Deep Learning System Research Articles

A domain knowledge-based interpretable deep learning system for improving clinical breast ultrasound diagnosis.

Though deep learning has consistently demonstrated advantages in the automatic interpretation of breast ultrasound images, its black-box nature hinders potential interactions with radiologists, posing obstacles for clinical deployment. We proposed a domain knowledge-based interpretable deep learning system for improving breast cancer risk prediction via paired multimodal ultrasound images. The deep learning system was developed on 4320 multimodal breast ultrasound images of 1440 biopsy-confirmed lesions from 1348 prospectively enrolled patients across two hospitals between August 2019 and December 2022. The lesions were allocated to 70% training cohort, 10% validation cohort, and 20% test cohort based on case recruitment date. Here, we show that the interpretable deep learning system can predict breast cancer risk as accurately as experienced radiologists, with an area under the receiver operating characteristic curve of 0.902 (95% confidence interval = 0.882 - 0.921), sensitivity of 75.2%, and specificity of 91.8% on the test cohort. With the aid of the deep learning system, particularly its inherent explainable features, junior radiologists tend to achieve better clinical outcomes, while senior radiologists experience increased confidence levels. Multimodal ultrasound images augmented with domain knowledge-based reasoning cues enable an effective human-machine collaboration at a high level of prediction performance. Such a clinically applicable deep learning system may be incorporated into future breast cancer screening and support assisted or second-read workflows.

Deep Learning and High-Resolution Anoscopy: Development of an Interoperable Algorithm for the Detection and Differentiation of Anal Squamous Cell Carcinoma Precursors-A Multicentric Study.

High-resolution anoscopy (HRA) plays a central role in the detection and treatment of precursors of anal squamous cell carcinoma (ASCC). Artificial intelligence (AI) algorithms have shown high levels of efficiency in detecting and differentiating HSIL from low-grade squamous intraepithelial lesions (LSIL) in HRA images. Our aim was to develop a deep learning system for the automatic detection and differentiation of HSIL versus LSIL using HRA images from both conventional and digital proctoscopes. A convolutional neural network (CNN) was developed based on 151 HRA exams performed at two volume centers using conventional and digital HRA systems. A total of 57,822 images were included, 28,874 images containing HSIL and 28,948 LSIL. Partial subanalyses were performed to evaluate the performance of the CNN in the subset of images acetic acid and lugol iodine staining and after treatment of the anal canal. The overall accuracy of the CNN in distinguishing HSIL from LSIL during the testing stage was 94.6%. The algorithm had an overall sensitivity and specificity of 93.6% and 95.7%, respectively (AUC 0.97). For staining with acetic acid, HSIL was differentiated from LSIL with an overall accuracy of 96.4%, while for lugol and after therapeutic manipulation, these values were 96.6% and 99.3%, respectively. The introduction of AI algorithms to HRA may enhance the early diagnosis of ASCC precursors, and this system was shown to perform adequately across conventional and digital HRA interfaces.

Pneumonia Detection Using Deep Learning

Lung disease called pneumonia is brought on by a bacterial infection. An effective treatment plan heavily depends on an early diagnosis. An expert radiologists can typically diagnose the condition with a chest x-ray. For several reasons, including the emergence of an illness that is not visible on a chest x-ray or the possibility that it is mistaken for another ailment, the diagnosis may be arbitrary. Thus, to assist clinicians, automated diagnostic technologies are required. In this work, a deep learning system for picture classification the Convolutional Neural Networks algorithm was constructed on a dataset. Chest radiographs are included in the data set, and the created model is assessed using a few statistical factors. Key Words: Diagnosis, computer-aided, deep learning, pneumonia, convolution neural networks, mass chest x-ray, chest x-ray14.

