Degree Of Complementarity Research Articles

Global Networks, Local Specialisation and Regional Patterns of Innovation

A large academic consensus exists on the idea that successful innovative processes are geographically bounded within regions. Nevertheless, the ability of regions to capture and re-use external knowledge is also regarded as a fundamental element to sustain and refine the local profile of specialisation and competitiveness. The present article combines these views to investigate the sources of the regional innovation process, by analysing data on Italian regions over the period 2007-2012. We define regional external networks based on all the foreign subsidiaries of local multinational enterprises identifiable as global ultimate owners. Our main results suggest that both the internal specialisation and the outward networks can generate indigenous innovation, but the role of the networks varies substantially according to its density, its degree of complementarity with the specialisation profile, its geographical spread and the specific location of the foreign subsidiaries. Our results, then, support a view of the regional innovation as an interactive process whereby valuable knowledge resources are not only generated within the reach of the local economy, but they are also integrated with external inputs. This contrasts with recent anti-globalisation views according to which the increase in the foreign operations of national companies impoverishes the local economy.

Bioinformatic identification of euploid and aneuploid embryo secretome signatures in IVF culture media based on MALDI-ToF mass spectrometry.

Embryo genotyping in IVF clinics aims to identify aneuploid embryos, and current methodologies rely on costly, invasive and time-consuming approaches such as PGT-A screening. MALDI-ToF-based mass spectral analysis of embryo culture has been demonstrated to be a non-invasive, affordable and accurate technique that is able to capture secretome profiles from embryo culture media extremely quick. Thus, aneuploid embryo genotypes can be distinguished from euploids from these profiles towards the development of novel embryo selection tools. A retrospective cohort study, including 292 spent media samples from embryo cultures collected from a single IVF clinic in USA. There were 149 euploid and 165 aneuploid embryos previously analysed by PGT-A next-generation sequencing techniques. Secretome mass spectra of embryos were generated using MALDI-ToF mass spectrometry in the UK. Data was systematically analysed using a fully automated and ultra-fast bioinformatic pipeline developed for the identification of mass spectral signatures. Distinct spectral patterns were found for euploid and aneuploid genotypes in embryo culture media. We identified 12 characteristic peak signatures for euploid and 17 for aneuploid embryos. Data analysis also revealed a high degree of complementarity among regions showing that 22 regions are required to differentiate between genotypes with a sensitivity of 84% and a false positive rate of 18%. Ultra-fast and fully automated screening of an embryo genotype is possible based on multiple combinations of specific mass spectral peak signatures. This constitutes a breakthrough towards the implementation of non-invasive and ultra-fast tools for embryo selection immediately prior to transfer.

Analysis of public policy formulation and its effect on the technical and professional work of the community psychologist: A case study.

The academic and professional relationship between Community Psychology and public policy is increasing, especially as pertaining to social issues. An important discussion is to be had regarding the complexity, degrees of complementarity, and contributions of this link, as well as its risks for the discipline of Community Psychology. In this context, this study asks the following question: What are the dynamics of public policy formulation for extreme poverty in Chile and its effect on the technical definition of the psychologists' work, and what alternatives this opens up for a discussion on the relationship between Community Psychology and public policies? A qualitative and idiographic methodological approach is used, based on Grounded Theory by Strauss & Corbin (2002) and the Case Study by Coller (2000), to analyze semistructured interviews with 10 policymakers of the Chile Seguridades y Oportunidades policy and nine legislative and technical documents that support this policy. The results show that the technical work of the psychologist who participates in public policy towards extreme poverty is affected and configured by the mechanisms and dynamics of the connection between the various frameworks of meaning of policy formulation. These frames of meaning affect the configuration of technical norms that, in a dynamic of reciprocal influence between notions of reference, notions of problem and notions of solution, affect and configure the professional tasks of the psychologists, in terms of the focus of their work, their objectives, levels of intervention and interdisciplinary work.

COMPLEMENTARITY BETWEEN TANGIBLE AND INTANGIBLE CAPITAL: EVIDENCE FROM JAPANESE FIRM-LEVEL DATA

Using Japanese firm-level panel data spanning from 2000 to 2013, we estimate industry-level production functions that explicitly take into account the complementarity and substitutability between tangible and intangible capital. The estimation results show that tangible and intangible capitals are complementary in most industries although the degree of complementarity substantially varies across industries. We further find that the relation between tangible and intangible capital in the production function accounts for the relation between firm-level tangible capital and intangible capital investments. Namely, firms’ tangible investments are more strongly positively associated with intangible investments as the degree of the complementarity between the tangible and intangible assets becomes larger. These findings show the necessity to take into account the relation between the dynamics of tangible and intangible capital in terms of their complementarity for precisely understanding the mechanisms governing a firm’s growth.

