Decrease In Velocity Research Articles

The Effect of Allogeneic Hematopoietic Stem Cell Transplantation on Sickle Cell Disease-Related Organ Damage: A Systematic Review and Meta-Analysis

Background Allogeneic hematopoietic stem cell transplantation (HSCT) is the only established curative treatment option for patients with sickle cell disease (SCD). One of the main indications for HSCT is SCD-related organ damage, which is a major cause of morbidity and early mortality. However, whether HSCT is effective in recovering SCD-related organ dysfunction has not been systematically reviewed. Methods This is a systematic review and meta-analysis investigating the effects of HSCT on organ function in patients with SCD. We performed a comprehensive search in MEDLINE/PubMed and EMBASE up to June 2023, focusing on studies reporting pulmonary, cardiac, renal, splenic, and/or cerebral function parameters, as well as retinopathy and/or avascular osteonecrosis (AVN) before and after HSCT. Continuous data were analyzed using the weighted inverse-variance random effects meta-analyses, reported as standardized mean difference (SMD) and 95% confidence intervals (95%-CI). Binomial data were analyzed using the Mantel-Haenszel random effects meta-analyses, reported as risk ratio (RR) and 95%-CI. A negative SMD indicates an improvement and a positive SMD indicates a worsening of the measured parameter post-HSCT. A RR <1 indicates a result in favor of the transplantation and a RR >1 indicates a worsening of the measured parameter after HSCT. The ‘Newcastle-Ottawa Quality Assessment Scale’ and the ‘Clinical Diversity in Meta-analysis’ (CDIM) tool were used to assess the quality and the clinical heterogeneity of the studies. Results Thirty-two of 476 studies met our inclusion criteria, of which 17 were used for the meta-analyses and 15 for the qualitative part of the review. Of the studies that were included in the meta-analyses, 4 comprised adult patients (n=184) and 13 pediatric and/or young adults <22 years old (n=591). The majority of donors were matched sibling donors (86.4%), and studies with both myeloablative and/or reduced intensity conditioning regimens were included. The CDIM score was low or moderate for all performed meta-analyses, suggesting fair clinical comparability among the studies. Summary plots of the meta-analyses are shown in Figure 1. Pulmonary function test parameters remained stable following HSCT (SMD -0.08, p=0.64 for forced expiratory volume in 1 second; SMD -0.13, p=0.35 for forced vital capacity; and SMD -0.95, p=0.30 for diffusing capacity). Mean tricuspid regurgitation velocity (TRV) did not change significantly in the meta-analysis (SMD -0.34, p=0.14). However, 3 studies used for the qualitative review reported normalization in patients with prior elevated TRV. Whole brain cerebral blood flow improved significantly after transplantation (SMD -1.39, p=<0.01). Several studies reported an absent or very low incidence of new (silent) cerebral infarcts and a decrease of transcranial Doppler velocities following successful HSCT. In pediatric patients, creatinine clearance decreased significantly after HSCT (SMD -0.80, p=0.01) and the presence of proteinuria increased (RR 2.00, p=<0.01). Furthermore, splenic uptake ( 99mTc) and phagocytic function of the spleen improved (RR 0.31, p=<0.01 and RR 0.23, p=<0.01, respectively). Retinopathy and AVN before and after HSCT were investigated in only 1 study in children with SCD, both showing no significant changes post-HSCT. Discussion and Conclusion Allogeneic HSCT has the potential to stabilize or recover pulmonary and cardiac function parameters in SCD patients. In pediatric patients, splenic function parameters showed impressive improvement following HSCT. On the other hand, creatinine clearance decreased significantly in children. This might be a reflection of either normalization of SCD-related hyperfiltration or transplantation-related toxicity, which may also have contributed to the increased prevalence of proteinuria after HSCT. With respect to cerebral damage, cerebral perfusion parameters improved and progression of silent cerebral infarctions was prevented following HSCT. Last, we demonstrate a paucity of evidence regarding the course of renal function, retinopathy, and AVN in adult SCD transplant recipients. More research is needed to define which patients with SCD-related organ damage might benefit most from HSCT and which organs are less likely to recover.

