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Articles published on Dandruff

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  • Research Article
  • 10.1177/12034754251368845
Understanding the Scalp: Dandruff and Seborrheic Dermatitis.
  • Oct 24, 2025
  • Journal of cutaneous medicine and surgery
  • Aditya K Gupta + 9 more

Dandruff (DF) and seborrheic dermatitis (SD) are prevalent, chronic scalp disorders that affect a large portion of the global population, often leading to significant psychological distress and quality-of-life impairment. While DF is a milder form characterized by mild scaling, itching, and no visible inflammation, SD presents as a more severe condition with red, scaly, and often inflamed lesions. Despite the high prevalence of these conditions, research specific to their epidemiology and management in Canada remains limited. This review examines the etiology, epidemiology, and management of DF and SD from a Canadian perspective. It highlights the role of Malassezia species in the pathogenesis of both conditions and explores the influence of genetic, environmental, and microbial factors. The review also outlines the diverse clinical presentations of DF and SD across different ethnicities and the effectiveness of various over-the-counter and prescription treatments available. Additionally, the article emphasizes the lack of a Canadian consensus on the management of these conditions, calling for further research and formalized guidelines to better inform health care providers and improve patient care. Given the diverse Canadian population and the increasing burden of DF and SD, a more tailored approach to treatment is essential to address the challenges posed by these chronic conditions.

  • Research Article
  • 10.33761/jsm.v20i1.1802
Efektivitas Produk Herbal Antijamur untuk Terapi Ketombe (Pityarisis capitis): Literature Review dan Analisis Bibliometrik
  • Jun 30, 2025
  • Jurnal Sehat Mandiri
  • Esti Syahrin + 2 more

Dandruff (Pityriasis capitis) is a skin health problem caused by fungal growth on the scalp, increased production of oil glands (sebum) excessively. Current advances in science and technology have led to the development of herbal plant research to be used as antifungal herbal products in overcoming dandruff. The purpose of this literature review is to review and summarize herbal plants that have the potential to inhibit the growth of fungi that cause dandruff, so that it is useful to be developed as further research. Article searches were conducted from February to May 2024 using the Publish or Perish reference manager (PoP) tool in the Google scholar database source which was then term mapped in the Vosviewer software. The results of original research journal publications related to dandruff published in the range of 2014 to 2024 were obtained as many as 12 journals. The conclusion obtained in this literature review is that secondary metabolite compounds contained in herbal plants have a potential fungal inhibition mechanism, so it is appropriate to be developed in future research and used as an antifungal herbal product to treat dandruff.

  • Research Article
  • 10.18203/issn.2455-4529.intjresdermatol20252078
Expert opinion on management of Pityriasis capitis (dandruff) and related scalp conditions in clinical practice
  • Jun 27, 2025
  • International Journal of Research in Dermatology
  • Sanjiv Kandhari + 3 more

Dandruff and related scalp conditions, including seborrhoeic dermatitis (SD), scalp psoriasis, folliculitis, pityriasis versicolor (PV) and acne vulgaris (AV), are common globally. Dandruff, caused by Malassezia fungi, leads to excessive scalp skin shedding, whereas SD can vary in severity. Scalp psoriasis presents with chronic inflammation and scaly plaques. PV is a benign fungal infection that affects the trunk and neck, whereas AV primarily impacts the face and can also appear on the body. Both acne and dandruff are associated with imbalances in the skin and gut microbiome and altered immune responses. Treatments range from topical antifungals and anti-inflammatories to systemic therapies. The key active ingredients such as Selenium sulphide (SS), Zinc pyrithione (ZPT), Coal tar, Salicylic acid, Ketoconazole, Ciclopirox and Clobetasol are commonly employed in antidandruff formulations. Comparative studies suggest SS has a superior anti-dandruff effect compared with ZPT and coal tar. SS is effective against fungal infections, cost-efficient and has minimal side effects. In chronic and recurrent conditions, the use of SS in maintenance therapy can significantly lower treatment costs. This makes it a practical choice for long-term management. The current study presents the consensus statements derived from focused group discussions held across various regions of India between March and September 2023 concerning clinical strategies for the management of dandruff and related dermatological conditions.

