De Canarias Research Articles

Near-infrared Spectral Homogeneity of the Didymos System Before and After the DART Impact* * Based on observations made with the Italian Telescopio Nazionale Galileo (TNG) operated on the island of La Palma by the Fundación Galileo Galilei of the Istituto Nazionale di Astrofisica (INAF) at the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofisica de Canarias

We spectroscopically characterized the Didymos system, target of the Double Asteroid Redirection Test (DART)/Light Italian Cubesat for Imaging of Asteroids (LICIACube) space mission, close in time to the DART impact event, during six nights between 2022 August and November at Telescopio Nazionale Galileo. Here, we show that near-infrared (NIR) spectra (0.75–2.25 μm) look mostly similar within the same night and between different nights. They are in good agreement with the only spectrum previously available in the literature, observed almost 20 years before those reported in this paper. During one of the observing nights we also obtain spectroscopy information on the ejecta tail induced by the DART impact. The spectrum of the ejecta tail is also very similar to Didymos/Dimorphos itself. All of these aspects seem to suggest that the Didymos system in the NIR looks mostly homogeneous, with very subtle spectral variations.

Background levels and brain organoid impact of RF field exposure in a healthcare environment

Introduction: This study is an introduction to the empirical and impact evaluation of radiofrequency electromagnetic field (RF-EMF) radiation exposure in a healthcare environment, focusing on an indoor microenvironment. It explores the expression of various genes associated with cellular responses, cell proliferation, senescence, and apoptotic cell death. The assessment analyzes current personal mobile communications (2G-5G FR1), providing a clear understanding of RF-EMF exposure and compliance with regulatory limits.Methods: The signals from different wireless communication systems at Hospital Universitario de Canarias (HUC) in Tenerife, Canary Islands, Spain, were examined in 11 locations. Four measurement campaigns were performed with frequency-selective exposimeters (PEMs) and an EME Spy 200 MVG, and experimental electric field values were compared as a long-term exposition. The frequency with the highest contribution (2.174 V/m) observed (1840 MHz) in UMTS was selected for biological effects evaluation.Results: The study focuses on four locations with the highest exposure to communication systems (downlinks), analyzing the results to verify compliance with regulations that ensure the safety of patients, the general public, and healthcare workers. LTE B20 (DL), GSM+UMTS 900 (DL), GSM 1800 (DL), UMTS 2100 (DL), and LTE B7 (DL) exhibited relatively higher E/m values throughout the campaigns, and these values consistently remained below the ICNIRP reference levels, signifying a consistently low level of exposure. In addition, this work presents the biological effects on neural stem cells (NSCs) using 3D brain organoids (BOs) exposed to RF signals in a validated and commercial experimental setting: the Gigahertz Transverse Electromagnetic cell (GTEM). The GTEM allows for the creation of homogeneous field electromagnetic fields in a small, enclosed setting and guarantees exposure conditions in a wide range of frequencies. BOs are an in vitro 3D cell-culture technology that reproduces the cellular composition and structure of the developing brain. Analyzing the expression of several genes associated with cellular responses, cell proliferation, senescence, and apoptotic cell death, we found that exposure of BOs at 1840 MHz did not affect mRNA expression in brain genes related to apoptosis or senescence. However, a decrease in gene expression for cell proliferation and cell activity markers was observed during the differentiation stage of BOs.Discussion: The discussion emphasizes the coexistence and evolution of various heterogeneous networks and services throughout the four measurement campaigns. Across all measured results, the levels of the obtained E-field were consistently well below the exposure limits set by internationally accepted standards and guidelines. These obtained values have been established in order to consider their potential effects on cell proliferation and cell activity, especially in differentiating biological organisms. Consequently, the results obtained and the methodology presented could serve as a foundational framework for establishing the basis of RF-EMF assessment in future heterogeneous 5G developments, particularly in the millimeter wave (mmWave) frequency range, where the forecast is for massive high-node density networks.

