Background: Within the realm of mental distress experienced by women who are unable to conceive, tension, uncertainty, and anxiety are prevalent concerns. The multitude of unpredictable elements that occur during IVF treatment process can cause anxiety and stress. This unpleasant feeling has an impact on the psycho-neurological pathways of women who are unable to conceive. As a consequence, fertilisation and implantation are inhibited, leading to adverse effects on pregnancy. The individual's experience will vary depending on the extent of social support, the coping mechanisms employed, the quality of the marital connection, and the level of stress caused by infertility. Material and method: The study was carried out on 20 women undergoing IVF treatment. Participants were selected by simple random sampling technique. (COMPI) Fertility Problem Stress Scale, Uncertainty Scale for Infertile Women and Short Version of the Spielberger State—trait Anxiety Inventory were used to assess the level of stress, uncertainty and anxiety. Results: The findings of the current study indicate that 80% of women undergoing IVF in the experimental group experienced a moderate degree of stress prior to the intervention. However, this percentage decreased to 60% after receiving intervention. In case of uncertainty maximum of women had mild level of uncertainty and it remain unchanged in experimental group after intervention However, there was a significant decrease in anxiety levels (both STAIS and STAIT) in the experimental group following the intervention. Participants that received psychotherapeutic nursing intervention showed a higher rate of implantation. Conclusion: Psychotherapeutic nursing intervention can decrease the anxiety among women undergoing in vitro fertilisation treatment and also enhance the implantation rate.
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