  • Research Article
  • 10.4314/njpr.v20i2.3
Formulation and Evaluation of Natural-based Cosmeceutical Ointments: An Approach to Manage Dry Scalp Dandruff
  • Feb 7, 2025
  • Nigerian Journal of Pharmaceutical Research
  • K.S Salako + 2 more

Background: Pityriasis capitis, commonly known as dandruff, is a prevalent, chronic scalp ailment that affects over half of the world's population. Dry scalp dandruff is a type of dandruff. Ointments are good examples of pharmacological formulations that have emollient effects on the scalp and hair. Thus, this study aimed at formulating cosmeceutical herbal ointment as an approach to manage dry scalp dandruff disorder.Methods: Phytochemical screening of Amla (Phyllanthus emblica Linn., family- Euphorbiaceae) powder and Avocado (Persea americana Mill., family- Lauraceae) oil was carried out. The ointments were formulated using shea butter as base. Physicochemical, cosmeceutical (conditioning) evaluations, draize skin irritancy test, and stability studies were also carried out.Results: The natural-based ointment formulations were cream to brown in colour, the formulations had flowery smell, smooth and oily to gritty and dry texture, pH range of 4.8-7.4. Viscosity was in the range of 20433 to 28007 cp. Spreadability was in the range of 28.49 to 85.24 g.cm/sec. Loss on drying was in the range of 1.77 to 6.73 %. Globule size was in the range of 0.2 – 2.0 µm. The cosmeceutical or conditioning evaluation showed the average score for shine /oiliness, softness and washability to be 2.6 to 4.6, 2.6 to 3.6 and 3.0 respectively. Draize skin irritancy test showed that there was no inflammation, oedema and erythema observed. The formulations exhibited stability in terms of colour, smell, texture and there was no syneresis observed, but there was a difference in the pH (4.96-7.02) of all the formulations.Conclusion: This study has shown that natural based cosmeceutical herbal ointment formulations may be used in managing dry scalp dandruff disorder through its conditioning activities.

  • Open Access Icon
  • Research Article
  • 10.32539/bji.v11i1.209
The Relationship Between Personal Hair Hygiene and The Incidence of Pityriasis Capitis in Students at Faculty of Medicine, Baiturrahmah University
  • Feb 4, 2025
  • Biomedical Journal of Indonesia
  • Marsa Qalbina Abdi + 2 more

Introduction. Pityriasis capitis or commonly known as dandruff, pityriasis sicca, pityriasis simplex is a disorder resulting from mild inflammation caused by excessive exfoliation of the stratum corneum which is characterized by the presence of white-gray flakes on the scalp and hair shaft. Personal hygiene, including self-care carried out by a person to protect and maintain their health. Aim the research to the relationship between personal hair hygiene and the incidence of pityriasis capitis in students at Faculty of Medicine, Baiturrahmah University. Methods. This study is quantitative research that applies an analytical approach by design cross-sectional. The research participants came from students at the Faculty of Medicine, Baiturrahmah University and total of 108 samples were selected using techniques consecutive sampling. The data in this study is primary data obtained from the results of questionnaires and scalp observations. Data analysis used SPSS version 25 and the test used was chi-square test. Results. Students who experience pityriasis capitis are 66 people (61.1%) with the largest gender experience it being women, namely 46 people (42.6%). Personal hair hygiene of students are in the medium category, namely 76 students (70.4%). There is a relationship between personal hair hygiene and the incidence of pityriasis capitis with a p-value of 0.029 (p<0.05). Conclusion. There is a relationship between personal hair hygiene and the incidence of pityriasis capitis in students at the Faculty of Medicine, Baiturrahmah University.

