Machine learning (ML)-based in-home electrocardiogram (ECG) systems have emerged as transformative tools, advancing beyond traditional cardiology methods by offering innovative techniques for cardiac care. These systems enable sustained data collection, real-time monitoring of cardiac status, and individualized treatment plans, all while minimizing the need for frequent clinic visits. By leveraging advanced analytics and ML algorithms, in-home ECG systems analyze large-scale datasets to detect patterns and anomalies that might otherwise go unnoticed, providing early alerts and improving patient outcomes. This review examines the latest trends in ML-enhanced in-home ECG technology, emphasizing its functionality in anomaly detection, continuous monitoring, and decision-making processes. The integration of ML not only enhances diagnostic precision but also opens avenues for scalable, personalized, and remote healthcare solutions. Despite these advancements, significant challenges remain, including issues related to data privacy, algorithmic biases, and the reliability of real-world implementations. Addressing these challenges is essential for optimizing the performance and ethical use of these systems. This review also explores opportunities for future research, particularly in improving algorithm robustness and addressing biases to ensure equitable and accurate cardiac care for diverse populations. By integrating state-of-the-art ML techniques, in-home ECG systems are poised to revolutionize contemporary cardiology, reducing healthcare costs and enabling a progressive shift toward accessible, patient-centered care. This comprehensive exploration highlights the potential of ML-based in-home ECG systems to redefine cardiac monitoring and treatment, contributing to the broader transformation of modern healthcare. Received: 13 September 2024 | Revised: 11 December 2024 | Accepted: 31 December 2024 Conflicts of Interest The authors declare that they have no conflicts of interest to this work. Data Availability Statement Data sharing is not applicable to this article as no new data were created or analyzed in this study. Author Contribution Statement Aqsa Bibi: Conceptualization, Methodology, Validation, Formal analysis, Investigation, Resources, Data curation, Writing - original draft, Writing - review & editing, Visualization, Project administration. Jawwad Sami Ur Rahman: Methodology, Validation, Investigation, Resources, Writing - review & editing, Supervision, Project administration.
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