The ASTRI Mini-Array: A New Pathfinder for Imaging Cherenkov Telescope Arrays

The ASTRI Mini-Array is an Istituto Nazionale di Astrofisica (INAF) project to build and operate an array of nine Imaging Atmospheric Cherenkov Telescopes (IACTs) at the Teide Astronomical Observatory of the Instituto de Astrofisica de Canarias in Tenerife (Spain) based on a host agreement with INAF and, as such, it will be the largest IACT array until the Cherenkov Telescope Array Observatory starts operations. Implementing the ASTRI Mini-Array poses several challenges from technical, logistic, and management points of view. Starting from the description of the innovative technologies adopted to build the telescopes, we will discuss the solutions adopted to overcome these challenges, making the ASTRI Mini-Array a great instrument to perform deep observations of the galactic and extra-galactic sky at very high energies.

Evaluation of the thermo-elastic response of space telescopes using uncertainty assessment

The aerospace sector is evolving due to reduced launch costs and standardization of small satellite platforms. This research, aligned with European Guidelines for Thermo-Elastic Verification, addresses the pointing precision gap in small satellites by assessing space telescope performance using uncertainty propagation in thermo-elastic models. The methodology will be directly applied to an Earth observation space telescope, VINIS, currently under development by the Instituto de Astrofísica de Canarias (IAC). This procedure helps to identify key design elements impacting its functionality. Thirteen elements were identified as main contributors to the deformations in the optical bench. Due to the bench's crucial role in the telescope's performance, this paper also explores how results vary with different sandwich panel modelling techniques and the enhancements from design modifications. While the focus is on space telescopes, this approach has broader applicability to thermo-elastic analysis of various space instruments.

Optimizing Space Telescopes’ Thermal Performance through Uncertainty Analysis: Identification of Critical Parameters and Shaping Test Strategy Development

The integration of uncertainty analysis methodologies allows for improving design efficiency, particularly in the context of instruments that demand precise pointing accuracy, such as space telescopes. Focusing on the VINIS Earth observation telescope developed by the Instituto de Astrofísica de Canarias (IAC), this paper reports an uncertainty analysis on a thermal model aimed at improving cost savings in the future testing phases. The primary objective was to identify critical parameters impacting thermal performance and reduce overdesign. Employing the Statistical Error Analysis (SEA) method across several operational scenarios, the research identifies key factors, including the Earth’s infrared temperature and albedo, and the spacecraft’s attitude and environmental conditions, as the variables with major influences on the system’s thermal performance. Ultimately, the findings suggest that uncertainty-based analysis is a potent tool for guiding thermal control system design in space platforms, promoting efficiency and reliability. This methodology not only provides a framework for optimizing thermal design and testing in space missions but also ensures that instruments like the VINIS telescope maintain optimal operating temperatures in diverse space environments, thereby increasing mission robustness and enabling precise resource allocation.

The ASTRI Mini-Array

The ASTRI Mini-Array is an INAF project to build and operate a facility to study astronomical sources emitting very high energy in the TeV spectral band. It consists of a group of nine innovative aplanatic dual mirror Imaging Atmospheric Cherenkov Telescopes (IACT) of 4 m diameter. The telescopes are being installed at the Teide Astronomical Observatory of the Instituto de Astrofisica de Canarias in Tenerife (Canary Islands, Spain) based on a host agreement with INAF. Thanks to its expected overall performance, better than those of current IACT arrays, for energies above about 5 TeV and up to 100 TeV and beyond, the ASTRI Mini-Array will represent an important instrument to perform deep observations of the Galactic and extra-Galactic sky at these energies with high angular resolution (a few arcmins). It will be complementary to the wide-field particle shower arrays (based on water Cherenkov and scintillator detectors) like HAWC and LHAASO already operated in the northern hemisphere. The ASTRI Mini-Array is currently under construction and in this paper, we will present its status, discussing its design and expected performance.

