Damage tolerance assessment requires the accurate prediction of fatigue crack growth lives. Numerical simulation techniques using mixed mode Paris' law and various equivalent stress intensity factor models (ΔKeq) are widely employed for fatigue life prediction. In the present work, mixed mode (I/II) fatigue crack growth experiments are performed using the compact tension shear specimens made of AISI 316 austenitic stainless steel for various loading angles. Finite element fatigue crack growth simulations are carried out, and the effect of ΔKeq model in fatigue life prediction is studied. To achieve this, a three parameter double exponential type best fit is proposed for fitting the experimental mixed mode crack length vs fatigue life. The performance and capability of various selected models are assessed by comparing the predicted life with the experimental results. Fractographic studies at different stages of crack propagation for different loading angles are also presented to aid the above assessments. Based on the overall consistent performance, Irwin's and Tanaka models are predicting life close to the experimental data and Richard's and Yan's models provide conservative solutions.