Remote Measurement of Tide and Surge Using a Deep Learning System with Surveillance Camera Images

The latest progress in deep learning approaches has garnered significant attention across a variety of research fields. These techniques have revolutionized the way marine parameters are measured, enabling automated and remote data collection. This work centers on employing a deep learning model for the automated evaluation of tide and surge, aiming to deliver accurate results through the analysis of surveillance camera images. A mode of deep learning based on the Inception v3 structure was applied to predict tide and storm surges from surveillance cameras located in two different coastal areas of Italy. This approach is particularly advantageous in situations where traditional tide sensors are inaccessible or distant from the measurement point, especially during extreme events that require accurate surge measurements. The conducted experiments illustrate that the algorithm efficiently measures tide and surge remotely, achieving an accuracy surpassing 90% and maintaining a loss value below 1, evaluated through Categorical Cross-Entropy Loss functions. The findings highlight its potential to bridge the gap in data collection in challenging coastal environments, providing valuable insights for coastal management and hazard assessments. This research contributes to the emerging field of remote sensing and machine learning applications in environmental monitoring, paving the way for enhanced understanding and decision-making in coastal regions.

A deep learning system for the detection of optic disc neovascularization in diabetic retinopathy using optical coherence tomography angiography images

A deep learning system for the detection of optic disc neovascularization in diabetic retinopathy using optical coherence tomography angiography images

Impact of Transfer Learning Using Local Data on Performance of a Deep Learning Model for Screening Mammography.

Purpose To investigate the issues of generalizability and replication of deep learning models by assessing performance of a screening mammography deep learning system developed at New York University (NYU) on a local Australian dataset. Materials and Methods In this retrospective study, all individuals with biopsy or surgical pathology-proven lesions and age-matched controls were identified from a South Australian public mammography screening program (January 2010 to December 2016). The primary outcome was deep learning system performance-measured with area under the receiver operating characteristic curve (AUC)-in classifying invasive breast cancer or ductal carcinoma in situ (n = 425) versus no malignancy (n = 490) or benign lesions (n = 44). The NYU system, including models without (NYU1) and with (NYU2) heatmaps, was tested in its original form, after training from scratch (without transfer learning), and after retraining with transfer learning. Results The local test set comprised 959 individuals (mean age, 62.5 years ± 8.5 [SD]; all female). The original AUCs for the NYU1 and NYU2 models were 0.83 (95% CI: 0.82, 0.84) and 0.89 (95% CI: 0.88, 0.89), respectively. When NYU1 and NYU2 were applied in their original form to the local test set, the AUCs were 0.76 (95% CI: 0.73, 0.79) and 0.84 (95% CI: 0.82, 0.87), respectively. After local training without transfer learning, the AUCs were 0.66 (95% CI: 0.62, 0.69) and 0.86 (95% CI: 0.84, 0.88). After retraining with transfer learning, the AUCs were 0.82 (95% CI: 0.80, 0.85) and 0.86 (95% CI: 0.84, 0.88). Conclusion A deep learning system developed using a U.S. dataset showed reduced performance when applied "out of the box" to an Australian dataset. Local retraining with transfer learning using available model weights improved model performance. Keywords: Screening Mammography, Convolutional Neural Network (CNN), Deep Learning Algorithms, Breast Cancer Supplemental material is available for this article. © RSNA, 2024 See also commentary by Cadrin-Chênevert in this issue.

Human versus Artificial Intelligence: Validation of a Deep Learning Model for Retinal Layer and Fluid Segmentation in Optical Coherence Tomography Images from Patients with Age-Related Macular Degeneration.

Artificial intelligence (AI) models have received considerable attention in recent years for their ability to identify optical coherence tomography (OCT) biomarkers with clinical diagnostic potential and predict disease progression. This study aims to externally validate a deep learning (DL) algorithm by comparing its segmentation of retinal layers and fluid with a gold-standard method for manually adjusting the automatic segmentation of the Heidelberg Spectralis HRA + OCT software Version 6.16.8.0. A total of sixty OCT images of healthy subjects and patients with intermediate and exudative age-related macular degeneration (AMD) were included. A quantitative analysis of the retinal thickness and fluid area was performed, and the discrepancy between these methods was investigated. The results showed a moderate-to-strong correlation between the metrics extracted by both software types, in all the groups, and an overall near-perfect area overlap was observed, except for in the inner segment ellipsoid (ISE) layer. The DL system detected a significant difference in the outer retinal thickness across disease stages and accurately identified fluid in exudative cases. In more diseased eyes, there was significantly more disagreement between these methods. This DL system appears to be a reliable method for accessing important OCT biomarkers in AMD. However, further accuracy testing should be conducted to confirm its validity in real-world settings to ultimately aid ophthalmologists in OCT imaging management and guide timely treatment approaches.