  • Open Access Icon
  • Research Article
  • 10.36713/epra20013
SEBORRHEIC DERMATITIS, SCOPING REVIEW
  • Feb 1, 2025
  • EPRA International Journal of Multidisciplinary Research (IJMR)
  • Ana Belén Valero Martillo + 5 more

Introduction: Seborrheic dermatitis (SD) is a common skin disease, where its signs and symptoms may differ according to skin color, associated medical conditions, environmental factors, and vehicle preference. Seborrheic dermatitis is a common skin condition in infants, adolescents and adults, characterized by scaling, erythema and itching, especially on the scalp, face, chest, back, armpits and groin. Objective: to detail the current information related to seborrheic dermatitis, etiology, epidemiology, pathophysiology, histopathology, clinical presentation, evaluation, differential diagnosis, treatment and prognosis. Methodology: a total of 29 articles were analyzed in this review, including review and original articles, as well as clinical cases, of which 23 bibliographies were used because the other articles were not relevant for this study. The sources of information were PubMed, Google Scholar and Cochrane; the terms used to search for information in Spanish, Portuguese and English were: sebopsoriasis, seborrheic dermatitis, seborrheic eczema, dandruff and pityriasis capitis. Results: The most relevant results indicate that seborrheic dermatitis has a significant global prevalence, affecting up to 5% of the population, with a higher incidence in individuals with HIV-AIDS. Its pathogenesis has been identified as involving a combination of factors, including Malassezia spp. colonization of the skin, alteration of the cutaneous microbiota and a deregulated immune response. The most effective treatments are topical, particularly antifungal agents such as ketoconazole and low potency corticosteroids, although treatment should be tailored to the individual characteristics of each patient. Despite being a chronic disease in many cases, early diagnosis and proper management allow control of symptoms and improve the quality of life of patients. Conclusions: Seborrheic dermatitis is a common skin disease, with significant prevalence in various ages and groups, especially in people with HIV-AIDS. Its pathogenesis involves factors such as colonization by Malassezia spp, alterations in the cutaneous microbiota and immune dysregulation. Although it may be self-limiting in some cases, in others it presents a chronic course with relapses. The most effective treatment includes topical antifungal and anti-inflammatory agents, adapted to the severity and location of the lesions. Early diagnosis and appropriate treatment are key to control symptoms and improve the quality of life of patients. KEY WORDS: dermatitis, seborrheic, eczema, skin.

  • Open Access Icon
  • Research Article
  • 10.1186/s13568-024-01818-w
Anti-furfurative comparison of Kesh Kanti-Herbal Shampoos and synthetic shampoos against Malassezia furfur for dandruff management
  • Jan 13, 2025
  • AMB Express
  • Acharya Balkrishna + 4 more

Malassezia furfur is the primary etiological agent of dandruff (Pityriasis capitis). Although herbal shampoos are preferred for their natural, mild ingredients over synthetic counterparts, they are often perceived as less effective in managing flaky scalp conditions or furfuration causing dandruff. The study compares the antifungal efficacy of herbal and synthetic shampoos against M. furfur. Seven shampoos including herbal (HS_Adv, HS_M&P, HS_Aloe), synthetic (SYN_01, SYN_02, SYN_03) and an antifungal shampoo containing ketoconazole (KETO) were employed in the study. Experiments were designed to stimulate real-world conditions, utilizing disc-diffusion assay, 3-minute shampoo contact at mild dilutions (1% and 5%), recurrent 3-minute shampoo contact every 24 h with intermittent recovery. Both disc diffusion and 3-minute shampoo contact demonstrated that all shampoos were effectively inhibiting the viability of M. furfur. However, a single 3-minute shampoo contact followed by a prolonged recovery of 72 h revealed SYN_01 and KETO with maximal antifungal action. In contrast, herbal shampoos were as effective as synthetic options when M. furfur was subjected to 3-minute shampoo contact every 24 h with intermittent recovery. Comprehensive ingredient analysis revealed the robust antifungal activity in SYN_01 was probably because of the presence of various surfactants, allergens and a potent synthetic antifungal agent, Piroctone olamine. This study experimentally demonstrates that herbal shampoos are as effective as synthetic options in managing M. furfur-induced dandruff when applied consistently. The findings highlight the importance of regular scalp cleansing for dandruff management and provide valuable insights into the antifungal potential of both herbal and synthetic formulations.