An experimental study of steam turbulent jet condensation & upward propagation of thermal plume into sub-cooled water pool

Supersonic steam’s axial injection into water in a cylindrical vessel (1 m high and 24 cm in diameter) was achieved through a nozzle of 6 mm diameter, located at the center of the vessel. Optical examinations were determined through a steam jet to find out condensation rate, which was allied with the steam mass flux (295–672 kg/m2/s) while leaving the nozzle’s exit. The Reynolds number (i.e., 41,000–73,610) has been estimated based on most swollen section of the steam’s jet. Further beyond the condensation zone, the steam, that has been condensed, progresses into a condensed steam plume, which is surrounded by the sub-cooled water. Particle Image Velocimetry (PIV) has been applied to focus region through the mid axis of the heated water plume along a vertical plane of 100 mm × 100 mm cross sections till 400 mm from the nozzle. Central upward averaged velocity profile of the condensed water thermal plume has been evaluated at 295 and 672 kg/m2s, both have hinted the exponential decrease of mean axial velocity when the plume travels vertically upward. The radial velocity distribution of the mean axial velocity across the radial dispersal of the jet, has been obtained as self-preservable and the mean axial velocity attained the Gaussian profile by incorporating appropriate grading of axial distance and mean velocity. Other significant aspect of the current work is to apply the buoyant scaling evolved from the single-phase non-condensing upward thermal plumes to the condensed upward plume through the relations of volume flow, momentum and buoyant being computed from the steam jet operating conditions. The source values of physical dimensionless parameters such as Reynolds number (Reo), Plume Richardson number (Ripo), entrainment coefficient (αo), buoyant vertical scale (Bo) have been evaluated. Based on the radial spread of the velocity profiles along the vertical distance from the condensation region, the dynamics of the thermal and the jet propagation has been highlighted through the evaluation of the dimensionless buoyant parameters along the downstream of the plume. The present experimental measurements obtained for condensed single-phase plume are compared with the experimental results of the non-condensed single-phase thermal plume to signify the vitality of the dimensionless parameters derived from non-condensed plumes.

Transdimensional ambient-noise surface wave tomography of the Reykjanes Peninsula, SW Iceland

SUMMARY Ambient noise seismic tomography has proven to be an effective tool for subsurface imaging, particularly in volcanic regions such as the Reykjanes Peninsula (RP), SW Iceland, where ambient seismic noise is ideal with isotropic illumination. The primary purpose of this study is to obtain a reliable shear wave velocity model of the RP, to get a better understanding of the subsurface structure of the RP and how it relates to other geoscientific results. This is the first tomographic model of the RP which is based on both on- and off-shore seismic stations. We use the ambient seismic noise data and apply a novel algorithm called one-step 3-D transdimensional tomography. The main geological structures in the study area (i.e. covered by seismic stations) are the four NE–SW trending volcanic systems, orientated highly oblique to the plate spreading on the RP. These are from west to east; Reykjanes, Eldvörp-Svartsengi, Fagradalsfjall and Krýsuvík, of which all except Fagradalsfjall host a known high-temperature geothermal field. Using surface waves retrieved from ambient noise recordings, we recovered a 3-D model of shear wave velocity. We observe low-velocity anomalies below these known high-temperature fields. The observed low-velocity anomalies below Reykjanes and Eldvörp-Svartsengi are significant but relatively small. The low-velocity anomaly observed below Krýsuvík is both larger and stronger, oriented near-perpendicular to the volcanic system, and coinciding well with a previously found low-resistivity anomaly. A low-velocity anomaly in the depth range of 5–8 km extends horizontally along the whole RP, but below the high-temperature fields, the onset of the velocity decrease is shallower, at around 3 km depth. This is in good agreement with the brittle–ductile transition zone on the RP. In considerably greater detail, our results confirm previous tomographic models obtained in the area. This study demonstrates the potential of the entirely data-driven, one-step 3-D transdimensional ambient noise tomography as a routine tomography tool and a complementary seismological tool for geothermal exploration, providing an enhanced understanding of the upper crustal structure of the RP.