MULTIMODAL SYSTEM FOR FACIAL EMOTION RECOGNITION BASED ON DEEP LEARNING

Emotions are one of the main ways of communication between people and of expressing attitudes towards objects, products, services, etc. They are divided to verbal and non-verbal classes. Human speech and intonation belong to the first class, and to the second (non-verbal) facial and body emotions, known as body language. The subject of this report is the development of multimodal deep learning system intended to recognize facial and body emotions and their relationship with the scene (weather) in which they occur. It is based on three deep learning neural networks (DNN) each one for recognition of facial emotion, body emotion and weather. Combining their results, we improve significantly the final facial emotion recognition (FER) results.

Combining enhanced spectral resolution of EMG and a deep learning approach for knee pathology diagnosis.

Knee osteoarthritis (OA) is a prevalent, debilitating joint condition primarily affecting the elderly. This investigation aims to develop an electromyography (EMG)-based method for diagnosing knee pathologies. EMG signals of the muscles surrounding the knee joint were examined and recorded. The principal components of the proposed method were preprocessing, high-order spectral analysis (HOSA), and diagnosis/recognition through deep learning. EMG signals from individuals with normal and OA knees while walking were extracted from a publicly available database. This examination focused on the quadriceps femoris, the medial gastrocnemius, the rectus femoris, the semitendinosus, and the vastus medialis. Filtration and rectification were utilized beforehand to eradicate noise and smooth EMG signals. Signals' higher-order spectra were analyzed with HOSA to obtain information about nonlinear interactions and phase coupling. Initially, the bicoherence representation of EMG signals was devised. The resulting images were fed into a deep-learning system for identification and analysis. A deep learning algorithm using adapted ResNet101 CNN model examined the images to determine whether the EMG signals were conventional or indicative of knee osteoarthritis. The validated test results demonstrated high accuracy and robust metrics, indicating that the proposed method is effective. The medial gastrocnemius (MG) muscle was able to distinguish Knee osteoarthritis (KOA) patients from normal with 96.3±1.7% accuracy and 0.994±0.008 AUC. MG has the highest prediction accuracy of KOA and can be used as the muscle of interest in future analysis. Despite the proposed method's superiority, some limitations still require special consideration and will be addressed in future research.

Power load forecasting based on spatial–temporal fusion graph convolution network

The cyclical behavior of electricity users facilitates the prediction of future electricity loads through the analysis of historical data, in addition to considering the spatial correlation among various electricity units. Building on these observations, this study transforms the power loads generated by regional-level user units into graph signals for a more effective visualization of spatial–temporal electricity consumption patterns. Specifically, the graph-based model harnesses its unique spatial–temporal dependencies to deduce the dynamics of electricity consumption patterns and enhance the precision of electricity generation predictions. Introducing a novel deep learning model, the Spatial-Temporal Fusion Graph Convolutional Network (FSTGRNN), which integrates temporal and spatial correlations for the prediction of electricity load values at future time steps. FSTGRNN is an end-to-end model that, firstly, delineates the spatial and temporal patterns of electric loads by constructing spatial relationship graphs using the FC-LSTM and GC-GRU models designed within the spatial–temporal block (ST-Block). Secondly, the spatial–temporal fusion block (STF-Block) in FSTGRNN, equipped with a gating mechanism, encodes the graph signals to capture both long-term dependencies and short-term correlations. The resulting integrated representation is utilized for the forecasting process. Experimental validation is conducted on two electricity load datasets, and the forecasting results clearly demonstrate the superiority and efficiency of the proposed deep learning system.