  • Open Access Icon
  • Research Article
  • 10.18579/jopcr/v23.3.79
Mexican Mint (Coleus amboinicus) Emulgel: Natural Solution for Antidandruff Hair Care
  • Nov 26, 2024
  • Journal of Pharmaceutical Research
  • Sakshi Shetty + 2 more

Today, the world is developing more and more in all sectors at a faster pace. But with all these developments, people are more prone to falling ill due to factors such as pollution, unhealthy lifestyles, busy work schedules, etc. Nowadays, even children suffer from the issue of dandruff and scalp infections which in later teenage years leads to unhealthy scalp and hair fall problems. Dandruff is a common scalp condition that affects individuals of all ages. It not only causes discomfort but also undermines hair health and aesthetics. Although scalp disorders are not among those that cause severe physical illness or morbidity yet are of great social concern. Scalp and hair conditions have more of a psychological impact on societies. Even minor changes in hair like graying of hair, affects the self-confidence and self-esteem of an individual. There are many types of medications and formulations to treat hair dandruff issues, one of which includes a novel drug delivery system such as “Emulgel” in the form of a mask. The anti-dandruff hair mask offers multiple benefits, including reduction in scalp inflammation and effective management of hair dandruff problems. Furthermore, it rejuvenates the scalp and nourishes hair follicles due to its natural vitamins and nutrient content. Keywords: Dandruff, Pityriasis capitis, Seborrheic dermatitis, Mexican mint, Herbal hair mask, Hair mask

  • Open Access Icon
  • Research Article
  • 10.3126/ajms.v15i2.58486
Prevalence of skin diseases among hostellers attending the tertiary care hospital
  • Feb 1, 2024
  • Asian Journal of Medical Sciences
  • Abirami P + 1 more

Background: Skin diseases are more common but are mostly non-fatal and chronic. Dermatological conditions account for a significant proportion of the global burden of diseases. Aims and Objectives: The study aimed to determine the prevalence of skin diseases among hostellers, determine the causative factors, and describe the prevention. Materials and Methods: This cross-sectional study was conducted for 2 months in the outpatient Department of Dermatology, Government Medical College, Pudukottai, on 507 hostellers. The study subjects were examined and diagnosed by the dermatologist. Questions such as exposure to sunlight, usage of sunscreen, frequency of head baths, and junk food consumption were asked and recorded in a case study form by the principal investigator. Results: Pityriasis capitis was the most prevalent skin disease among 507 participants, followed by acne vulgaris (54.83%) and pediculosis capitis (25.64%). Pityriasis capitis is more common in men (56.17%), with higher chances in those with head baths (<3 times/week) and exposure to sunlight (28.08%). Acne vulgaris affects both males and females equally; face washing <3 times daily is associated with oil and sebum retention, while lack of sunscreen and junk food intake are linked. Periorbital melanosis is more prevalent in females (54.62%) and is linked to stress (66.39%). Sleep duration is also a factor, with 69.23% of girls having a history of cosmetic usage. Conclusion: Pityriasis capitis, acne vulgaris, pediculosis capitis, dermatophytosis, and periorbital melanosis are common skin diseases caused by sharing, sleep deprivation, stress, and poor hygiene. Proper hygiene, sleep patterns, and self-care can reduce skin disease incidence.

  • Research Article
  • 10.53879/id.60.04.12872
TAMPOO AS A NOVEL ANTIDANDRUFF FORMULATION
  • Apr 28, 2023
  • INDIAN DRUGS
  • Vivek J Naik + 5 more

Pityriasis capitis commonly known as dandruff, is an un-inflamed or mildly inflamed form of seborrheic dermatitis and appears as bran-like scaly patches scattered within hair bearing areas of the scalp and which could result in scaly itchy skin of the scalp. The present research work was carried out to develop tampoo. Tampoo is a novel solid dosage antidandruff formulation loaded with ketoconazole, prepared by direct compression technique having ease of manufacturability, improved stability and which becomes shampoo after aqueous dispersion, the moment it comes in contact with water. The combination of elastic and plastic materials, viz gaur gum and dibasic calcium phosphate in appropriate proportions was used to compress poorly compressible sodium lauryl sulphate. Tapmoos were compressed using direct compression method and evaluated for effect of filler binder, foam booster and disintegrating agents. Based on the results obtained, it was found that formulation F6 containing surface active agent (sodium lauryl sulphate) and foam booster (gaur gum) imparts acceptable pharmaceutical properties.