Incidence of non-canonical IDH mutations and IDH co-mutations in a multicenter prospective study of patients with glioma.

e14033 Background: IDH-mutant tumors are a distinct disease entity accounting for one third of gliomas with a more favourable prognosis despite still harboring high morbidity and mortality rates. Most IDH mutations (muts) in gliomas group at R132/R172 hotspots in IDH1/IDH2, respectively. Our aim was to study IDH non-canonical muts and IDH co-mutations (co-muts) since the evidence is still limited. Methods: Prospective study of patients (pts) with gliomas at 4 third-level hospitals in Spain (Hospital Clinico Universitario San Carlos, Hospital Universitario La Paz, Hospital Universitario de Canarias, Hospital Universitario Nuestra Señora de la Candelaria). High throughput next generation sequencing (NGS) using a customized gene panel ((Illumina, Inc) including IDH1 and IDH2 was used in FFPE and/or fresh tumor samples, and run in an Illumina MiSeq instrument (Illumina, Inc). Only pathogenic mutations were considered as valid. Clonal IDH (cIDH) muts were defined as those with a MAF ≥ 1% and subclonal IDH (scIDH) muts as those with a MAF < 1%. Results: Between February 2017 and February 2021, 49 glioma pts enrolled and sequenced for IDH1/IDH2 tumor muts. Median age 51 (Min-max: 20-78). WHO 5th Ed (n = 42): IDH-MUT astrocytoma (n = 14), IDH-MUT oligodendroglioma (n = 7), IDH-WT glioblastoma (n = 21). 37/49 pts (75.5%) presented cIDH and/or scIDH muts, of which 21 pts (43%) harbored cIDH muts in IDH1 (R132H (n = 17), R132C (n = 1), R132G (n = 1), R100Q (n = 1), G161R (n = 1)) and in IDH2 (R140W (n = 1), R140Q (n = 1)). In 17/21 pts (81%) cIDH-mut MAF ≥ 10%. Of 21 cIDH-mutant pts, there were IDH co-muts in 11 pts (52%). Of these 11 pts, IDH co-muts were scIDH in 91%: #2 (IDH1 R100Q/G161R), #3 (IDH1 R132H/R119Q/G161R), #4 (IDH1 R132H/R132C; IDH2 R172G/R140Q), #11 (IDH1 R132H/R132C), #21 (IDH1 R132H/G161R; IDH2 R140Q), #23 (IDH1 R132H/R132C), #31 (IDH1 R132H/G161R; IDH2 R140Q/P162L), #32 (IDH1 R132H/R100Q), #33 (IDH1 R132H/R100Afs*29/I130V), #37 (IDH1 R132H; IDH2 R159H), #40 (IDH1 R132H; IDH2 R172G). Median overall survival (OS) longer in cIDH-mut vs IDH-wt (159 vs 16 months, P = 0.000). No difference in OS in: cIDH vs cIDH + scIDH (NR vs 67 m, P = 0.437), in scIDH vs cIDH (79 vs 159 m, P = 0.111), and scIDH vs IDH-wt (79 vs 12 m, P = 0.229). Conclusions: Subclonal (defined as MAF < 1%) canonical and non-canonical IDH-mutations and co-mutations occur frequently in gliomas. This may have implications for the design of future clinical trials and in the development of IDH inhibitors including the anticipation of potential resistance mechanisms.

Measured vs estimated renal function on cardiovascular outcomes in an acute heart failure population

