In recent years, the share of renewable energy sources in current energy production has been increasing due to the depletion of fossil fuel resources, increasing energy needs and environmental concerns. Solar energy, one of the most important renewable energy sources depending on being clean, sustainable and environmentally friendly energy source. Understanding the solar radiation value is crucial for maximizing the potential of solar energy and ensuring the efficient operation of solar energy systems. In this paper, it is aimed to develop a new global solar radiation (GSR) prediction model by using simulated annealing algorithm (SAA). Modeling solar radiation data with significant variability is a challenging task that necessitates the use of nonlinear approaches. Although the SAA is widely used in engineering and natural sciences, it has not previously been used to develop a GSR prediction model. While developing the SAA forecast model for the Adana region, long-term sunshine duration and solar radiation data obtained from the Turkish General Directorate of State Meteorology were used, as well as geographical features such as latitude and longitude of the selected region. The performance and applicability of the proposed model was examined by comparing it with different GSR estimation methods developed in the literature. The primary contribution of this study lies in the introduction of an inventive model, which has been constructed for the first time in the assessment of GSR, to the current collection of literature. The produced results were statistically compared with the observed data using six separate performance and error measures. The results of all years showed that the relative percentage error (RPE) less than 11.66 %, the mean percentage error (MPE) does not exceed 12.55 %, the correlation coefficient (R2) greater than 0.98, the mean absolute percentage error (MAPE) test results appear to vary close to the value 10, the sum of squared relative error (SSRE) test results seem to approaching 0 and the t-statistic test less than 4.06 for the annual GSR. It has been observed that the developed SAA GSR forecasting model has a successful performance when compared to different forecasting models popularly used in the literature. According to the statistical error results, the estimated GSR data from the novel SAA-GSR forecast model aligns well with the measured meteorological values. Given the efficacy of the established SAA model in GSR estimation, this study is anticipated to offer valuable insights and contributions to the application of the SAA approach in other energy applications.