The study of iron concentration effect on the oxide glass structure has shown evidence of depolymerization of the vitreous network with increasing iron content and especially with Fe2+ amount for all types of glass. For all glass compositions studied, we observe by EPR a blockage of defects creation processes under β irradiation for glasses doped with more than 1 wt% of Fe2O3. Reduction processes of Fe3+ under irradiation is also detected. Moreover for sodalime glass samples, β irradiation induces depolymerization, in opposite of what was expected and observed for other glasses. Anyway, adding iron up to 4 wt% Fe2O3 always diminishes the β irradiation effects. This has been linked to the observed iron reduction and to the ability of iron, maybe coupled with charge trapping processes to consume excitons.