Abstract Funding Acknowledgements Type of funding sources: Public hospital(s). Main funding source(s): Complejo Hospitalario Universitario de Canarias, Tenerife -Spain. Background/Introduction HF syndrome is a highly prevalent disease which courses with frequent readmissions, mainly by Acute Heart Failure (AHF). Worsening renal function is associated with increased mortality in patients with HF. Therefore, an accurate and precise evaluation of renal function in patients with HF is crucial. The error of estimated GFR (eGFR) is wide and common, showing ±30% of variability compared to measured GFR (mGFR). However, there is no evidence on the error of the available formulas in reflecting real renal function and particularly the consequences of this error in patients with AHF. Methods This is a prospective pilot study comparing measured versus estimated renal function and its relationship with long-term cardiovascular (CV) outcomes in patients with AHF. A group of patients with AHF who required admission in the CICU were included. Plasma clearance of iohexol, a gold-standard method to mGFR was assessed at the same time as eGFR by five different creatinine- and cystatin c–based equations. The association between estimated or measured GFR and major CV outcomes was evaluated with univariate and multivariate logistic analysis and cox-survival analysis. The main outcome was the first onset of fatal and nonfatal major cardiovascular events during follow-up. Results A total of 90 patients were included. Average age was 66 (± 12 years) and 52 (57,8%) were male. A total of 53 patients (59%) had a cardiovascular event during follow-up, being fatal in 22 cases (41,5%). Other variables are shown in Table 1. None of eGFR was significantly associated with the primary outcome in the unadjusted analyses. In the adjusted regression models, mGFR was significantly associated (p 0,037) with major cardiovascular events when it was correlated with NTproBNP, BMI, LVEF and previous coronary artery disease. mGFR on admission predicts future CV events compared with eGFR based on creatinine or cystatin equations. eGFR overestimates renal function showing around ±20% variability of mGFR in our AHF population (Figure 1). Conclusions Frequently used eGFR formulas in our daily practice in AHF patients do not predict well long-term cardiovascular outcomes. Measured GFR in AHF admission predicts CV events, while eGFR reflects an important variability of the real renal function. Specific subpopulations of AHF may require better evaluation of renal function because it may have prognosis consequences.

(Re)discovering Vicki Penfold's linocuts

Vicki Penfold (Krakow 1918 - Tenerife 2013) was a Polish-born artist who arrived in the Canary Islands in the 1960s after a long pilgrimage to places as disparate as Kenya, Paris and Israel, among others. She also traveled to Austria to become a student of Oskar Kokoschka in his Salzburg studio. Her personal archive, recently donated to the Instituto de Estudios Hispánicos de Canarias (hereafter IEHC) on the island of Tenerife, preserves a wide variety of materials that are currently being inventoried and catalogued. This collection presents a huge potential for study and cross-sectional analysis to address the methodology of the artist and the materiality of his work. This article proposes an initial analysis of the various matrices, relating them to the pieces currently preserved and establishing relationships with the documentation contained in his personal archive. It also aims to highlight Vicki Penfold as a graphic artist, perhaps her most overlooked facet, but one that highlights her enormous sensitivity and versatility in working with a wide variety of techniques.

Safety evaluation of the food enzyme phytepsin from Cynara cardunculus L.

The food enzyme phytepsin (EC3.4.23.40) is extracted from the pistils of the cardoon (Cynara cardunculus L.) by different manufacturers represented by the Dirección General de Salud Pública, Gobierno de Canarias, España. It is intended to be used in milk processing for cheese production. As no concerns arose from the source of the food enzyme, from its manufacture, and based on a history of safe use and consumption, the Panel considered that toxicological data and the estimation of dietary exposure were not required. A search for the similarity of the amino acid sequences of the food enzyme to known allergens was made and no matches were found. The Panel considered that allergic reactions to this phytepsin cannot be excluded in individuals allergic to cardoon. However, the likelihood of allergic reactions to the phytepsin from C. cardunculus L. is expected not to exceed the likelihood of allergic reactions to cardoon. As the prevalence of allergic reactions to cardoon is low, also the likelihood of such reactions to occur to the food enzyme is low. Based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.

Efficacy of a postharvest treatment aiming at eradication of all developmental stages of Tecia solanivora in ware potatoes.

