a descriptive information form. The chi-square test was employed to compare knowledge of seizure between demographic and academic variables. Results Of the total, 84.4% of students had read or heard about epilepsy. However, only 2.8% of students displayed good knowledge scores toward epilepsy. About 18.2 and 32% of students incorrectly identified that epilepsy could be due to possession by evil spirits and blood disorder, respectively. More than half of the students considered epilepsy to be nontreatable (52.1%) and a contagious disease (55.4%). Moreover, students in the advanced age group, medicine, and clinical years displayed significantly better knowledge scores than their peers (p &lt; 0.05). All dental college students revealed poor scores in terms of knowledge about epilepsy's causes, symptoms, and treatment. Conclusion Our findings concluded that most undergraduate health students demonstrated poor knowledge scores regarding epilepsy. Notably, students studying in dental college and preclinical years had a lower understanding of epilepsy than their peers. This finding suggests that introducing comprehensive epilepsy education in all health-related courses could improve patient care.

Awareness to Orthodontics among a Sample of Final Year Dental Students

Abstract Objective Because of esthetic demand, awareness about orthodontic treatment has increased nowadays, especially among young people and adolescents, in addition to the fact that knowledge of orthodontics and various details of it is more significant among dental students according to what they learned in their curricula and their examination and observation of many cases of malocclusion. The objective of the present study was to evaluate the awareness of the final year of undergraduate dental students toward orthodontics. Materials and Methods About 532 (320 females and 212 males) students in the fifth year of six Iraqi universities were invited to participate in this questionnaire distributed via the Google classroom. This questionnaire included 20 questions about orthodontics. Pearson's chi-square test evaluated the gender and universities differences. Results In general, the awareness responses were very high in most of the questions answered except in three questions in which the percentage of positive answers varies from 49 to 76%. Also, there were no significant gender differences in 17 question answers, and only 3 showed significant gender differences. Females expressed a high level of awareness than males. Conclusion The high and close level of awareness expressed by students' responses in this study revealed the integrated education in orthodontic sciences in Iraqi dental colleges in different universities, except in some questions that deal with topics about the acceleration of tooth movement and the relation between vitamin D3 and teeth movement.

Insights into research activities of senior dental students in the Middle East: A multicenter preliminary study

BackgroundDespite the increasing recognition of the importance of research in undergraduate dental education, limited studies have explored the nature of undergraduate research activities in dental schools in the Middle East region. This study aimed to evaluate the research experience of final year dental students from three dental schools in the Middle East.MethodsA descriptive, cross-sectional study was conducted among final-year dental students from three institutions, namely Jordan University of Science and Technology, University of Sharjah (UAE), and Oman Dental College. Participants were asked about the nature and scope of their research projects, the processes involved in the research, and their perceived benefits of engaging in research.Results A total of 369 respondents completed the questionnaire. Cross-sectional studies represented the most common research type (50.4%), with public health (29.3%) and dental education (27.9%) being the predominant domains. More than half of research proposals were developed via discussions with instructors (55.0%), and literature reviews primarily utilized PubMed (70.2%) and Google Scholar (68.5%). Regarding statistical analysis, it was usually carried out with instructor’s assistance (45.2%) or using specialized software (45.5%). The students typically concluded their projects with a manuscript (58.4%), finding the discussion section most challenging to write (42.0%). The research activity was considered highly beneficial, especially in terms of teamwork and communication skills, as well as data interpretation skills, with 74.1% of students reporting a positive impact on their research perspectives.ConclusionsThe research experience was generally positive among surveyed dental students. However, there is a need for more diversity in research domains, especially in qualitative studies, greater focus on guiding students in research activities s, especially in manuscript writing and publication. The outcomes of this study could provide valuable insights for dental schools seeking to improve their undergraduate research activities.

Clinical and Radiographic Evaluation of Soft Tissue and Bone Status in Immediate Loaded Implants Placed Following Their Extraction in the Maxillary Anterior Region.

In the maxillary anterior region, teeth extraction leads to significant soft and hard tissue changes. Immediate implant placement following extraction aims to reduce bone loss and overall treatment time. However, it may result in adverse soft tissue changes impacting esthetics. This study evaluates the clinical and radiographic outcomes of immediately loaded implants in the maxillary anterior region, focusing on soft tissue preservation and bone status. This study, conducted from April 2022 to August 2024 at the Department of Oral and Maxillofacial Surgery, Ragas Dental College and Hospital, included 10 immediately loaded implants in seven patients. Following atraumatic extraction, implants were placed and loaded with functional provisional crowns fabricated using three-dimensional (3D) rapid prototyping models. Parameters such as crestal bone loss, buccal and palatal bone width, and interdental papilla thickness were evaluated preoperatively and postoperatively using radiographsand clinical assessments. The study found significant crestal bone loss at both mesial and distal sites over time, with the greatest loss observed at the three-month follow-up. Buccal and palatal bone width showed no significant differences preoperatively and postoperatively. Interdental papilla thickness and overall pink esthetic scores also showed no significant differences between preoperative and postoperative evaluations. Immediate implant placement in the maxillary anterior region, using 3D rapid prototyping for custom splint fabrication, demonstrated effective preservation of soft tissue profile and bone architecture. This approach provides functional and esthetic benefits, although careful monitoring of crestal bone loss is necessary.