This study evaluates the quality and vulnerability of groundwater within the Nakivale Sub-catchment of the transboundary Lake Victoria Basin in Southwestern Uganda. Groundwater quality assessment focuses on its suitability for both drinking and agricultural uses. Hydrochemical analysis of 19 groundwater samples revealed that 90% comply with World Health Organization drinking water standards, although localized contamination was noted, particularly in terms of total iron, nitrate, potassium, magnesium, and sulfates. The drinking groundwater quality index shows that over 90% of the samples fall within the good-to-excellent quality categories. Elevated nitrate levels and chloride–bromide ratios indicate human impacts, likely due to agricultural runoff and wastewater disposal. For irrigation, Sodium Adsorption Ratio analysis revealed medium-to-high salinity hazards in the region, while Sodium Percentage and other parameters indicated low-to-moderate risks of soil degradation. DRASTIC vulnerability assessments identified low contamination risks due to impermeable geological layers, steep terrain, slow groundwater recharge, deep aquifer depth, and clayey soil cover. These findings emphasize the need for conjunctive water resource management, including improved groundwater quality monitoring, public education on sustainable practices, and protective measures for recharge zones and areas highly susceptible to contamination. By addressing these issues, this study aims to preserve groundwater resources for domestic and agricultural use, ensuring long-term sustainability in the region.
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