Immigration and Employment: Substitute Versus Complementary Labor in Selected African Countries

This paper uses census and household survey data on Cameroon, Ghana, and South Africa to examine immigration’s impact in the context of a segmented labor market in Sub-Saharan Africa. We find that immigration affects (i) employment (ii) employment allocation between informal and formal sectors, and (iii) the type of employment within each sector. The direction of the impact depends on the degree of complementarity between immigrants and native workers’ skills. Immigration is found to be productivity-enhancing in the short to near term in countries where, the degree of complementarity between immigrants and native workers’ skill sets is the highest.

Top-Down Characterization of an Intact Monoclonal Antibody Using Activated Ion Electron Transfer Dissociation.

Monoclonal antibodies (mAbs) are important therapeutic glycoproteins, but their large size and structural complexity make them difficult to rapidly characterize. Top-down mass spectrometry (MS) has the potential to overcome challenges of other common approaches by minimizing sample preparation and preserving endogenous modifications. However, comprehensive mAb characterization requires generation of many, well-resolved fragments and remains challenging. While ETD retains modifications and cleaves disulfide bonds-making it attractive for mAb characterization-it can be less effective for precursors having high m/z values. Activated ion electron transfer dissociation (AI-ETD) uses concurrent infrared photoactivation to promote product ion generation and has proven effective in increasing sequence coverage of intact proteins. Here, we present the first application of AI-ETD to mAb sequencing. For the standard NIST mAb, we observe a high degree of complementarity between fragments generated using standard ETD with a short reaction time and AI-ETD with a long reaction time. Most importantly, AI-ETD reveals disulfide-bound regions that have been intractable, thus far, for sequencing with top-down MS. We conclude AI-ETD has the potential to rapidly and comprehensively analyze intact mAbs.

Pricing Decisions on Online Channel Entry for Complementary Products in a Dominant Retailer Supply Chain

This study considered the supply chain that two manufacturers sell green complementary products to a dominant offline retailer. We investigated whether a manufacturer (the integrated manufacturer) should add an online channel and examined how it affects channel members’ decisions and profits. We formulated the power structure as the retailer-Stackelberg model and analyzed the pricing decisions for the supply chain. The results demonstrate that the integrated manufacturer prefers not to add the online channel when online and offline market bases are comparable and the level of complementarity is moderate. The integrated manufacturer gains more power at the expense of the offline retailer and the other manufacturer (the traditional manufacturer) when the complementarity between the offline and online channel is the same as offline channels with the addition of a new online channel; furthermore, the retailer earns less, while the traditional manufacturer’s profit hinges on the complementarity between the online and offline channels. It is beneficial for the offline retailer to balance the online and offline market bases of product 1 by improving the sales environment of the physical store. The integrated manufacturer can benefit from varying their marketing actions to decrease the degree of complementarity between the retail and online channels for the two products, while the traditional manufacturer can be better off from the online channel introduction by taking steps to increase the complementarity of the two products between the offline channels.

Global networks, local specialisation and regional patterns of innovation

A large academic consensus exists on the idea that successful innovative processes are geographically bounded within regions. Nevertheless, the ability of regions to capture and re-use external knowledge is also regarded as a fundamental element to sustain and refine the local profile of specialisation and competitiveness. The present article combines these views to investigate the sources of the regional innovation process, by analysing data on Italian regions over the period 2007–2012. We define global networks based on all the local firms identifiable as global ultimate owners and their foreign subsidiaries. Our main results suggest that both the internal specialisation and the regional external linkages can generate indigenous innovation, but the role of the networks varies substantially according to its density, its degree of complementarity with the specialisation profile, its geographical spread and the specific location of the foreign subsidiaries. Our results, then, support a view of the regional innovation as an interactive process whereby valuable knowledge resources are not only generated within the reach of the local economy, but they are also integrated with external inputs. This contrasts with recent anti-globalisation views according to which the increase in the foreign operations of national companies impoverishes the local economy.