Investigation of the effects of nasal surgery on nasal cavity flow using magnetic resonance velocimetry and computational fluid dynamics

The nasal cavity has the function of conditioning the air inhaled into the lungs by heating, humidifying, and filtering dust and virus-borne aerosols. Analyzing the flow field in the nasal cavity is vital because its function is strongly related to flow dynamics. Due to experimental limitations posed by the complex internal geometry of the nasal cavity, most previous studies have utilized Reynolds averaged Navier–Stokes based computational fluid dynamics (CFD) simulations. In this study, the flow field in a post-operative nasal cavity was evaluated using not only CFD simulations but also four-dimensional magnetic resonance velocimetry. The study was conducted under resting breathing conditions in pre- and post-operative models of a patient who received septoplasty and turbinoplasty. The experimental results confirmed balanced flow rates in the left and right nasal cavities after septoplasty and a decrease in velocity after turbinoplasty with a reduction in regions with vortices and reverse flow. Upon comparison, CFD results using the laminar, k–ω, and shear stress transport models were deemed to be consistent with the experimental results. However, there was a relatively large deviation observed with the k–ε model. Using the validated laminar CFD model, it was shown that the pressure and wall shear stress decreased after surgery.

Induced-charge electroosmosis flow of viscoelastic fluids under different voltage arrangements

Efficient mixing of chemical analysis reagents with laboratory samples at a microscale is a key issue in numerous biomedical and chemical analyses but hardly to implement due to the limited of the low diffusivity in laminar flow. Induced-charge electroosmosis flow, as an innovative mixing method, has been proved to be effective and simple in rapid mixing attributes to its mechanism of vortex generation. This work aims to propose a new strategy for chaotic induced-charge electroosmosis flow based on different voltage arrangements to improve the mixing of viscoelastic fluids. The Phan–Thien–Tanner constitutive model is applied to characterize the flow behavior of viscoelastic fluid in a microfluidic preparation mixer. The direct numerical simulation method is used to solve the fully coupled Navier–Stokes and Poisson–Nernst–Planck equations for a polarizable cylinder in a two-dimensional cavity filled with electrolyte solution. The impact of Weissenberg number (Wi), Debye parameter, voltage strength on the velocity, net charge density, and potential profiles is investigated. The simulation results indicate that a greater Wi leads to the decrease in the maximum velocity, and a large voltage strength can heighten the net charge density and potential, thus improve the peak velocity. Moreover, the classical theoretical prediction that the maximum velocity is proportional to the square of the applied voltage has been authenticated.

Viscoelectric effect on the chemiosmotic flow in charged soft nanochannels

The charged nanochannel surface and pH-sensitive grafted polyelectrolyte layer (PEL) play a critical role in the design of devices aimed at controlling nanofludic flow. They enable the manipulation of ionic transport by influencing the electric-double (EDL) layers that overlap. Additionally, the viscoelectric effect, amplified by a strong EDL electric field, may enhance the activation energy and viscosity of liquids. Motivated by this, we conducted a numerical investigation using a finite element method-based solver, COMSOL, to examine the effects of the viscoelectric effect on concentration-gradient-driven chemiosmotic flow in a charged soft nanochannel with grafted pH-sensitive polyelectrolyte layer on the inner wall surfaces. It is important to note that the nanochannel is positioned between two reservoirs with different pH values and bulk-ionic concentrations. The PEL is sensitive to protonic association–dissociation due to the presence of carboxylic and amine groups in monomeric units. In our study, we comprehensively demonstrate variations in key variables characterizing the underlying flow. These variations include changing the solute concentration in the left side reservoir within the range of 0.1–5 mol m−3, adjusting the pH of the right-side reservoir (pHR) within the range of 3–10, and varying the viscoelectric coefficient. The viscoelectric effect significantly raises viscosity near the wall due to the stronger EDL electric field generated at the left-side reservoir resulting from the higher solute concentration. On the other hand, viscosity tends to decrease with lower pHR values and remains unaffected by changes at higher pHR values. The average flow velocity shows an increasing–decreasing pattern as the concentration of the right-side reservoir is enhanced. Additionally, the decrease in flow velocity becomes noticeably more pronounced with higher solute concentrations in the right-side reservoir when accounting for the viscoelectric effect. The findings of the present study have practical implications for novel nanofluidic devices, frequently employed in various engineering applications to control flow.