The European Commission requested the EFSA Panelon Plant Health to prepare and deliver a scientific opinion on the efficacy of a postharvest treatment aiming to eradicate all developmental stages of Guatemalan potato tuber moth Tecia solanivora (Lepidoptera: Gelechiidae) in ware potatoes. The Panelevaluated the scientific publication describing the elevated CO2 treatment, which was defined as: 10-day exposure to 30% CO2, 20% O2 and 50% N2 in controlled atmosphere at 17°C on the variety Negra Yema de Huevo (Papas Antiguas de Canarias, PDO potatoes, Solanum chaucha). In the scientific publication, the treatment was applied under semi-commercial and commercial conditions on artificially and field-infested tubers. The effect of the pest developmental stage on the treatment efficacy was investigated with artificial infestation of potato tubers with eggs, neonate and second instar larvae. Pupae and adults were placed in separate containers during the treatment. However, the third and fourth larval instars were not investigated. Further limitations were the sample size in the experiments, the mortality rate in the control group and the unknown level of infestation of the naturally infested potato tubers. It was not possible to evaluate the degree of pest freedom due to incomplete data on the conditions of production, i.e. the infestation level in the field. The Panelwas able to conclude that although no surviving insects were observed in the performed experiments, the statistical evaluation of the presented results from the commercial trial indicate that it cannot be excluded that insects would survive the treatment. For example, based on the data provided the 95% confidence interval of the survival rate for eggs was: 0%-0.453%.

Cliocanarias 5

Cliocanarias is a digital history journal created in 2019, with ISSN 2695-4494 and DOI: 10.53335/Cliocanarias. It is published annually (September), and five issues have been published (the next issue, number 6, will be published in September 2024). Based in San Cristóbal de La Laguna (Canary Islands, Spain), it is independent and its contents are varied, general and refer to a wide territorial projection (Canary Islands, Europe, Latin America), submitting the articles received to a system of anonymous external arbitration. It is listed in the Latindex directory, in the Dialnet and Memoria Digital de Canarias (Jable) portals, and in the institutional repository of the University of La Laguna.

Multiwavelength study of the luminous GRB 210619B observed with Fermi and ASIM

ABSTRACT We report on detailed multiwavelength observations and analysis of the very bright and long GRB 210619B, detected by the Atmosphere-Space Interactions Monitor installed on the International Space Station and the Gamma-ray Burst Monitor (GBM) on-board the Fermi mission. Our main goal is to understand the radiation mechanisms and jet composition of GRB 210619B. With a measured redshift of z = 1.937, we find that GRB 210619B falls within the 10 most luminous bursts observed by Fermi so far. The energy-resolved prompt emission light curve of GRB 210619B exhibits an extremely bright hard emission pulse followed by softer/longer emission pulses. The low-energy photon index (αpt) values obtained using the time-resolved spectral analysis of the burst suggest a transition between the thermal (during harder pulse) to non-thermal (during softer pulse) outflow. We examine the correlation between spectral parameters and find that both peak energy and αpt exhibit the flux tracking pattern. The late time broad-band photometric data set can be explained within the framework of the external forward shock model with νm < νc < νx (where νm, νc, and νx are the synchrotron peak, cooling-break, and X-ray frequencies, respectively) spectral regime supporting a rarely observed hard electron energy index (p < 2). We find moderate values of host extinction of E(B − V) = 0.14 ± 0.01 mag for the small magellanic cloud extinction law. In addition, we also report late-time optical observations with the 10.4 m Gran Telescopio de Canarias placing deep upper limits for the host galaxy (z = 1.937), favouring a faint, dwarf host for the burst.

Multicomponent, high-intensity, and patient-centered care intervention for complex patients in transitional care: SPICA program.