The Demand for the Characteristics of Football Matches: A Hedonic Price Approach

We estimate a system of demand equations for three aggregate characteristics of a football game—quality of the teams, outcome uncertainty, and schedule—based on the estimation of a hedonic price model for the ticket price of a football match using data from the Spanish football league. We conclude that all three characteristics are not inferior goods (quality as a luxury), and they are price inelastic, showing some degree of complementarity. Some implications of these results in terms of the measures taken and to be taken by the Spanish association of football clubs (LaLiga) are discussed.

LA COMPLEMENTARIEDAD ENTRE EL MÉTODO DE ENSEÑANZA DE SINTAXIS TRADICIONAL E INVERSO EN 3º DE E.S.O.

El presente trabajo analiza dos métodos de enseñanza de sintaxis aplicados en Educación Secundaria: la sintaxis tradicional y la sintaxis inversa. Del estudio de ambos métodos se deduce su complementariedad y su necesidad mutua a la hora de ponerlos en práctica. Así, el objetivo fundamental del trabajo es estudiar cómo se comportan los dos métodos en un aula de 3º E.S.O. y añadir un componente lúdico a su enseñanza que motive a los alumnos y los lleve hacia una mejora de los resultados. Además, para corroborar todo ello se recoge una muestra empírica en el Centro I.E.S. Rosa Navarro (Olula del Río, Almería) en 3º de E.S.O. Una vez analizados los datos, se proponen una serie de conclusiones que dejan patente el grado de complementariedad que puede existir entre ambos métodos de enseñanza. This document analyses two teaching syntax methods applied to Secondary Education: the traditional syntax and the inverse syntax. From the study of these two methodologies, their complementarity and mutual necessity are deduced when putting them into practise. In this way, the main objectives of this research are to study how these two methods work in a 3rd ESO class and to add a playful component to their learning processes that motivate the students so they can get an improvement on their results. Also, in order to confirm all these, an empirical sample is collected from the Secondary Education High School called Rosa Navarro (Olula del Río, Almería) in the 3rd year of ESO. Once the data are analysed, some conclusions are proposed in order to establish the degree of complementarity existing between the two mentioned teaching methods.

Effect of species diversity on particle clearance and productivity in farmed bivalves

Most bivalve farms are designed as monocultures, yet diverse communities often outperform monocultures in various metrics of ecosystem functioning, including particle clearance and productivity. This study tested the feasibility of bivalve polyculture by examining particle clearance, growth, and survival of 4 species that are economically important to the northeastern USA. Three particle depletion experiments were conducted to determine if more diverse bivalve assemblages had greater clearance rates than those which were less diverse. Different assemblages of Crassostrea virginica, Spisula solidissima, Mercenaria mercenaria, and Mya arenaria were supplied with a single cultured algal species, a mix of 2 cultured algal species, or natural seston. To determine how species richness affects bivalve productivity, growth and survival were monitored in a flow-through mesocosm experiment, which simulated farm conditions. In the cultured algae experiments, more diverse assemblages did not exhibit significantly greater clearance rates than those that were less diverse. Instead, the clearance rates of each species were additive across assemblages. Surprisingly, most assemblages did not display a significant preference for the larger microalgae species, Pavlova lutheri (4.0-6.0 µm), over Nannochloropsis oculata (1.90-3.75 µm). Most notably, when supplied with natural seston, the 4-species polyculture demonstrated a significantly greater tank-level clearance rate for particles <25 µm compared to most monocultures. However, nearly all productivity metrics were not significantly affected by species richness. This work suggests that some degree of complementarity exists among these bivalves, and that in non-food limited systems, these bivalves could be co-cultured without outcompeting one another.

Integrating risk into control system design: The complementarity between risk-focused results controls and risk-focused information sharing

In this study, I investigate how firms design risk-focused control practices to embed risk considerations in employee decision making. The firm’s objective is to make sure that employee behavior is aligned with firm risk appetite. To investigate how firms go about this control problem, I consider the use of risk-focused results controls (i.e., expanding results controls by risk aspects). Despite the advantages of jointly managing risk and performance through risk-focused results controls, prior literature indicates that their isolated use has also some drawbacks. Recent research hints at the crucial role of risk culture in this regard. In a next step, I present risk-focused information sharing as tangible and manageable dimension of risk culture that alleviates the weaknesses of risk-focused results controls while leaving the benefits of the latter intact. I also posit that risk-focused results controls make risk-focused information sharing more effective. Drawing on complementarity theory, I argue theoretically and show empirically that there is a complementarity between risk-focused results controls and risk-focused information sharing irrespective of the level of risk appetite a firm displays. Furthermore, I identify firm risk appetite as a system-specific contextual variable that drives the degree of complementarity between the two risk-focused control practices. Consistent with my prediction, the results indicate that the complementarity between risk-focused results controls and risk-focused information sharing is significantly stronger for firms displaying a high level of risk appetite. Using data from a survey of 202 companies, I find empirical support for my hypotheses.