Levenberg–Marquardt neural network-based intelligent computation for the non-Newtonian polymer during forward roll coating

Scientists and researchers widely recognize the effectiveness of artificial intelligence (AI)-based machine learning and intelligent computing solvers, demonstrating qualities such as resilience, robustness, stability, and rapid convergence. One particularly significant and rapidly growing field within AI is artificial neural networks. This research uses a supervised neural network model based on Levenberg–Marquardt backpropagation (LMB-SNNs) to examine the Sisko fluid model for the forward roll coating process (SFM-FRCP). A suitable transformation is applied to the partial differential equations based SFM-FRCP mathematical model, resulting in a set of nonlinear ordinary differential equations. The perturbation method has been used to find the analytical solutions for the velocity profile, pressure gradient, and pressure profile. A dataset for varying the pertinent parameters is generated, and the LMB-SNNs technique has been used to estimate the velocity profile, pressure gradient, and pressure profile behavior during FRCP for numerous scenarios. The numerical solution for SFM-FRCP in different scenarios, such as the validation, training, and testing procedures of LMB-SNNs, is carried out. Moreover, the state transition index, fitness outline, mean square error, histogram error, and regression presentation also endorse the strength and reliability of the solver LMB-SNNs for SFM-FRCP. The comparative analyses and performance studies through outputs of regression drawings, absolute error, and error histograms validate the effectiveness of the suggested solver LMB-SNNs. The method's precision is verified by the closest numerical outputs of both built and dataset values with similar levels 10−11–10−14. Furthermore, it has been observed that as the non-Newtonian parameter increases, the fluid velocity decreases. The research work carried out in this paper is original and fills a gap in the existing research by showing the rheological properties of the Sisko fluid model and the implementation of the LMB-SNNs during the FRCP.

A multi-stage enhanced flocculation reactor for the treatment of simulated shale gas hydraulic fracturing flowback fluid: Effect of aspect ratios for the intense mixing section

Flocculation is a significant process in treating shale gas hydraulic fracturing flowback fluids. To achieve a high removal rate of pollutant, a range of multi-stage enhanced flocculation reactors that incorporated sequential intense, moderate, and weak mixing sections along the flow direction were devised, in which the aspect ratios (ARs) in the intense mixing section were varied. The results of the computer simulation indicated that the reactor with AR of 3.5 exhibited a gradual decrease in velocity and energy along the flow direction, and the flow field distribution is highly uniform and symmetrical. The generated flow field promoted the formation of small flocs in the intense mixing section and facilitated the collision of small flocs in the moderate mixing section, while preventing the fragmentation of flocs in the weak mixing section, therefore resulting in the generation of large and compact flocs. Moreover, the generated flocs demonstrated a good resistance to shear and oscillation, facilitating their separation from the simulated flowback fluids. The obtained reactor achieved remarkable removal efficiencies of 80.15 % for COD and 89.06 % for turbidity. Furthermore, when treating bentonite suspension, the multi-stage flocculation reactor achieved a turbidity removal rate of 99.34 % with a processing time of only 2.38 min and a settling time of just 20 min. This demonstrated the broad applicability of this reactor to various types of wastewater. This work provides valuable insights into the design of efficient flocculation reactors by integrating multiple mixing intensities within a reactor.

The Effect of Ipsilateral Carotid Revascularization on Contralateral Carotid Duplex Parameters in Patients with Bilateral Carotid Stenosis

Duplex-derived velocity measurements are often used to determine the need for carotid revascularization. There is evidence that severe ipsilateral carotid stenosis can cause artificially elevated velocities in the contralateral carotid artery, which may decrease following ipsilateral revascularization. The objective of this study was to determine if contralateral carotid artery duplex velocities decrease following ipsilateral carotid endarterectomy or stenting procedures. This is a single institutional retrospective study of prospectively collected data on all patients who underwent carotid revascularization from 2013 to 2021. Patients with immediate preoperative and first postoperative Duplex scan within 4months of carotid revascularization at our vascular laboratory were included for analysis. Patients with contralateral occlusion were excluded. Duplex criteria used to define moderate (50-69%) and severe (>70%) stenosis were systolic velocity ≥125cm/sec and ≥230cm/sec, respectively. Between 2013 and 2021, 129 patients with bilateral carotid stenosis underwent either carotid endarterectomy (98) or a stenting procedure (31). The majority of patients (90%) underwent intervention for severe stenosis. Preoperatively, the contralateral artery was categorized as severe in 30.4% patients. After ipsilateral carotid revascularization, 86 patients (67.2%) saw a decrease in the contralateral artery peak systolic velocity (PSV), while the remaining remained stable or increased. Fifty-four patients had a change in designated stenosis severity in the contralateral artery. Between the carotid endarterectomy and stenting cohorts, there was no significant difference in the proportion of patients whose contralateral velocity decreased (69.4% vs. 61.3%, P=0.402). Patients with coronary artery disease and diabetes were significantly less likely to experience a decrease in the contralateral artery PSV after ipsilateral intervention (P=0.018 and P=0.033). In patients with bilateral carotid disease, ipsilateral revascularization can change the contralateral artery velocity and perceived disease severity. Most patients were noted to have a decrease in the contralateral artery PSV, although almost one-third either stayed stable or increased. On multivariable analysis, patients with coronary artery disease and diabetes were less likely to see a decrease in the contralateral artery PSV after intervention. Patients who are at risk for artificial elevation of the contralateral artery may warrant a re-evaluation of the contralateral artery after ipsilateral intervention. These patients are potentially better assessed with axial imaging, although further research is needed.