Classification of Intracranial Hemorrhage (CT) Images Using CNN- LSTM Method and Image-Based GLCM Features

In this study, a hybrid approach is utilized, which combines image-based grey-level co-occurrence matrix attributes and transformed-based attributes. The combination of attribute-based techniques is more accurate in categorizing cerebral hemorrhages in CT images when compared with the transformed attribute-based and image-attribute-based approaches. Deep learning methods, particularly long short-term memory (LSTM), have gained popularity in natural language processing applications like text and sentiment analysis. This paper presents an in-depth deep-learning system that is fully automated. The purpose of the system is to organize radiological data and identify cases of intracranial hemorrhage (ICH) for diagnosis. The structure of the proposed DL model includes 1D convolution neural networks (CNN), long short-term memory (LSTM) units, and a logistic function. A significant dataset consisting of 12,852 radiological reports of head computed tomography (CT) was used to train and assess these components.

Abstract PO4-07-03: Machine learning breast cancer risk prediction using sequential past mammograms - a pilot study

Abstract Background and Aim Some studies have reported the use of mammogram AI deep learning algorithms to accurately predict the risk of future breast cancer development in women. In these studies, random and unrelated mammograms were independently used for training of the AI model. We propose a novel deep learning system using sequential past mammograms instead of random studies and aimed to determine if it can further improve risk prediction in a pilot study. Methods Pre-training of the backbone of a Swin-transformer machine learning model was performed by applying region-of-interest lesional masks of benign and malignant on a training set of 1644 mammograms derived from the open-access Curated Breast Imaging Subset of Digital Database for Screening Mammography dataset. To further develop the model, deep learning training and validation were performed on the Cohort of Screen-age Women (CSAW) open-access screening mammogram set which was derived from the long term data of 873 women who developed breast cancer for the first time and 7850 non-cancer women. We then compared the diagnostic accuracy of a model using sequential past mammograms for training against the standard, non-sequential model. For the sequential model, imaging segmentation of the potential cancer site on mammography was performed on all past, pre-cancer mammograms obtained within 60 to 2555 days of cancer diagnosis in the pre-processing stage for breast cancer cases. AI training was then carried out by combining the pre-cancer mammograms belonging to the same woman in a temporal sequence using a transformer encoder. The learning rate started from 1e-6 and decayed 10 times every 10 epochs. For the non-sequential model, we removed the temporal encoder and used random, unrelated mammogram studies for training. Validation was performed on a dataset consisting of 75 pre-cancer mammograms from breast cancer cases and 69 mammograms from non-cancer cases. Results Sensitivity, specificity and overall accuracy on the validation set were 77.3% (58/75), 68.1% (47/69) and (105/144) 72.9% respectively for the sequential model compared to 69.3% (52/75), 69.6% (48/69) and 69.4% (100/144) respectively for the non-sequential model. Conclusion The study showed that deep learning breast cancer risk prediction can be further improved by using sequential past mammograms instead of random mammograms for AI model training. This can also potentially enhance other AI risk prediction models that employ combined mammogram and traditional breast cancer clinical risk factors. A larger validation study will be useful. Contact information: email Lester Leong at lester.leong.c.h@singhealth.com.sg ROC curve for breast cancer risk prediction using AI deep learning training with sequential past mammograms. Citation Format: Lester Leong, Mingjie Xu, Weimin Huang, Erli Zhang, Engracia Loh, Sze Yiun Teo, Geok Hoon Lim, Veronique Kiak Mien Tan, Yirong Sim, Fredrik Strand, Ryan Tan. Machine learning breast cancer risk prediction using sequential past mammograms - a pilot study [abstract]. In: Proceedings of the 2023 San Antonio Breast Cancer Symposium; 2023 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2024;84(9 Suppl):Abstract nr PO4-07-03.