  • Open Access Icon
  • Research Article
  • 10.55324/enrichment.v1i1.2
The Relationship of Stress Level to the Incidence of Pityriasis Capitis (Dandruff) in Students at SMK Panca Karsa Sungai Pinyuh
  • Apr 27, 2023
  • Enrichment: Journal of Multidisciplinary Research and Development
  • Amalia Putri S + 2 more

Stress is a condition of disturbing the balance of organisms that involves physiological or psychological tension caused by internal or external factors. Stress is one of the factors that can trigger the incidence of Pityriasis capitis. The level of stress is closely related to the high activity of sebaceous glands which results in changes in temperature and humidity on the scalp. To know the relationship between stress level with the incidence of Pityriasis capitis (dandruff) among female student of Vocational and Pre-Professional High School Panca Karsa Sungai Pinyuh. Observational analytic research with approach design research type cross-sectional. A total of 50 people was involved in this experiment. Independent variable was stress level, and dependent variable was Pityriasis capitis (dandruff) incidence among female students at Vocational and Pre-Professional high school Panca Karsa Sungai Pinyuh. From 50 people, it was found that Pityriasis capitis occurred respondents with normal stress level about 42,9%. The results of the Kolmogorov-Smirnov comparative test showed a significance value of p = 0.591 (p> 0.05) indicating that there was no significant relationship between stress level and Pityriasis capitis (dandruff). There is no relationship between the level of stress with the incidence of Pityriasis Capitis (dandruff) among female students at Vocational and Pre-Professional high school Panca Karsa Sungai Pinyuh.

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  • Research Article
  • 10.4314/njp.v49i4.2
Dermatological disorders and dermatology-specific quality of life among secondary students in public and private schools in Kwara state, Nigeria
  • Apr 21, 2023
  • Nigerian Journal of Paediatrics
  • Jadesola Tryphena Oyedepo + 2 more

Introduction: Skin problems are very common and often affect people in very visible places leading to significant physical and psychological distress. Adolescents go through physiologic changes in their body during puberty with associated psychosocial changes. Having to live with skin disorders during these years can have life-long impact. This study aimed to describe the spectrum of skin disorders in adolescents attending secondary schools in Kwara state and evaluate the dermatology-specific quality of life of those affected by skin disorders.
 Objective: To describe the spectrum of skin disorders among adolescents in secondary schools and evaluate the impact of skin disorders on the dermatology-specific quality of life of those affected.
 Methods: This was a descriptive cross-sectional study. We examined 1000 students from 16 public and private secondary schools in Ilorin, Kwara state. Participant selection was done using a multi- staged stratified random sampling method. The impact on quality of life was evaluated with the Children’s Dermatology Life Quality Index (CDLQI) to determine their dermatology-specific Quality of life. Data obtained was analyzed with SPSS version 20 and was presented using tables and figures.
 Results: The prevalence of skin disease in the study population was 68.4%. The most common skin disorders in order of decreasing frequency were: acne, pityriasisversicolor, dermatophytoses (Including tinea capits, tinea corporis, tinea pedis, tinea unguium and tinea cruris), pityriasis capitis and traction alopecia. About three- quarters of those with skin disease reported an effect on their quality of life. The most frequent effect on Qol was attributed to the symptoms and feelings elicited by skin disease.
 Discussion: This study found a high prevalence of skin disease in adolescents with most of them reporting an effect on their quality of life resulting from their skin problem however this was mostly a mild effect.

  • Research Article
  • Cite Count Icon 1
  • 10.4103/jism.jism_103_22
A clinical study to assess the effect of Priyaladi lepa in Darunaka (Pityriasis capitis)
  • Apr 1, 2023
  • Journal of Indian System of Medicine
  • Smitha Jain + 1 more