Experimental investigation of heating augmentation by particle kinetic energy conversion in dust-laden supersonic flows

The presence of particles in supersonic flows can cause significant increases in stagnation point heat fluxes (Dunbar et al. in AIAA J 13:908–912, 1975). This effect is commonly named ‘particle-induced heat flux augmentation’ or just ‘heating augmentation.’ Heating augmentation can be described as the sum of the conversion of kinetic energy of the particles into thermal energy, characterized by the energy conversion efficiency, also called accommodation coefficient, and the increase of convective heat flux (Polezhaev et al. in High Temp 30:1147–1153, 1992; Vasilevskii and Osiptsov in Experimental and numerical study of heat transfer on a blunt body in dusty hypersonic flow 33rd thermophysics conference, American Institute of Aeronautics and Astronautics, 1999). Although the accommodation coefficient is fundamental for heating augmentation characterization, there is only a small number of experimental datasets for it. This work focusses on the experimental determination of the accommodation coefficient in flow regimes at Mach number 2.1, Reynolds number, based on the probe nose diameter, from approx. 6e5 to 1.8e6, and nominal particle sizes of approx. 20 µm. The decrease of particle velocity and kinetic energy flux in the shock layer is measured with highly resolved shadowgraphy for individual particles. The particle kinetic energy flux is decreased by 29% on average by particle deceleration in the shock layer. Negligible kinetic energy fluxes of rebounded particles were measured. The accommodation coefficient is approx. 0.36 for Al2O3 and SiO2 particles, while it is approx. 0.09 for MgO particles. Hence, it is significantly smaller than the widely used value of 0.7, based on the study of (Fleener and Watson in Convective heating in dust-laden hypersonic flows 8th thermophysics conference, 1973), but in good agreement with values given in (Hove and Shih in Reentry vehicle stagnation region heat transfer in particle environments 15th aerospace sciences meeting, 1977) and (Molleson and Stasenko in High Temp 55:87–94, 2017. https://doi.org/10.1134/S0018151X1701014X ). No difference between erosive and elastic particle reflection mode was detected on the conversion efficiency. The data from a simplification of the modeling approach of the conversion efficiency for elastic particle reflection by Molleson and Stasenko (2017) are in poor agreement with experimental data.

An experimental study on edge-affected frosting characteristics on a vertical cold plate at different air velocities

Frosting always plays negative roles in engineering fields. To accurately predict and control the frosting process on the vertical plate surface with the edge effect considered, an experimental study on the frosting characteristics with air velocities between 1.2 m/s and 2.2 m/s of a vertical cold plate is conducted. The results show that the droplet condensation and coalescence stage duration obviously decreases as the air velocity decreases, while the edge effect has not a significant influence on this duration. Besides, the edge effect and the rise of air velocity will facilitate an increase in the droplet growth. The droplet growth coefficients in edge-affected regions for Cases 1, 2, and 3 are around 1.02, 1.06, and 1.19, and those in unaffected regions are 0.96, 1.01, and 1.07, respectively. At the end of the droplet condensation and coalescence stage, the equivalent width of the edge-affected regions for Cases 1, 2, and 3 are 2.46 × 10−4 m, 1.77 × 10−4 m, and 1.91 × 10−4 m, respectively. The average frost layer thickness reaches 8.97 × 10−4 m for 1.2 m/s at 2,400 s, and it increases by 7.6 % and 12.6 % when the air velocity increases to 1.7 m/s and 2.2 m/s, respectively. The results of this study are expected to deepen the understanding of the frost formation process on a vertical cold plate, and guide the frost detection and defrosting technologies.

