Daily Water Intake Research Articles

Placental Fatty Acid Metabolism and Transport in a Rat Model of Gestational Diabetes Mellitus.

Gestational diabetes mellitus (GDM) is a form of heightened insulin resistance triggered during gestation. This study examines how insulin resistance alters placental long-chain polyunsaturated fatty acid (LCPUFA) transport and metabolism in a rat model of lean GDM. Pregnant Sprague Dawley rats were administered with S961, an insulin receptor antagonist (30 nmol/kg s.c. daily), or vehicle from gestational day (GD) 7 to 20. Daily maternal body weight, food, and water intake were measured. Blood pressure assessment and glucose tolerance test were done on GD20. Fetal plasma and placenta were collected on GD20 and processed for fatty acid measurement using LC-mass spectrometry. The expression of fatty acid metabolism-related genes in the placenta was assessed using RT2 Profiler PCR arrays. The results were validated by qRT-PCR. Blockade of insulin receptors with S961 in pregnant rats resulted in glucose intolerance with increased fasting glucose and insulin levels. Maternal body weight gain and food and water intake were not affected; however, S961 significantly increased maternal blood pressure and heart rate. The placenta n3 and n6 LCPUFA concentrations were significantly decreased by 8% and 11%, respectively, but their levels in the fetal plasma were increased by 15% and 4%. RT2 profiler arrays revealed that placental expressions of 10 genes related to fatty acid β-oxidation (Acaa1a, Acadm, Acot2, Acox2, Acsbg1, Acsl4, Acsm5, Cpt1b, Eci2, Ehhadh) and 3 genes related to fatty acid transport pathway (Fabp2, Fabp3, Slc27a3) were significantly upregulated. In summary, lack of insulin action increased the expression of genes related to placental fatty acid β-oxidation and transport with an increased transfer of LCPUFA to the fetus. The increased lipid levels routed toward the fetus may lead to fat adiposity and later-life metabolic dysfunction.

Diaper-zero program (prompted voiding care) improves diaper use in nursing home residents

With an aging population, the number of older adults admitted to nursing homes has increased. Diapers are often used to manage nursing home resident urinary incontinence, yet only one-third of these required assistance from caregivers to urinate. Unnecessary diaper use was reported in 23.9% of peop1e, mostly for precautionary purposes. In this study, the Diaper-zero program caregivers asked residents regularly (every 2-3 h) whether they required voiding and prompted them to void. Over 11 months, the effects on 38 nursing home residents' diaper use, nursing care level, physical activity, daily energy, and water intake were measured. A higher rate of diaper wearing was initially observed with lower daily energy and water intakes at the beginning of the Diaper-zero program, but this association was not observed after 11 months of the program. The diaper usage rate decreased significantly from 71.1% to 47.4% after 11 months. During this period, for all subjects, nursing care level, physical activity, and total daily intakes of energy and water were unchanged. In conclusion, this program enhances the desire to void, minimizing diaper usage, thus protecting the human dignity of nursing home residents. J. Med. Invest. 70 : 221-225, February, 2023.

Toxicological evaluation of aqueous leaf extract of Terminalia catappa linn (combretaceae) in pregnant rats.

Terminalia catappa (T. catappa) leaves are used in the treatment of hypertension, diabetes, cough, jaundice, indigestion etc, while the bark is used to treat diarrhea, dysentery, abscesses etc. Due to the acceptance and increased use of medicinal plants in pregnancy, there is a need to evaluate their toxicological profiles in pregnancy for safe use. This study aims to evaluate the toxicological effects of aqueous leaf extract of T. catappa in pregnant rats. acute toxicity study was carried out using Organization of Economic Corporation Development (OECD) 423 guidelines. Seventy-five rats (50 females and 25 males) were used at the age of 2 weeks just after weaning. The male rats were separated from the female rats in different cages and allowed to mature for 10 weeks. Then the rats were allowed to mate. After mating, 20 female rats with viable spermatozoa counts were selected and divided into 4 groups of 5 rats each (n=5). The control group received distilled water while the treatment groups II, III, and IV were administered with aqueous leaf extract of T. catappa orally at graded doses of 100, 200, and 400 mg/kg respectively for 21 consecutive days. The daily food and water intake, and weight were recorded. On the 22th day, the rats were anesthetized by chloroform inhalation, and blood samples were collected for haematological and biochemical analysis. The maternal livers, kidneys, and hearts were collected and weighed, and histological studies were carried out. The fetuses were removed and examined. An isolated tissue experiment was carried out on the myometrium of the pregnant rat uterus. The isometric reading of the uterine contractions was recorded. the oral LD50 was found to be ≤2000-5000 mg/kg. There was a significant (p<0.05) increase in the mean food intake at the 100, 200, and 400 mg/kg doses of the extract used on the 14th and 21st days when compared to the 7th day. The renal function test showed a significant (p<0.05) increase for chloride. The liver function test revealed that the extract at 100 mg/kg dose, significantly (p<0.05) increased only Alkaline Phosphatase (ALP) liver enzyme, while at 200 mg/kg dose, only AST liver enzyme was significantly (p<0.05) increased, while at 400 mg/kg dose, ALT, AST, ALP, and albumin increased significantly (p<0.05) when compared to the control group. There was a significant (p<0.05) decrease in the relative organ weight of the liver at 400 mg/kg dose of the extract. The liver histology showed moderate hepatic vacuolation and necrosis, while the histology of the kidney showed slight tubular necrosis. this study has shown that the aqueous leaf extract of T. catappa is relatively not safe in the pregnant rats. Although it is non-toxic to the fetus, it exhibited tocolytic effect by inhibiting uterine contractions, thus it should be used with caution during pregnancy, especially in the third trimester or during labor.