A bundling sales strategy for a two-stage supply chain based on the complementarity elasticity of imperfect complementary products

PurposeThis paper attempts to analyze the relationship between the complementarity degrees of imperfect complementary products and sales strategies and give appropriate sales strategies for a two-stage supply chain.Design/methodology/approachWith respect to two-stage supply chain consisting of two manufacturers who produce imperfect complementary products and one retailer who sells the products, aiming at bundling sales strategy, the authors define complementarity elasticity of products and use it to measure the degree of complementary between two products. Based on Stackelberg game and cooperation, the authors analyze the relationship between the complementarity degrees of imperfect complementary products and appropriate sales strategies.FindingsAs the impact of complementarity degree on sales strategy decision-making is better, the authors can pinpoint out which sales decision-making is optimal and which bundling sales strategy is the best for a two-stage supply chain. Considering that the degree of complementarity has a significant impact on the product sales strategy, the authors can point out which sales decision-making is optimal, that is, which bundled sales strategy is the optimal in the secondary supply chain of selling complementary products.Practical implicationsAn innovative bundling can expand the sales of existing products and new products. It helps a retailer transcend and defeat competitors by reducing marketing expenses while increasing profits. Proper use of bundling can improve consumers utility and create an overall positive effect for both the enterprises and consumer.Originality/valueThe research can help some retailers to make many appropriate bundling sales strategies.

Privatization of a multi-product public firm

ABSTRACT This study considers a public firm that provides a profitable service and an unprofitable service. In our model, only the public firm supplies the unprofitable service, while both the public firm and multiple private firms supply the profitable service. The two services may be substitutes, complements, or independent in demand, and the public firm has inferior technology. We examine whether the public firm should privatize either the profitable service or the service that faces competition from private firms. We obtain the following results. When the two services are complementary, the critical cost of the public firm such that privatizing the profitable service is socially preferable increases with the degree of complementarity. When the two services are substitutes, the critical cost decreases (increases) with the degree of substitution for a low (high) degree of substitution. For a sufficiently high degree of substitution, the critical cost becomes small.

The complementarity of multiculturalism and interculturalism: theory backed by Australian evidence

ABSTRACT The decline of multiculturalism as a public discourse has been caused by various socio-political factors – such as 9/11 and its aftermath and the growth in migration – and new pro- and anti-diversity isms have been offered instead. One such pro-diversity discourse is interculturalism. Whilst some of its advocates, especially in Quebec and Europe, have seen it as a replacement of multiculturalism, a closer examination shows a high degree of complementarity. We demonstrate this by a theoretical-normative unpacking of multiculturalism and of the claims of interculturalism, and by evidence that Australian publics see multiculturalism as supportive of interculturalism, perceived as a renewal of multiculturalism. We express the hope that the sometimes oppositional debate between these two isms may now move forward into a phase of complementarity.

Thorough Performance Evaluation of 213 nm Ultraviolet Photodissociation for Top-down Proteomics

Top-down proteomics studies intact proteoform mixtures and offers important advantages over more common bottom-up proteomics technologies, as it avoids the protein inference problem. However, achieving complete molecular characterization of investigated proteoforms using existing technologies remains a fundamental challenge for top-down proteomics. Here, we benchmark the performance of ultraviolet photodissociation (UVPD) using 213 nm photons generated by a solid-state laser applied to the study of intact proteoforms from three organisms. Notably, the described UVPD setup applies multiple laser pulses to induce ion dissociation, and this feature can be used to optimize the fragmentation outcome based on the molecular weight of the analyzed biomolecule. When applied to complex proteoform mixtures in high-throughput top-down proteomics, 213 nm UVPD demonstrated a high degree of complementarity with the most employed fragmentation method in proteomics studies, higher-energy collisional dissociation (HCD). UVPD at 213 nm offered higher average proteoform sequence coverage and degree of proteoform characterization (including localization of post-translational modifications) than HCD. However, previous studies have shown limitations in applying database search strategies developed for HCD fragmentation to UVPD spectra which contains up to nine fragment ion types. We therefore performed an analysis of the different UVPD product ion type frequencies. From these data, we developed an ad hoc fragment matching strategy and determined the influence of each possible ion type on search outcomes. By paring down the number of ion types considered in high-throughput UVPD searches from all types down to the four most abundant, we were ultimately able to achieve deeper proteome characterization with UVPD. Lastly, our detailed product ion analysis also revealed UVPD cleavage propensities and determined the presence of a product ion produced specifically by 213 nm photons. All together, these observations could be used to better elucidate UVPD dissociation mechanisms and improve the utility of the technique for proteomic applications.