Method of dynamic one-stage Dopplerography of coronary and cerebral blood flow with analysis of efficiency of antler balneotherapy in patients with arterial hypertension

Integration of highly sensitive Doppler methods of assessment of coronary and cerebral blood circulation into process of functional and diagnostic audit of results of recovery treatment of patients with an arterial hypertension allows to estimate positive tendencies at normalization of processes regional perfusion. Use of the designated technologies showed reliable decrease in peak velocity in middle cerebra artery without increase in vascular resistance at the persons which passed a therapeutic course of antler reindeer breeding.Peak velocity in an middle cerebra artery before the designated treatment was within 92–115 cm/ c (Me 105 [96,3–104,5]), after the therapeutic procedures was registered in a big way 78–98 cm / c (Me 90 [82,4–94,3]). The designated phenomenon indicated improvement of regional cerebral oxygenation and natural reduction of volume of brain perfusion. At the same time, Doppler parameters in coronary arteries at the patients who completed the analyzed course of recovery treatment were transformed minimum, without reliable distinctions that presumably.

Cool season near-surface wind speed trends across the central Appalachian Mountains region of the eastern United States, 1995-2022

ABSTRACT Prompted by recent findings of a common trend toward lesser near-surface winds (NSW), or stilling, time series of cool season NSW variables for 20 stations in the central Appalachian Mountains of the eastern United States were examined for trends during the period 1995–2022. While not universal across the station array, results generally indicate an increase in the frequency of calm conditions, a decrease in mean wind velocity, and a decrease in the frequency of high-wind days. Contrasting this was a general increase in high-wind gust days. The evidence for stilling was supported by an increase in the frequency of days with a 12-hour pressure change of zero and an apparent strengthening and northwestward expansion of the subtropical ridge over the region. Supporting the increase in high-wind gust days was an increase in the frequency of days with a large 3-hour pressure change, and lesser geopotential heights in the lower atmosphere northwest of the region, which contrasts the expanding subtropical ridge and together presents the potential for periodic placement of stronger dynamics across the region.

Effect of Groundwater Level Rise on the Critical Velocity of High-Speed Railway

The increasing frequency of extreme rainfall is leading to a rise in groundwater levels in coastal areas, significantly affecting high-speed railway operations. To address this concern, this study developed a 2.5-dimensional finite element model of a coupled track-embankment-ground system based on Biot’s porous media theory to analyze the effect of groundwater level rise on the critical velocity of high-speed railways and vibration responses. The findings reveal a consistent decrease in the critical velocity of high-speed railways with rising groundwater levels. Particularly, the increase in groundwater levels within the embankment significantly influences the critical velocity compared to a similar rise in the foundation’s groundwater level. Furthermore, deformations induced by passing trains significantly increase as groundwater levels rise. Specifically, when the groundwater level rises from the foundation bottom to the subgrade surface, subgrade surface deformation increases by approximately 55%. As trains approach the critical velocity, significant vibration phenomena, known as the “Mach effect,” occur at the foundation surface. Importantly, as groundwater levels rise, the “Mach effect” intensifies. Analyzing the vibrating frequency spectrum of the displacement response demonstrates a substantial increase in vibration amplitude, particularly in the high-frequency region, as groundwater levels rise. This study highlights that the rise in groundwater level not only amplifies vibrations but also extends the propagation of high-frequency vibrations, underscoring the importance of effective embankment waterproofing in controlling track vibrations.

