The stability of GFRP tube-confined UHPC-filled steel-encased columns (FUSCs) is critical for optimal utilization of its superior cross-sectional load-bearing capacity that guarantees overall structural safety. This study conducted an experimental investigation on 14 slender FUSC specimens under uniaxial compression for different aspect ratios and aggregate contents. The pressure-sensing films were applied to measure the contact pressure between the GFRP tube and UHPC, and a mesoscale finite element model was developed to uncover the role of randomly distributed fibers and aggregates in the UHPC during the failure process. Accordingly, the stability performance of slender FUSC was analyzed, and specific discussions were held on the mutual interaction mechanism between GFRP and UHPC during the loading process. The results showed that the stability of FUSCs decreased faster with an aspect ratio of l0/D > 8 (λ>30.77), resulting in the decrease of load-carrying capacity for up to 25 %. By including coarse aggregate, the distribution of steel fibers was densified, and Young's Modulus of UHPC was increased, considerably improving the stability of FUSCs. Moreover, the GFRP tube with a fixed winding angle of 50° remarkably enhanced the stability of the specimen due to the sharing of bending moment instead of providing confinement. This research outcome offers a basis for the stability control of slender FUSCs.