Machine performance in industry has a vital role in the production floor. The machine operates smoothly will support the achievement of production targets. One sector produces packaging products made based on plastic experiencing a failure production process due to the frequent stopping of the Blow Molding Machine. Fishbone diagram and Failure Mode and Effect Analysis (FMEA) is used to find information about the factors cause the Blow Molding Machine to stop. Fishbone diagram is used to determine the factors cause the failure of the Blow Molding Machine in running the production process. FMEA is used to identify the factors causing loss and determine the priority level of risk based on the RPN value. The mold damage factor has the highest RPN value. Mold failure is most significant cause of Blow Molding Machine stops operating. The mold is damaged when stored in the spare part warehouse due to crushed by a material made of metal. Mold is stored in an unsuitable location. Analysis using a fishbone diagram to determine the root of the problem handled.