Due to the unique geographical and geological conditions in the Sino-Nepal transportation corridor, there is a lack of reliable and comprehensive data on debris flow distribution data in the region. This dataset is compiled based on early identification of debris flows and field surveys, integrating Digital Elevation Models (DEM) and geological maps. It provides a catalog and detailed feature information of debris flows within the corridor along the National Highway 318 between China and Nepal from 1990 to 2022. Precipitation and temperature parameters are derived from 30 years (1980–2009) of interpolated data from national meteorological stations. Fault distribution information is sourced from the 1:50,000 digital geological maps published by the China Geological Survey. Terrain information is obtained from NASA's Shuttle Radar Topography Mission (SRTM) data, which provides a global DEM at a resolution of 12.5 m. Within the geographical coordinates of 28.0°–29.4°N and 85.1°–88.9°E, a total of 255 debris flow records have been extracted, covering an area of 1660.73 km². We primarily employed hydrological analysis methods in ArcGIS for the extraction of debris flow basins. Considering the limitations in DEM accuracy, we made necessary manual corrections with reference to Google Earth imagery. The dataset comprises three files: a vector file depicting the main distribution range of debris flows along the National Highway 318 in the Sino-Nepalese transport corridor; a vector file containing the catalog of debris flows; and a document detailing the parameters and characteristics of the debris flows.The dataset has undergone on-site field surveys and confirmation to ensure its reliability. Therefore, it can serve as a foundational dataset applicable to debris flow studies in the region.