Listeners demonstrate remarkable flexibility in processing speech under varying conditions, rapidly adapting to acoustically distorted signals like time-compressed speech or speech in noise. Existing research has explored the immediate effects of time-compression and background noise on speech intelligibility, but the impact of these distortions on long-term memory recall for speech content is less well understood. With the growing use of online education platforms where listeners often prefer to use accelerated playback, understanding the effects of time-compression and noise on long-term memory from speech is crucial. Here, we investigated how speech distortions from time-compression influence explicit memory, and how this interacts with background noise. Participants (N = 35) each listened to six recorded lectures at varying time-compression rates (1.0x, 1.5x, 2.0x) and background noise levels (quiet versus babble noise at + 10 dB SNR). After each lecture, participants answered 10 multiple-choice questions probing explicit content recall. Listeners exhibited a significant decline in content recall with increased time compression, while background noise during the lecture did not impact listeners’ content recall. Our findings demonstrate that time-compressed speech negatively affects long-term memory recall, which may arise from the additional cognitive demands necessary to process time-compressed speech, even after perceptual adaptation.