Multimorbidity is increasingly present in our environment. Besides, this is accompanied by a deterioration of social and environmental conditions and affects the self-care ability and access to health resources, worsening health outcomes and determining a greater complexity of care. Different multidisciplinary and multicomponent programs have been proposed for the care of complex patients around hospital discharge, and patient-centered coordination models may lead to better results than the traditional ones for this type of patient. However, programs with these characteristics have not been systematically implemented in our country, despite the positive results obtained. Hospital Universitario de Canarias cares for patients from the northern area of Tenerife and La Palma, Spain. In this hospital, a multicomponent and high-intensity care program is carried out by a multidisciplinary team (made up of family doctors and nurses together with social workers) with complex patients in the transition of care (SPICA program). The aim of this program is to guarantee social and family reintegration and improve the continuity of primary healthcare for discharged patients, following the patient-centered clinical method. Implementing multidisciplinary and high-intensity programs would improve clinical outcomes and would be cost-effective. This kind of program is directly related to the current clinical governance directions. In addition, as the SPICA program is integrated into a Family and Community Care Teaching Unit for the training of both specialist doctors and specialist nurses, it becomes a place where the specific methodology of those specialties can be carried out in transitional care. During these 22 years of implementation, its continuous quality management system has allowed it to generate an important learning curve and incorporate constant improvements in its work processes and procedures. Currently, research projects are planned to reevaluate the effectiveness of individualized care plans and the cost-effectiveness of the program.

Association of pain intensity and psychological factors among patients with chronic low back pain (LBP). A correlational cross-sectional study

Introduction: Chronic low back pain (cLBP) is associated with a dynamic interaction of multiple psychological factors that act as predictors of recovery time. Our goal was to quantify the association between pain intensity and psychological variables. Material and methods: A cross-sectional study using convenience sampling was conducted at Universidad Europea de Canarias (Spain) between January 24, 2022 and June 10, 2022. In addition, adults and children with cLBP older than 13 years with cLBP for at least 12 weeks of symptoms were included. Finally, the descriptive analysis and the calculation of the correlation coefficients of the data was carried out with SPSS v.28.0. Results: We recruited 146 subjects (n=85 women, 58.3%; n=61 men,41.7%) aged 50.4 ± 12.21 years suffering from cLBP with a moderate pain intensity (7.02±0.188), kinesiophobia (22.79 ± 0.559), catastrophism (13.42 ± 0.897), anxiety (24.47±0.560) and the quality of life SF36-PF (65.65±2.291), SF36-PR (48.03±2.727), SF36-BP (33.14±1.566), SF36-GH (43.98±1.873), SF36-V (48.56±1.812), SF36-SF (61.39±2.353), SF36-ER (76.29±2.043) and SF36-MH (49.76±1.666). Pain intensity in cLBP patients was negatively and moderately correlated with SF36-BP score (Pearson's r = -0.561, p < 0.001). In addition, the main variable was negatively and weakly correlated with SF36-PF (Pearson's r= -0.395, p<.001), SF36-PR (Pearson's r=-0.433, p<.001), SF36-V (Pearson's r = -0.260, p = 0.006), SF36-GH (Pearson's r = -0.203, p=0.032), SF36-SF (Pearson's r=-0.215, p=0.024). and SF36-MH (Pearson's r= -0.203, p = 0.032). Furthermore, pain intensity showed positive and weak with kinesiophobia score (Pearson’s r=0.310, p<.001) and positive and very weak with catastrophism (Pearson’s r=0.136, p<.001). In contrast, there was not correlation between pain intensity and anxiety in cLBP subjects (Pearson’s r=0.025, p=0.794). Conclusions: Psychological variables were not associated with pain intensity in patients with cLBP. However, physical perception of pain was the only variable that remained moderately linearly associated with pain intensity.

Electromagnetic Assessment of UHF-RFID Devices in Healthcare Environment

In this work, the evaluation of electromagnetic effect of Ultra High Frequency Radio Frequency Identification (UHF-RFID) passive tags used in the healthcare environment is presented. In order to evaluate exposure levels caused by EM field (865–868 MHz) of UHF-RFID readers, EM measurements in an anechoic chamber and in a real medical environment (Hospital Universitario de Canarias), as well as simulations by 3D Ray Launching algorithm, and of biophysical exposure effects in human models are presented. The results obtained show that the EM exposure is localized, in close vicinity of RFID reader and inversely proportional to its reading range. The EM exposure levels detected are sufficient to cause EM immunity effects in electronic devices (malfunctions in medical equipment or implants). Moreover, more than negligible direct effects in humans (exceeding relevant SAR values) were found only next to the reader, up to approximately 30% of the reading range. As a consequence, the EM risk could be firstly evaluated based on RFID parameters, but should include an in situ exposure assessment. It requires attention and additional studies, as increased applications of monitoring systems are observed in the healthcare sector—specifically when any system is located close to the workplace that is permanently occupied.

