High school education is the doorstep towards the future of students, whether they will pursue further education or enter the world of work. The study aimed to determine the factors affecting the career choice decisions of selected junior high school students in Calamba City, Philippines. Using case study as a research design, the study utilized a survey questionnaire to gather responses of 234 junior high school students where data gathered were analyzed using descriptive analysis. Results of the study showed that economic factors, such as financial stability and returns received strong agreement from students, while social factors got the most disagreement. Meanwhile, more than half of the respondents are inclined towards STEM-related degree programs and majority of them eye state university and colleges (SUCs) as prospective schools after graduation. The findings became the basis of the proposed localized career guidance program to further guide these students. Recommendations include revisiting existing policies on career guidance and empowerment of SUCs.