Glacier slowdown and rapid ice loss in the Tinguiririca and Cachapoal Basin, Central Andes of Chile

The central region of Chile is home to nearly 10 million people, 60% of the country's population. This area's water supply is reliant on glacial meltwater from the Andes, especially during the dry summer months. However, the current ice volumes and rates of ice loss remain uncertain in many glacierized Andean basins. Our study investigated the dynamics of glaciers located in the high-altitude Tinguiririca and Cachapoal Basin over the period 2016–2022, by measuring their surface velocity and inverting for changes in ice thickness. We measured the glacier surface velocities using the Glacier Image Velocimetry toolbox on Sentinel 2 images, merging over 6000 individual velocity measurements into median annual velocity maps. We then used ice velocities as input for ice-thickness inversions to calculate ice-thickness maps and ice volumes using an ensemble of four different methods. We detect a decrease in surface velocity from 2016 to 2022 on the Universidad, Cortaderal, Norte Cipreses glaciers and southern part of the Palomo glacier, while the Cipreses glacier and the northern part of the Palomo glacier showed a decrease in velocity between 2016 and 2021 and then an acceleration in 2022. Ice thickness data shows an ice volume loss of between 0.34 ± 0.22 and 0.43 ± 0.18 km3/yr depending on the method used, equivalent to ∼25% of the total ice volume lost from 2016 to 2022. The current rates of ice volume loss are unsustainable beyond the next two decades, reducing or entirely removing the glacial contribution to streamflow and increasing pressure on local water resources.

Quantification of mixed hydrate and free gas concentrations by the joint integration of velocity and conductivity information

Quantification of gas hydrates in marine sediments is crucial for understanding gas hydrate systems. By empirical relationships or effective medium modelling, gas hydrate concentrations can be derived from velocity and/or conductivity logs. However, these approaches do not take the co-occurrence of free gas and gas hydrate into account leading to large uncertainties in the calculated free gas and gas hydrate concentrations. To overcome this issue we adopt a joint elastic and electric self-consistent/differential effective medium model as the basis for a new joint inversion scheme that distinguishes between both phases. We apply this scheme to p-wave velocity and electric induction data measured by downhole-logging of boreholes at Formosa Ridge off Taiwan - a known hydrate province with an active gas conduit. Gaussian Mixture Modeling separates the background signal of the host medium from anomalies and allows to determine a background porosity as a probability density function of depth. We use this derived porosity to jointly invert electrical conductivity and velocity data for hydrate and free gas concentrations. At Formosa Ridge, we find two resistive anomalies, one in the shallow and another in the deep part of the borehole. Only the deep anomaly in conductivity coincides with a high-velocity anomaly. This is consistent with ∼30% hydrate with ∼1% free gas concentration. For the shallow anomaly, increased velocities due to hydrate concentrations of ∼15% are compensated by a decrease in velocity due to ∼1% of free gas. The method reconciles the different sensitivities of the two data types and yields hydrate and free gas concentrations that are largely consistent with geochemically derived values.

Research on Pipeline Leakage Calculation and Correction Method Based on Numerical Calculation Method

The hazard coefficient for leakage diffusion of gas transmission pipeline is extremely high, which can easily lead to explosive accidents. The amount of gas leakage is an important factor in the safety assessment of pipeline leakage. Therefore, this paper considers the influence of gas interactions inside and outside the pipeline on pipeline leakage and establishes a three-dimensional leakage diffusion model that is coupled with the pipeline and air domain. Through the use of theoretical, experimental, and numerical simulation methods, this paper investigates the effects of leak hole diameter, leak hole shape, and changes in transport pressure on pipeline leakage. Finally, based on simulated leakage data, we analyze the sources of error and propose a high-precision formula for calculating leakage from small holes in pipelines. The results show that an increase in the diameter of the leak hole leads to a decrease in the central velocity of the leak hole and a sharp increase in leakage volume. The leakage volume of different leak hole shapes is ranked in the following order: rectangle > diamond > circle. When the leak holes are rectangle and diamond, the leakage velocity distribution range of the leak hole is larger and more regular than that of the circular leak hole. Also, the volume of gas leakage increases with the increase in delivery pressure, while the central velocity of the leak hole remains relatively unchanged. Based on the proposed pipeline leakage correction formula, it is calculated that under the same working condition, the relative error range between the numerical simulated leakage rate and the theoretically corrected leakage rate is significantly reduced from −8.40%~18.03% to −1.58%~2.60%, and the calculation accuracy is significantly improved.

