Ambivalence, according to historian and political science professor Abbas Milani, is the fundamental principle upon which democracy is built.1 Admitting to not knowing the “truth” and a willingness to search for answers with others is the pledge that every believer of democracy should make. In Professor Milani’s view, totalitarian regimes, whether religious, military, or monarchist, can never coexist with democracy. These regimes generally claim to know the truth already, hence violating this foremost tenet of democracy.1 In an ideal democratic society, the people, or their representatives, agree that they do not know the truth, but they arrive at conclusions and act on those conclusions based on their best efforts at fact-finding.2 While searching for the truth and keeping an open mind amid new findings, the people are expected to remain critical of their administration and its decisions and keep the governing body in check. Demosthenes, a Greek philosopher, noted, “There is one safeguard known generally to the wise, which is an advantage and security to all, especially to democracies as against despots. What is it? Distrust.” Evidence-based medicine (EBM) in many ways follows these principles of democracy. By pursuing EBM, one admits to not knowing the definitive truth, expresses a willingness to hear different arguments and suggested solutions, and promises to be constructively critical of every proposal. Believers of EBM, just like supporters of democracy, carry an important responsibility on their shoulders. Selecting accurate and reliable information from a constantly growing pool of data demands exceptional skills: discerning high-quality studies, critically appraising them, and putting them to use in clinical practice.3 This strategy, combined with one’s clinical judgment and consideration of the patient’s values, preferences, and circumstances, guarantees a more accurate and satisfying decision-making process and a more favorable outcome for both the patient and the physician.4,5 It also promises the delivery of better and more updated care and management, fulfilling the principal mission of EBM: to improve patient care.6 In line with the mission of Academic Emergency Medicine (AEM) to promote EBM, a new series, the “Structured Evidence-Based Medicine Reviews,” is introduced in this issue. These reviews will be published under the “Progressive Clinical Practice” section. AEM is proud to provide another venue for showcasing up-to-date and high-quality extracts of evidence to its audience. The editors believe that producing and publishing such reviews through this channel will improve the transfer of evidence from research to the bedside, policies, and guidelines, thereby facilitating the closure of the existing knowledge translation gap.7 In the first of this series, the issue of early and aggressive treatment of postinjury coagulopathy—by way of transfusing packed red blood cell (PRBC) and fresh frozen plasma (FFP) in a 1:1 ratio to emergency department patients with severe trauma—is analyzed.8 In this structured EBM review, a carefully formatted research question is presented first, and the target population, type of interventions, comparisons, and desired study designs are then determined. These elements are specified to examine their impact on a clinically relevant and patient-oriented outcome: mortality. Next, a thorough search of the major medical databases is performed to identify the studies that match the predetermined inclusion and exclusion criteria, set by the authors. In the fourth step, the previously published standard criteria are used to assess the quality of the selected articles. Finally, the results of the selected studies are summarized and the application of the existing evidence to clinical practice is discussed. These structured EBM reviews are not intended to replace rigorous systematic reviews. Rather, they are designed to provide and analyze the existing evidence related to patient-oriented research questions when high-quality systematic reviews are not available.9 Since the emergence of new studies over time may sway the evidence to one side or another, the authors of these structured reviews will be asked to update their reviews every 2 or 3 years, especially when new studies on the topic surface. Academic Emergency Medicine hopes that authors will welcome this opportunity, and by preparing similar structured reviews, help eliminate the myths and anecdotes that are still incorporated in our clinical practice. We encourage authors to contact the journal ([email protected]) if they are interested in writing a structured EBM review or if they have a research question that might be suitable for such a review. A detailed set of instructions on how to write these reviews is presented in the “Instructions for Authors” on the AEM website (http://www.wiley.com/bw/submit.asp?ref=1069-6563&site=1). The duty of AEM is to seek and disseminate strategies that bring EBM, and hence better care, to the patient’s bedside. Applying EBM to day-to-day practice, just like democracy, requires constant scrutiny, vigilance, and inquiry. The contemporary educator and philosopher, Robert M. Hutchins, rightfully said, “The death of democracy is not likely to be an assassination from ambush. It will be a slow extinction from apathy, indifference, and undernourishment.”10