Deep learning system for screening AIDS-related cytomegalovirus retinitis with ultra-wide-field fundus images

BackgroundOphthalmological screening for cytomegalovirus retinitis (CMVR) for HIV/AIDS patients is important to prevent lifelong blindness. Previous studies have shown good properties of automated CMVR screening using digital fundus images. However, the application of a deep learning (DL) system to CMVR with ultra-wide-field (UWF) fundus images has not been studied, and the feasibility and efficiency of this method are uncertain. MethodsIn this study, we developed, internally validated, externally validated, and prospectively validated a DL system to detect AIDS-related from UWF fundus images from different clinical datasets. We independently used the InceptionResnetV2 network to develop and internally validate a DL system for identifying active CMVR, inactive CMVR, and non-CMVR in 6960 UWF fundus images from 862 AIDS patients and validated the system in a prospective and an external validation data set using the area under the curve (AUC), accuracy, sensitivity, and specificity. A heat map identified the most important area (lesions) used by the DL system for differentiating CMVR. ResultsThe DL system showed AUCs of 0.945 (95 % confidence interval [CI]: 0.929, 0.962), 0.964 (95 % CI: 0.870, 0.999) and 0.968 (95 % CI: 0.860, 1.000) for detecting active CMVR from non-CMVR and 0.923 (95 % CI: 0.908, 0.938), 0.902 (0.857, 0.948) and 0.884 (0.851, 0.917) for detecting active CMVR from non-CMVR in the internal cross-validation, external validation, and prospective validation, respectively. Deep learning performed promisingly in screening CMVR. It also showed the ability to differentiate active CMVR from non-CMVR and inactive CMVR as well as to identify active CMVR and inactive CMVR from non-CMVR (all AUCs in the three independent data sets >0.900). The heat maps successfully highlighted lesion locations. ConclusionsOur UWF fundus image-based DL system showed reliable performance for screening AIDS-related CMVR showing its potential for screening CMVR in HIV/AIDS patients, especially in the absence of ophthalmic resources.

Harnessing TME depicted by histological images to improve cancer prognosis through a deep learning system

Spatial transcriptomics (ST) provides insights into the tumor microenvironment (TME), which is closely associated with cancer prognosis, but ST has limited clinical availability. In this study, we provide a powerful deep learning system to augment TME information based on histological images for patients without ST data, thereby empowering precise cancer prognosis. The system provides two connections to bridge existing gaps. The first is the integrated graph and image deep learning (IGI-DL) model, which predicts ST expression based on histological images with a 0.171 increase in mean correlation across three cancer types compared with five existing methods. The second connection is the cancer prognosis prediction model, based on TME depicted by spatial gene expression. Our survival model, using graphs with predicted ST features, achieves superior accuracy with a concordance index of 0.747 and 0.725 for The Cancer Genome Atlas breast cancer and colorectal cancer cohorts, outperforming other survival models. For the external Molecular and Cellular Oncologycolorectal cancer cohort, our survival model maintains a stable advantage.

A novel approach for identification of zoonotic trypanosome utilizing deep metric learning and vector database-based image retrieval system

Trypanosomiasis, a significant health concern in South America, South Asia, and Southeast Asia, requires active surveys to effectively control the disease. To address this, we have developed a hybrid model that combines deep metric learning (DML) and image retrieval. This model is proficient at identifying Trypanosoma species in microscopic images of thin-blood film examinations. Utilizing the ResNet50 backbone neural network, a trained-model has demonstrated outstanding performance, achieving an accuracy exceeding 99.71 % and up to 96 % in recall. Acknowledging the necessity for automated tools in field scenarios, we demonstrated the potential of our model as an autonomous screening approach. This was achieved by using prevailing convolutional neural network (CNN) applications, and vector database based-images returned by the KNN algorithm. This achievement is primarily attributed to the implementation of the Triplet Margin Loss function as 98 % of precision. The robustness of the model demonstrated in five-fold cross-validation highlights the ResNet50 neural network, based on DML, as a state-of-the-art CNN model as AUC >98 %. The adoption of DML significantly improves the performance of the model, remaining unaffected by variations in the dataset and rendering it a useful tool for fieldwork studies. DML offers several advantages over conventional classification model to manage large-scale datasets with a high volume of classes, enhancing scalability. The model has the capacity to generalize to novel classes that were not encountered during training, proving particularly advantageous in scenarios where new classes may consistently emerge. It is also well suited for applications requiring precise recognition, especially in discriminating between closely related classes. Furthermore, the DML exhibits greater resilience to issues related to class imbalance, as it concentrates on learning distances or similarities, which are more tolerant to such imbalances. These contributions significantly make the effectiveness and practicality of DML model, particularly in in fieldwork research.