Background: Darunaka is one of the Shirah-kapalagata Roga (head and skull diseases) and Kshudra Roga (minor ailments), characterized by Kandu (itching), Rukshata (dryness), Twak-sphutana (scaling), and Kesha-chyuti (hair fall). The clinical features correlate to Pityriasis simplex capitis (dandruff), which is a common condition that causes itchy, scaly skin on the scalp with high prevalence in the general adult population. Ayurveda emphasizes various Lepa Kalpana (semisolid medicaments used for external application) for Darunaka; Priyaladi lepa is one among them. As there is ambiguity about successful dandruff treatment due to its severity and frequent relapses, it necessitates finding an effective and safe topical antidandruff agent. Aim: To assess the effect of Priyaladi lepa in the management of Darunaka. Materials and Methods: Study was intended as an open-label, nonrandomized, single-arm, interventional trial. Thirty subjects were treated with the application of Priyaladi lepa on the scalp weekly twice for consecutive 2 weeks. Results: Overall results showed a decline in the severity of symptoms such as itching, dryness of scalp, cracking, and scaling of scalp as assessed with a five-point Likert scale. Conclusion: Application of Priyaladi lepa on the scalp showed a highly significant effect in pacifying the symptoms of Darunaka, and a marked reduction in clinical symptoms was well appreciated with four applications. There were no topical and systemic adverse drug effects noted at the end of the study.

  • Open Access Icon
  • Research Article
  • 10.18203/2394-6040.ijcmph20230920
A cross sectional study on health status of adolescents in urban field practice area of tertiary care hospital in central India
  • Mar 29, 2023
  • International Journal Of Community Medicine And Public Health
  • Ashish T Nimje + 3 more

Background: Adolescence is defined by WHO as the age group of 10-19 years. In India, adolescents (10-19 years) constitute about 21.4 percent of the population, comprising one fifth of the total population. Adolescents are apparently healthy people but they may also have various kinds of problems. If they are to reach adulthood in a healthy state, then it’s necessary to analyze the common health problems prevalent in this age-group so that targeted and concerted services could be provided to them. Objective of current study was to assess the health status of adolescents in urban field practice area of tertiary care hospital in Central India. Methods: A community based descriptive cross-sectional study was conducted in urban field practice area of Government Medical College and Hospital Nagpur. House to house survey was conducted among 330 adolescents out of which 214 (64.84%) were male and 116 (35.16%) were female. Results: In present study most common morbidity found was dandruff in 127 (38.48%) adolescents followed by acne vulgaris in 102 (30.90%). Anemia was present in 52 (15.75%) of study subjects. Out of 237 morbid study subject, 114 (48.10%) study subjects had single morbidity followed by 2 and 3 morbidities in 52 (21.94%) and 63 (26.59%) respectively. About 8 (3.37%) study subjects had more than 3 morbidities. Conclusions: The present study shows that adolescents experience various health problems. Predominant morbidities observed in study subjects are dandruff (pityriasis capitis), acne vulgaris, anaemia, dental carries.

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  • Research Article
  • Cite Count Icon 3
  • 10.22159/ijap.2022.v14ti.37
STUDIES ON POLY HERBAL POWDER SHAMPOO FOR THE TREATMENT OF PEDICULOSIS CAPITIS AND PITYRIASIS CAPITIS INFESTATIONS
  • Jul 28, 2022
  • International Journal of Applied Pharmaceutics
  • Jamal Moideen Muthu Mohamed + 5 more

Objective: The main objective of this study was to the formulation containing polyherbal medicinal plants, which gives safety, and efficacy; rectify skin disease, scalp disorders and reducing the harmful effect from herbal anti-lice and dandruff shampoos for the treatment of Pediculosis capitis and Pityriasis capitis and to prevent hair fall. Methods: The formulation of herbal shampoo with various herbal ingredients were dried, milled, sieved (120#) and mixed in geometrical order and evaluated their physicochemical characteristics. Furthermore, particle characters, organoleptic properties, foaming index, skin irritation study, and Anti-lice activity were performed. Results: The prepared poly herbal powdered shampoo (PHPS) exhibits that was freely soluble, particle 20-25 μm size range and free-flowing powder. Lest moisture content (2.5%), ash value, acid value and reduced surface tension of liquid are referred as an ideal candidate for foaming, anti-lice potential with no skin irritations. Conclusion: Based on the evaluation parameters, the prepared powdered shampoo helps to remove hair grease, no hair fall and strengthen hair follicles. Preparation of PHPS formulation at laboratory scale and the compounding of several ingredients of herbal source have produced it possible to ensure safety, efficacy and secure highly effective PHPS.

