To analyze the influence of different ignition positions on the propagation of deflagration characteristics and the disaster mechanism in the hydrogen deflagration process in the tunnel, this study compares and verifies the experimental data of tunnel model deflagration based on the CFD code GASFLOW-MPI. A combustion velocity model based on the accelerated separation effect is used, and the effect of heat transfer on the consequences of deflagration is considered. The propagation laws of pressure waves, fluid velocity and temperature in the tunnel are analyzed, and it is found that the changing trends of shock waves and fluid velocity in the tunnel are consistent, but completely opposite in the tunnel outside. The effects of different ignition positions on the hydrogen deflagration characteristics are compared and analyzed. The results show that when ignition occurs at different heights of the center of the premixed region, the impact on the deflagration characteristics is relatively small, while when ignition occurs at different horizontal distances in the premixed region, the impact on the deflagration characteristics is relatively large; the peak overpressure of side ignition is far lower than the case where ignition occurs in the center of the premixed region, but the maximum flow velocity is much higher than the center ignition. The impact on temperature is the smallest. In general, in areas close to the hydrogen/air premixed zone, side ignition results in more severe consequences, whereas in areas far from the premixed zone and outside the tunnel, central ignition leads to more severe consequences. This study provides theoretical support for understanding the disaster-causing mechanisms of hydrogen/air premixed gas deflagration in tunnels under different ignition positions.