Stellar Populations in type Ia supernova host galaxies at intermediate-high redshift: Star formation and metallicity enrichment histories

ABSTRACT We present a summary of our project that studies galaxies hosting type Ia supernova (SN Ia) at different redshifts. We present Gran Telescopio de Canarias (GTC) optical spectroscopy of six SN Ia host galaxies at redshift z ∼ 0.4–0.5. They are joined to a set of SN Ia host galaxies at intermediate-high redshift, which include galaxies from surveys SDSS and COSMOS. The final sample, after a selection of galaxy spectra in terms of signal-to-noise and other characteristics, consists of 680 galaxies with redshift in the range 0.04 < z < 1. We perform an inverse stellar population synthesis with the code fado to estimate the star formation and enrichment histories of this set of galaxies, simultaneously obtaining their mean stellar age and metallicity and stellar mass. After analysing the correlations among these characteristics, we look for possible dependencies of the Hubble diagram residuals and supernova features (luminosity, colour and strength parameter) on these stellar parameters. We find that the Hubble residuals show a clear dependence on the stellar metallicity weighted by mass with a slope of −0.061 mag dex−1, when represented in logarithmic scale, log 〈ZM/Z⊙〉. This result supports our previous findings obtained from gas oxygen abundances for local and SDSS-survey galaxies. Comparing with other works from the literature that also use the stellar metallicity, we find a similar value, but with more precision and a better significance (2.08 versus ∼ 1.1), due to the higher number of objects and wider range of redshift of our sample.

Spectral Rotational Characterization of the Didymos System prior to the DART Impact* *Based on observations made with the Italian Telescopio Nazionale Galileo (TNG) operated on the island of La Palma by the Fundación Galileo Galilei of the Istituto Nazionale di Astrofisica (INAF) at the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofisica de Canarias (Program AOT42-TAC8).

The smallest member of the Didymos binary near-Earth object system (Dimorphos) is the target of the DART/LICIACube mission, the first attempt to change the orbit of another celestial body via a kinetic impactor. It is important to characterize the unperturbed system prior to the DART impact. In this work we obtained, for the first time, spectral characterization of the system at several rotational phases from TNG+DOLORES in the visible range (0.34–0.81 μm). This is crucial in order to disentangle the primary and secondary bodies and highlight eventual dishomogeneities on their surfaces. We confirm that a subtle but persistent spectral variability appears, even when compared with data obtained from previous 2003 and 2019 apparitions. While the reason for such variability is still under investigation, our analysis hints that different compositions could play a role. Future observations during the brighter 2022 apparition in synergy with data obtained from LUKE on board LICIACube will definitely tackle this conundrum.

P-020 Influence of vanadium and lead in seminal fluid on assisted reproductive techniques