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  • Research Article
  • Cite Count Icon 1
  • 10.7897/2277-4343.1205143
A SYNOPTIC REVIEW ON PRIYALADI LEPA: AN AYURVEDIC TOPICAL FORMULATION FOR THE MANAGEMENT OF DARUNAKA (DANDRUFF)
  • Oct 15, 2021
  • International Journal of Research in Ayurveda and Pharmacy
  • Puliyur Kannan Mahalakshmi + 1 more

Pityriasis capitis commonly known as Dandruff is a common skin disorder that mainly affects the scalp. It is one of the most common cosmetic problems. It is more likely a social stigma and affects the aesthetic value of a person. In Ayurveda, Acharya Sushruta mentions Darunaka (dandruff) under Kshudra kushta roga (minor skin ailment) and some other authors mention it as Shirah-Kapalagata roga (head and skull diseases). Symptoms of Darunaka are kandu (itching), Keshachyuti (hair fall), Twaksphutana (scaling) and rukshata (dryness). Darunaka can be closely co-related to Pityriasis capitis. Though not being a life-threatening disease, it is affecting almost half of the population from pre-pubertal age to old age of any gender with recurrence and frequent relapses. Ayurveda classics majorly emphasizes the bahya lepa upachaar (external paste application) as a line of treatment in Darunaka. Priyaladi lepa is one such formulation recommended in Sharangadhara Samhitha for Darunaka chikitsa, but not often applied in routine Ayurvedic practice. So, this study aims to appraise the pharmacological activity of the formulation Priyaladi lepa regarding its anti-dandruff efficacy. Rasapanchaka and Dosha karma (Ayurvedic Pharmacological attributes) of ingredients were compiled from Bhavaprakasha Nighantu and other Ayurvedic literature. Pharmacological actions were compiled from original research articles from Google Scholar, Research Gate and PubMed etc. research databases. A study on each ingredient of Priyaladi lepa collectively demonstrated anti-inflammatory, anti-fungal, anti-microbial, anti-pruritic, antioxidant and exfoliation effects. These pharmacological activities encourage further research and henceforth to utilize the same for the effective management of Darunaka (Dandruff).

  • Open Access Icon
  • Research Article
  • Cite Count Icon 70
  • 10.1111/exd.14450
Skin microbiome alterations in seborrheic dermatitis and dandruff: A systematic review.
  • Aug 27, 2021
  • Experimental Dermatology
  • Rong Tao + 2 more

Seborrheic dermatitis (SD) and dandruff (DF) are common chronic inflammatory skin diseases characterized by recurrent greasy scales, sometimes with erythema and itchiness. Although the exact pathophysiology of the disease is still unclear, current theories highlight the role of microbes on the skin surface in the pathogenesis of SD. Here, we conducted a systematic review to investigate the skin microbiome alterations in patients with SD/DF. We searched Medline/PubMed, Embase and Web of Science for research studies published in English between 1January 2000 and 31 December 2020. A total of 12studies with 706 SD/DF samples and 379healthy samples were included in this study. The scalp and face were predominated by the fungi of Ascomycota and Basidiomycota and the bacteria of Actinobacteria and Firmicutes. In general, the included studies demonstrated an increased Malassezia restricta/Malassezia globosa ratio and a reduction in the Cutibaterium/Staphylococcus ratio in the setting of SD/DF. Staphylococcus was associated with epidermal barrier damage, including elevated levels of trans-epidermal water loss and pH, while Cutibacterium had a positive correlation with water content. Malassezia was also found to be related to an increased itching score and disease severity. Further studies focusing on the interactions between various microbes and the host and microbes can help us to better understand the pathogenesis of SD/DF.