Regional analysis of wind velocity patterns in complex terrain

Wind energy is a weather and climate-dependent energy resource with natural spatio-temporal variabilities at time scales ranging from fraction of seconds to seasons and years, while at spatial scales it is strongly affected by the terrain and vegetation. To optimize wind energy systems and maximize the energy extraction, wind measurements on various time scales as well as wind energy forecasts are required and needed. This study focuses on spatio-temporal characteristics of the wind velocity in complex terrain, relevant to wind energy assessment, operation, and grid integration, using data collected at 11 towers ranging from 40 to 80 m tall over a 12-year period in complex terrain of western-central and northern Nevada, USA. The autocorrelation analysis, Detrended Fluctuation Analysis (DFA) and Detrended Cross-Correlation Analysis (DCCA) showed strong coherence between the wind speed and direction with slowly decreasing amplitude of the multi-day periodicity with increasing lag periods. Besides pronounced diurnal periodicity at all locations, statistical analysis and DFA also showed significant seasonal and annual periodicities, long-memory persistence with similar characteristics at all sites and towers with a relatively narrow range of the Weibull parameters. The DCCA indicates similar wind patterns at each tower, and strong correlations between measurement sites in spite of separations of about 300 km across the towers’ setup. The northern Nevada area exhibits higher wind resource potential and higher wind persis-tence compared to the western-central region. Overall, the DFA and DCCA results suggest higher degree of complementarity among wind data at measure-ment sites compared to previous standard statistical analysis.

A model of a team contest, with an application to incentives under list proportional representation

We develop a model of a team contest for multiple, indivisible prizes. Team members exert costly effort to improve their team's success. We analyze two intrateam allocation rules. Under a list rule, prizes are allocated according to a predetermined list. Under an egalitarian rule, prizes are allocated according to a fair lottery. We show that which allocation rule maximizes team success depends on the degree of complementarity between members' efforts and the convexity of the individual cost of effort function. We then apply the model to the context of elections under proportional representation with both open and closed lists. We derive conditions under which closed lists generate stronger incentives than open lists. Our results offer a rationale for the lack of evidence on the negative incentive effects of closed lists.

The role of complementarity of goods in a mixed bundling strategy

This paper studies optimal pricing when a monopolist firm produces two complementary goods and may undertake a bundling strategy. To do so, a modified version of Yan and Bandyopadhyay’s (2011) framework is used, in which the efficacy of the bundling strategy depends positively on the degree of complementarity of goods. Two main results are obtained. First, mixed bundling turns out to be the optimal strategy for the firm, since it yields higher profits than pure unbundling and pure bundling. Second, sales and profits from the bundling (unbundling) strategy increase (decrease) as the products become more complementary, which entails an empirically sensible behavior.

Cocktails done right: price competition and welfare when substitutes become complements

In this paper we analyze the effects of the introduction (by either firms or authorities) of a composite good consisting of a fixed proportion of two imperfectly substitutable stand-alone products. First, we find that such a “cocktail” rises the Bertrand equilibrium prices as it introduces a certain degree of complementarity. It also creates incentives to price discriminate and products can be sold at a discount or at a premium (depending on their degree of substitutability) when they are used as part of the composite good. We consider two distinct forms of price discrimination: a traditional one, in which producers set their prices independently of each other and a coordinated one, in which producers cooperate (collude) when setting the price of the composite good. Composite goods might have either a positive or a negative impact on consumer surplus. The sign of the impact depends on the form of price discrimination and consumers tend to be better off if producers coordinate. The impact is also more likely to be positive if “cocktails are done right”, i.e., if their quality is high compared to the quality of the stand-alone products.