The control–structure interaction (CSI) affects the performance and robustness of protective structures in active control system, and it is important to consider the CSI effect to achieve high performance in structural vibration control. In this paper, the electro-mechanical model of the torsional servomotor is derived by establishing dynamic voltage equilibrium equation. Three different active control models (non-CSI, reduced-order CSI, and higher-order CSI model) which considering different accuracy requirements of the electro-mechanical relationship are established to investigate the influence of the CSI on active tuned mass damper (ATMD) control system. The frequency- and time-domain responses of a three-story steel frame structure during different excitations are investigated, and as a comparison, the responses of the uncontrolled and tuned mass damper (TMD) control system are also studied. It can be concluded that the control performance of the active control system is reduced due to the CSI effect, especially at resonance frequency region of the structure (around 2.7 Hz, 8.2 Hz, and 13.2 Hz). The input voltage, velocity of the top floor, velocity of active mass, and higher-order of control forces have an important influence on the servomotor output control force. Furthermore, it can be found that, to achieve the same control effect, the required control voltage has been significantly increased due to the CSI effect.