Potentially Soil Mineralizable Nitrogen (PMN) is critical in soil health and crop production. This review paper explores the impact of PMN on soil health, crop production, different soil types, and mitigation strategies. It highlights the importance of PMN in enhancing nutrient availability, crop yield, and quality. The paper discusses the role of PMN in promoting soil organic matter accumulation, supporting microbial activity, and improving soil physical properties. Case studies illustrate the influence of PMN on different soil types and associated crops. Mitigation and management strategies are discussed, such as soil organic matter management, precision nutrient management, and crop rotation/diversification. The review also identifies future research directions, including refining PMN measurement techniques, integrating into nutrient management decision support systems, and exploring PMN interactions with other soil properties and environmental factors. Overall, effective PMN management is crucial for sustainable agriculture, and further research and collaboration are needed to advance our understanding and develop practical strategies for its implementation.