The Effect of Cation Incorporation on the Elastic and Vibrational Properties of Mixed Lead Chloride Perovskite Single Crystals

In recent years, there have been intense studies on hybrid organic–inorganic compounds (HOIPs) due to their tunable and adaptable features. This present study reports the vibrational, structural, and elastic properties of mixed halide single crystals of MAxFA1-xPbCl3 at room temperature by introducing the FA cation at the A-site of the perovskite crystal structure. Powder X-ray diffraction analysis confirmed that its cubic crystal symmetry is similar to that of MAPbCl3 and FAPbCl3 with no secondary phases, indicating a successful synthesis of the MAxFA1-xPbCl3 mixed halide single crystals. Structural analysis confirmed that the FA substitution increases the lattice constant with increasing FA concentration. Raman spectroscopy provided insight into the vibrational modes, revealing the successful incorporation of the FA cation into the system. Brillouin spectroscopy was used to investigate the changes in the elastic properties induced via the FA substitution. A monotonic decrease in the sound velocity and the elastic constant suggests that the incorporation of large FA cations causes distortion within the inorganic framework, altering bond lengths and angles and ultimately resulting in decreased elastic constants. An analysis of the absorption coefficient revealed lower attenuation coefficients as the FA content increased, indicating reduced damping effects and internal friction. The current findings can facilitate the fundamental understanding of mixed lead chloride perovskite materials and pave the way for future investigations to exploit the unique properties of mixed halide perovskites for advanced optoelectronic applications.

Entropy generation analysis of non-miscible couple stress and Newtonian fluid in an inclined porous channel with variable flow properties: HAM Analysis

The aim of this study is to investigate the entropy production characteristics of two non-miscible fluids in an inclined porous channel with temperature-dependent thermal conductivity and viscosity. The porous region of the channel is divided in two regions. In region-1 and region-2, the Couple stress and Newtonian fluid take place due to constant pressure gradient, respectively, under the influence of a uniform magnetic field. Here, the Darcy–Brinkman model is used for the flow of immiscible fluid through the porous media. In this work, we used a semi-analytical method named as homotopy analysis method (HAM) to solve the coupled nonlinear ordinary differential equations. The goal of the considered problem is to examine the consequences of a variety of thermophysical parameters, including Hartmann number, varying viscosity parameter, varying thermal conductivity parameters, and Grashof number on the characteristics of entropy generation, Bejan number distribution, thermal behavior and flow characteristics of non-miscible couple stress and Newtonian fluid passing through a porous channel. The novel aspect of this study is the formation of entropy and Bejan number as a result of non-miscible Newtonian and couple stress fluids with varying thermal conductivity and viscosity in porous media. In terms of rheological investigation, a semi-analytical simulation for changeable thermal and flow properties in an immiscible Newtonian and couple stress fluid via an inclined porous channel is a brand-new concept, and the behaviors of such flows have not been examined yet. From this study, it is concluded that on raising the variable thermal conductivity, Hartmann number and the permeability of the porous medium, the flow velocity, thermal characteristics and entropy generation number decrease. The authors also come to the significant conclusion that non-miscible Newtonian and couple stress fluids have larger entropy production numbers, flow velocities, and temperature profiles for higher values of Grashof number, variable viscosity parameter, and couple stress parameter. The findings of this work have also been graphically validated through the previously established work. The results of the present analysis can be used in petroleum industry, lubrication theory, etc.

Effects of polymer and dust particles inclusion on drag and heat transfer characteristics in Non-Newtonian dusty fluids

The objective of this article is to examine the simultaneous incorporation of polymers and dust particles, a previously unexplored topic according to the available literature. Understanding these effects is essential for industrial processes and biomedical engineering applications where the manipulation of drag and heat transfer characteristics is desired. This research looks at how including polymers in a viscous non-Newtonian FENE-P dusty fluid alters the flow and heat transfer characteristics of the boundary layer over a non-linearly stretched surface. By employing an appropriate similarity transformation method, we transform the nonlinear system of equations into an equivalent form that exhibits similarity. The resulting boundary layer equations are then numerically solved to investigate the effect of flow factors on the drag force and Nusselt number. This analysis allows us to investigate how various flow parameters influence the forces experienced by the fluid and the rate of heat transfer. In our investigations, we observe a decrease in velocity and an increase in heat transfer when both polymers and dust particles are present. These results suggest that the presence of polymers and dust particles simultaneously has a positive effect on fluid dynamics and increases the system’s thermal exchange efficacy.