Abstract Study question In recent decades there has been an increase in environmental contaminants than can affect assisted reproduction techniques. We analyze the influence of vanadium (V) and lead (Pb) on these results. Summary answer Higher seminal fluid V levels affect fertilization rate (FR). Higher Pb and V levels decrease embryo cleavage rate (CR). What is known already Some animal studies have shown that V produces toxicity in the male reproductive system through oxidative stress, and this leads to decreases sperm count and motility, as well increased concentration of abnormal sperm. Pb is one of the main pollutants and, it accumulates in the male reproductive organs, deteriorates the quality of semen, increases the frequency of spontaneous abortion and male infertility. And it has also been seen that it inhibits sperm functions in vitro, although its mechanism of action is still unknown. Study design, size, duration A prospective study was conducted in 102 males, with a mean age of 38.0 ± 5.7, attended successively for initial evaluation, in the Human Reproduction Unit of the Hospital Universitario de Canarias, between february and april 2018, who underwent a semen analysis and metal detection and, subsequently, an IVF/ICSI treatment during years 2019 and 2020 (n = 92). The relationship between the presence of metals and the results of ART has been established. Participants/materials, setting, methods We included two groups based on semen parameters: 41 patients with pathological spermiograms (40.2%), while the remaining 61 (59.8%) had a normal semen analysis and constituted the control group.The study of seminal parameters was performed according to the WHO guidelines. The metals analysis was carried out in the Toxicology Area of the Universidad de La Laguna, using the digestion for microwave method. Metal measurement was performed using inductively coupled plasma optical emission spectrometry (ICP-OES). Main results and the role of chance In our study we have observed 79.4% of patients have V in semen. Significant differences have been found in the concentration of V in semen (t100=1.988, p = 0.05), is higher in patients who drink alcohol (0.51± 0.40 mg/Kg) than in abstinent patients (0.35± 0.30 mg/Kg). The group with FR above 75% presented lower V values compared to those with rates below 75% (p = 0.039). Within this last group, 33.3% present V values higher than 0.7 mg / kg compared to 15.8% who present it in the group with FR greater than 75% (OR = 2.67 CI95% 1.01, 7.52; p = 0.048). A statistical relationship was found between CR and Pb and V. Those who did not reach 100% CR presented higher Pb values (p = 0.052). Of them, 63.6% presented Pb compared to 38.5% in the group reaching 100% division. This same relationship was observed for V, with higher values in the group that did not reach 100% (p = 0.032), and V being present in 90.9% of the samples compared to 79.5% in the group reaching 100%. Limitations, reasons for caution The limitation of this study was the volume of semen that could be obtained for the metal detection, only 0.5 ml. This was because the semen sample was used at the same time to make a diagnosis of infertility though a spermiogram Wider implications of the findings The determination of metals in semen opens a new field in the study of infertility, and many cases of unknown infertility could due to metal presence or absence in seminal fluid, with the option of performing several treatments to correct these possible anomalies. Trial registration number not applicable

Photoionized Herbig–Haro objects in the Orion Nebula through deep high-spectral resolution spectroscopy – III. HH 514

ABSTRACT We analyse the physical conditions and chemical composition of the photoionized Herbig–Haro object HH 514, which emerges from the protoplanetary disc (proplyd) 170-337 in the core of the Orion Nebula. We use high-spectral resolution spectroscopy from Ultraviolet and Visual Echelle Spectrograph at the Very Large Telescope and IFU-spectra from MEGARA at the Gran Telescopio de Canarias. We observe two components of HH 514, the jet base and a knot, with $n_{\rm e}= (2.3 \pm 0.1) \times 10^5 \rm{cm}^{-3}$ and $n_{\rm e}= (7 \pm 1) \times 10^4 \rm{ cm}^{-3}$, respectively, both with Te ≈ 9000 K. We show that the chemical composition of HH 514 is consistent with that of the Orion Nebula, except for Fe, Ni, and S, which show higher abundances. The enhanced abundances of Fe and Ni observed in HH objects compared with the general interstellar medium are usually interpreted as destruction of dust grains. The observed sulphur overabundance (more than two times solar) is challenging to explain since the proplyd photoevaporation flow from the same disc shows normal sulphur abundance. If the aforementioned S-overabundance is due to dust destruction, the formation of sulfides and/or other S-bearing dust reservoirs may be linked to planet formation processes in proplyds, which filter large sulfide dust grains during the accretion of matter from the disc to the central star. We also show that published kinematics of molecular emission close to the central star are not consistent with either a disc perpendicular to the optical jet, or with an outflow that is aligned with it.