Given English orthography's quasi-regular nature, applying common decoding rules to a word does not always result in a correct pronunciation matching the stored phonological form (e.g., the word tongue). To arrive at a correct pronunciation, developing readers must make the match between a decoded pronunciation and a word's correct pronunciation stored in memory. Developmentally, this matching process varies as a function of child skill (e.g., decoding, vocabulary) and word characteristics (e.g., spelling-to-pronunciation transparency, concreteness), with each being continuously distributed. Spelling-to-pronunciation transparency ratings represent a global measure of the ease of arriving at a word's correct pronunciation from its decoded pronunciation and in experimental studies has been shown to be a critical dimension in assessing the difficulty of a word for developing readers (e.g., Steacy et al., 2022a, 2022b). This study aimed to create a database of spelling-to-pronunciation transparency ratings for the 23,282 most frequently written English words, made available in the supplemental materials for future analyses. We asked adults to rate words' spelling-to-pronunciation transparency on a scale of 1-6 (1 = very easy to match, 6 = very difficult). Results of multiple regression analyses revealed variance in ratings to be unaccounted for by other word features, demonstrating the uniqueness of these ratings. Furthermore, words that are considered irregular, classified previously as strange, or contained at least one schwa received higher ratings, demonstrating strong associations between transparency and regularity. Lastly, these ratings significantly predicted both adult word naming time and child word reading accuracy above and beyond other word features known to predict reading.