Integration of eye-tracking and object detection in a deep learning system for quality inspection analysis

Abstract During quality inspection in manufacturing, the gaze of a worker provides pivotal information for identifying surface defects of a product. However, it is challenging to digitize the gaze information of workers in a dynamic environment where the positions and postures of the products and workers are not fixed. A robust, deep learning-based system, ISGOD (Integrated System with worker’s Gaze and Object Detection), is proposed, which analyzes data to determine which part of the object is observed by integrating object detection and eye-tracking information in dynamic environments. The ISGOD employs a six-dimensional pose estimation algorithm for object detection, considering the location, orientation, and rotation of the object. Eye-tracking data were obtained from Tobii Glasses, which enable real-time video transmission and eye-movement tracking. A latency reduction method is proposed to overcome the time delays between object detection and eye-tracking information. Three evaluation indices, namely, gaze score, accuracy score, and concentration index are suggested for comprehensive analysis. Two experiments were conducted: a robustness test to confirm the suitability for real-time object detection and eye-tracking, and a trend test to analyze the difference in gaze movement between experts and novices. In the future, the proposed method and system can transfer the expertise of experts to enhance defect detection efficiency significantly.

Assessment of the deep learning-based gamma passing rate prediction system for 1.5 T magnetic resonance-guided linear accelerator.

Measurement-based verification is impossible for the patient-specific quality assurance (QA) of online adaptive magnetic resonance imaging-guided radiotherapy (oMRgRT) because the patient remains on the couch throughout the session. We assessed a deep learning (DL) system for oMRgRT to predict the gamma passing rate (GPR). This study collected 125 verification plans [reference plan (RP), 100; adapted plan (AP), 25] from patients with prostate cancer treated using Elekta Unity. Based on our previous study, we employed a convolutional neural network that predicted the GPRs of nine pairs of gamma criteria from 1%/1mm to 3%/3mm. First, we trained and tested the DL model using RPs (n=75 and n=25 for training and testing, respectively) for its optimization. Second, we tested the GPR prediction accuracy using APs to determine whether the DL model could be applied to APs. The mean absolute error (MAE) and correlation coefficient (r) of the RPs were 1.22 ± 0.27% and 0.29 ± 0.10 in 3%/2mm, 1.35 ± 0.16% and 0.37 ± 0.15 in 2%/2mm, and 3.62 ± 0.55% and 0.32 ± 0.14 in 1%/1mm, respectively. The MAE and r of the APs were 1.13 ± 0.33% and 0.35 ± 0.22 in 3%/2mm, 1.68 ± 0.47% and 0.30 ± 0.11 in 2%/2mm, and 5.08 ± 0.29% and 0.15 ± 0.10 in 1%/1mm, respectively. The time cost was within 3s for the prediction. The results suggest the DL-based model has the potential for rapid GPR prediction in Elekta Unity.

Robust Intelligent Malware Detection Using Deep Learning

Abstract: In the modern era of technology, malicious software, or malware, holds a serious security hazard as computer users, businesses, and governments see an uptick in malware attacks. In attempts to identify unknown malware, current malware detection solutions use dynamic as well as static examination of malware signatures and behavior patterns, which takes time and is unsuccessful. Modern malware employs evasive strategies such as metamorphosis and polymorphism to rapidly alter its actions and produce a multitude of variants. Machine learning algorithms (MLAs) are being used more and more to do an efficient malware analysis because new malware is primarily versions of current malware. Extensive feature engineering, feature learning, and feature representation are needed for this. It is likely to fully eliminate the feature engineering stage by utilizing sophisticated MLAs like deep learning. Even though there have been a few fresh investigations in the field, the algorithms' performance is skewed by the training set. It is a prerequisite to reduce bias and figure out these techniques holistically in order to develop new, improved techniques for successful zero-day malware detection. This paper fills a vacuum in the literature by comparing and contrasting deep learning architectures with standard MLAs for malware detection, classification, and categorization using public and private datasets. The public and private dataset’s train and test splits, which were gathered during distinctly different periods, are not connected to one another in the experimental study. Furthermore, we provide a new method of image processing with ideal parameters for deep learning architectures and MLAs. In response to a thorough scientific assessment of these methodologies, deep learning architectures perform more efficiently than traditional MLAs. All in all, our work suggests a scalable and multimodal deep learning system for real-time malware detection through visual means. An improved technique for successful zero-day malware detection is the visualization and deep learning architectures for static, dynamic, and image processing based blended methods in a big data environment.

