Repeated clinical use of arch wires requires sterilization and may result in alteration of the properties of the wires as they get subjected to corrosion and cold working. Therefore, the present study aimed to assess the effects of different clinical recycling methods on the load-deflection properties of super-elastic and thermal nickel-titanium orthodontic arch wires. A total of 50 0.014" round nickel-titanium orthodontic wires [Group I: super-elastic nickel-titanium (n = 25) and Group II: thermal nickel-titanium wires (n = 25)] were tested for changes in their load deflection properties after three different recycling methods, that is, dry heat sterilization, autoclave, and cold sterilization. For each group, five wires as received from the manufacturer were taken as control (T0), and the rest of the 20 wires were placed intra-orally for a duration of one cycle of clinical use (T1). Five wires out of these were subjected to 3-point bending tests, and the rest of the wires were subjected to different recycling methods. Load deflection properties of recycled wires were measured with an Instron universal testing machine. The results were tabulated, and the data were analyzed by analysis of variance (ANOVA) with the Tukey post hoc test. Statistically, no significant difference was found in the super-elastic group between samples recycled by dry heat, autoclave, and cold sterilization when compared with as-received super-elastic NiTi up to 2.5 mm of deflection. A highly significant difference was found between as-received thermal NiTi group (83.51 ± 6.49 N/mm) and samples recycled by dry heat (53.73 ± 4.72 N/mm), autoclave (45.38 ± 4.37 N/mm), and cold sterilization (48.44 ± 3.12 N/mm) at 0.5 mm of deflection. Among thermal NiTi, any of the sterilization methods could opt at all deflections. For super-elastic NiTi, at higher deflections or in cases of crowding of more than 2.5 mm, cold sterilization should be the method of choice, whereas any sterilization method can be used at deflections less than 2.5 mm.