Well loss and its accompanying reservoir damage is a common and serious problem, which not only greatly restricts the economic benefit, but also seriously affects the correct evaluation of reservoir oil and gas resources in the early stage of exploration. With the exploration and development of deep Marine carbonate oil and gas resources, fracture leakage has gradually become a frontier and hot issue to be studied urgently. Foreign scholars began to study the leakage model of fractured reservoir in the 1990s, but at present, domestic scholars mainly focus on the clastic rock model, focusing on the plugging technology and plugging materials, while ignoring the importance of the dynamic development of the leakage indirectly reflecting the leakage type and the size of the leakage channel. This paper comprehensively analyses the effects of drilling completion fluid rheology, fracture opening variation, fracture wall filtration and other factors on well loss from the time sequence of the establishment of the leakage model, summarizes the research progress of the mathematical model of leakage in fractured reservoirs, and proposes to pay attention to and strengthen the monitoring of the leakage mechanism and the dynamic process of leakage, so as to provide a theoretical basis for the rapid diagnosis of leakage types and the optimization of leakage control.