Deep learning approach for cardiovascular disease risk stratification and survival analysis on a Canadian cohort.

The quantification of carotid plaque has been routinely used to predict cardiovascular risk in cardiovascular disease (CVD) and coronary artery disease (CAD). To determine how well carotid plaque features predict the likelihood of CAD and cardiovascular (CV) events using deep learning (DL) and compare against the machine learning (ML) paradigm. The participants in this study consisted of 459 individuals who had undergone coronary angiography, contrast-enhanced ultrasonography, and focused carotid B-mode ultrasound. Each patient was tracked for thirty days. The measurements on these patients consisted of maximum plaque height (MPH), total plaque area (TPA), carotid intima-media thickness (cIMT), and intraplaque neovascularization (IPN). CAD risk and CV event stratification were performed by applying eight types of DL-based models. Univariate and multivariate analysis was also conducted to predict the most significant risk predictors. The DL's model effectiveness was evaluated by the area-under-the-curve measurement while the CV event prediction was evaluated using the Cox proportional hazard model (CPHM) and compared against the DL-based concordance index (c-index). IPN showed a substantial ability to predict CV events (p < 0.0001). The best DL system improved by 21% (0.929 vs. 0.762) over the best ML system. DL-based CV event prediction showed a ~ 17% increase in DL-based c-index compared to the CPHM (0.86 vs. 0.73). CAD and CV incidents were linked to IPN and carotid imaging characteristics. For survival analysis and CAD prediction, the DL-based system performs superior to ML-based models.

Stock Market Prediction and Analysis using Supervised Learning

The Stock Market Remains a Captivating Subject for Stockbrokers and Investors Seeking Financial Success Through Strategic Equity Trading. Informed Decisions Are Pivotal in Navigating the Dynamic Landscape of Stock Investments, Prompting the Adoption of Various Predictive Techniques. This Study Introduces a Novel Prediction Algorithm That Elucidates the Intricate Relationship Between Independent Variables—Comprising Opening and Closing Prices, High and Low Stock Values, and Trading Volume—and the Dependent Variable, Which Is the Stock Price. Leveraging a Deep Learning System, We Demonstrate the Efficacy of Generating Precise Stock Price Forecasts. Our Research Ambit Encompasses a Comprehensive Exploration of Diverse Deep-Learning Architectures Tailored to Anticipate Stock Prices for Global Conglomerates and Indian Enterprises. A Primary Objective Is to Conduct a Comparative Analysis of These Architectures, Discerning Their Respective Performances in Stock Price Prediction Scenarios. Notably, Long Short-Term Memory (Lstm) Algorithms Are Instrumental in Achieving Heightened Accuracy and Robust Prediction Outcomes. The Methodology Entails Meticulous Data Collection From Historical Stock Market Datasets Spanning Various Companies of Global and Indian Origin. Subsequent Data Preprocessing Involves Addressing Missing Values, Standardizing Features, and Structuring the Data Into Sequences Conducive to Lstm Model Input. The Lstm Architecture, Characterized by Its Adeptness in Capturing Long-Term Dependencies and Temporal Patterns, Forms the Cornerstone of Our Prediction Model. Through This Research Endeavor, We Aim to Provide Valuable Insights Into the Potential of Deep Learning Algorithms, Particularly Lstm, in Facilitating Informed Decision-Making for Investors and Stock Market Participants