  • Open Access Icon
  • Research Article
  • 10.18231/2394-5478.2018.0098
A study on malassezia species causing superficial infections among patients attending a tertiary care hospital in Puducherry
  • Dec 15, 2020
  • Indian Journal of Microbiology Research
  • Swapna M + 2 more

Introduction: Malassezia are normal resident flora in humans and are opportunistic in nature. Superficial infections caused by Malassezia include pityriasis versicolor, pityriasis capitis (dandruff), seborrheic dermatitis and folliculitis. Though the manifestations due to Malassezia are trivial, chronicity and recurrence of lesions are associated with social embarrassment and decreased self-esteem. Aims and Objectives: The primary aim of the study was to detect the prevalence of Malassezia among superficial skin and scalp lesions. It also aims to compare Wood’s lamp examination, KOH mount examination and culture for the diagnosis of Malassezia and study the percentage of various species of Malassezia responsible for superficial infections of skin and scalp. Materials and Methods: One hundred samples collected from patients attending the Dermatology outpatient room with superficial infections of skin and scalp. Patients attending Dermatology outpatient room with complaints of hypopigmented / hyperpigmented / erythematous, scaly skin patches and patients attending Dermatology OP with complaints of itchy / non itchy scaly flakes of scalp (dandruff) were included in the study. Results: Among the 100 samples, 77% were Wood’s lamp positive, 64% were KOH positive and 59% yielded growth of Malassezia in culture. Overall prevalence of Malassezia in our study was 59%. In our study, M. globosa was the commonest species (57.62%) followed by M. furfur and M. sympodialis. Conclusion: Prevalence of Malassezia was 59% in our study. Wood’s lamp examination and KOH mount showed more positivity than culture. M. globosa was the most common species in the study. Wood’s lamp and KOH mount can be used for diagnosis of Malassezia in resource poor settings. But culture and speciation should be performed wherever possible to avoid treatment failure and recurrences. Keywords: Culture, Malassezia, Potassium hydroxide mount, Skin scrapings, Wood’s lamp.

  • Research Article
  • Cite Count Icon 15
  • 10.1111/jocd.13488
Pityriasis capitis: Causes, pathophysiology, current modalities, and future approach
  • May 28, 2020
  • Journal of Cosmetic Dermatology
  • Umang Sheth + 1 more

Pityriasis capitis commonly known as dandruff is one of the most common and widely seen dermatological disease that affects majority of the world population. It is more than superficial flaking, as it leads to significant structural changes in the stratum corneum and inflammatory biomarkers. Various intrinsic and extrinsic factors, such as Malassezia yeast, host epidermal conditions, sebaceous secretion, and abnormal immune responses, are found to contribute to the pathogenesis. Regardless of wide research, detail understanding, and treatment modalities, it still remains to be a cause of concern due to its recurring nature. The objective of this study is to enhance the understanding of its wide causes, pathophysiology, current treatment, and future approach. The article also aims at evaluating various promising anti-dandruff agents that can be further researched to become the leads in anti-dandruff therapy. The article summarizes the current knowledge on dandruff and present new facts and evidences in order to spread awareness, create potential for new herbal treatment options, and effectively control the most commercially exploited scalp disorder.

  • Open Access Icon
  • Research Article
  • Cite Count Icon 11
  • 10.11604/pamj.2020.36.36.21089
Cutaneous disorders of adolescence among Nigerian secondary school students.
  • May 27, 2020
  • The Pan African medical journal
  • Jadesola Tryphena Oyedepo + 2 more

IntroductionA community-based, age-specific survey of skin disorders is usually necessary to characterize the true burden of skin disease among a given population and help to tailor health care personnel training and delivery towards the prevalent disorders in resource poor settings.MethodsThis was a descriptive cross-sectional study among adolescents attending secondary schools in Ilorin, Kwara State, Nigeria. A thousand and three hundred students were recruited from public and private secondary schools through a multi-staged stratified random sampling method. Information was obtained via a semi-structured questionnaire and all students underwent a physical examination. Data was analysed using SPSS version 20. Information generated was presented with tables and figures.ResultsThe prevalence of skin disease in the study was 66.5%. More females, mid-adolescents, students in senior class and those attending public schools had skin disorders. The most prevalent skin disease were: acne vulgaris, pityriasis versicolor, tinea capitis, pityriasis capitis and traction alopecia.ConclusionSkin conditions are highly prevalent among the adolescent population. Infective and inflammatory skin conditions appear to be more prevalent than other classes. Most times, only a few skin disorders account for the bulk of dermatoses affecting this age group. Adolescent skin healthcare should be subsidized because of the high prevalence of skin disorders in this age group.

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