Gradient heating induced better balance among water transportation, salt resistance and heat supply in a high performance multi-functional solar-thermal desalination device.

Solar-driven desalination (SDD) is a promising technology for addressing water scarcity. However, how to overcome the trade-off between water transportation and heat supply of the evaporator to achieve a high evaporation rate and good salt tolerance simultaneously remains a challenge. Here, a novel all-in-one multi-functional SDD evaporator undergoing gradient heating is used. This evaporator incorporates a hydrophilic PDA (polydopamine)@CNT(carbon nanotube)/PVA (polyvinyl alcohol) aerogel with vertically aligned structures as the water evaporation layer, enabling rapid water transportation. Surrounding the evaporation layer, there is a photothermal hydrophobic CCP (cotton/CNT/polydimethylsiloxane) film that serves as the heating layer, enhancing the heat supply to the evaporation layer. This innovative design strikes a favorable balance between water transportation and heat supply, facilitating high evaporation rates and good salt tolerance simultaneously, while also maximizing electricity generation. Due to the wettability difference between the evaporation layer (PVA aerogel) and heating layer (CCP film), a record stable temperature gradient of nearly 70 °C was formed between the CCP film and the PVA aerogel under 1 sun irradiation, so that heat on the high-temperature CCP film was continuously transferred to the low-temperature aerogel through its thermal conductive network, leading to a high evaporation rate of 6.96 kg m-2 h-1 under 1 sun irradiation in 5.0 wt% sodium chloride (NaCl) brine (higher than the world average seawater salinity (3.5 wt%)). Meanwhile, high flux directional flow of brine generated 130 mV stable voltage and 120 μA circuit current. Furthermore, the evaporator illustrates good stability for consecutive 7 days of testing and shows industry-leading comprehensive performance of SDD in actual use. More importantly, it was tested in real Bohai seawater under weak natural light, and fresh water generated can meet the recommended daily intake of water for 2.6 households and the simultaneously generated voltage reaches above 60 mV. In addition, the evaporator exhibits good adsorption capacity for heavy metals and dye molecules. This simple and universal solar evaporation structure is suitable for the assembly of gradient thermal structures for most solar thermal materials reported in the literature, which provides a new route for maximizing the use of solar energy for freshwater and electricity generation.

ASSOCIATION BETWEEN WATER INTAKE AND ANTHROPOMETRIC MEASUREMENTS: A CROSS SECTIONAL STUDY AMONG A SAMPLE POPULATION OF PAKISTANI DENTAL STUDENTS

Background: Role of water is well known as an essential nutrient in human health. Lifestyle medicine researches have shown high prevalence of inadequate hydration habits globally. In this study, the relationship of daily water intake with anthropometric measurements in young adults of a particular geographical location were observed. Methods: This cross-sectional study was conducted on 259 undergraduate students of Islamic International Dental College (IIDC), from September 2021 to February 2022. To assess daily water intake, an online questionaire was filled, whereas anthropometric measurements were done according to the recommendations of the International Standards for Anthropometric Assessment. Associations of Body Mass Index (BMI) with Waist Circumference (WC), Waist/Hip Ratio (WHR), Abdominal Circumference (AC), and Daily Water Intake (DWI) were analyzed by multiple linear regression analysis. One-way ANOVA was also used to determine the relationship of DWI with BMI, WC, AC and WHR, and considered significant at p?0.05. Results: One-way ANOVA analysis showed statistically significant differences in the mean values of BMI (F=6.0, p=0.001) and WC (F=7.5, p&lt;0.001) and no significant difference was found in the mean value of WHR (F=2.0, p=0.10) between the different DWI groups. Post hoc Tukey’s test followed by ANOVA revealed that BMI, WC, and WHR were statistically lower among students having adequate daily water intake (21.0±3.8 Kg/m2, p=0.001; 79.2±9.7 Cm, p&lt;0.001; and 0.78±0.04, p=0.013 respectively). Conclusion: Significant association was found between adequate daily water intake and lower values of BMI, WC and WHR. Pak J Physiol 2022;18(4):14?7

Comparative Assessment of the Effects of Consumption of Ginger and Marijuana on Learning and Memory in Swiss Mice

A plethora of medicinal plants have been shown to improve memory, cognition, and intelligence. Zingiber officinale (Ginger) and Cannabis sativa (Marijuana) have been shown to affect memory, cognition, and intelligence too. This study aimed at comparing the effects of Zingiber officinale and Cannabis sativa on learning and memory was carried out in Swiss mice. The mice were randomly divided into 3 groups of 15 animals each. Group 1 (control) were fed mice feed. Group 2 (ginger group) were fed with a ginger-laced diet containing ginger and mice feed at a percentage ratio of 5:95. Group 3 (marijuana group) were fed with a marijuana-laced diet containing marijuana and mice feed at the percentage ratio of 5:95. All mice were fed for 14 days and given water to drink daily. Daily food and water intake were recorded. The mice were evaluated for learning and spatial memory using novel object recognition tests and data obtained were subjected to ANOVA and T test respectively. The result showed that the Zingiber officinale group showed significantly better memory as seen by an increase in the recognition index when compared to the other groups. This shows that Zingiber officinale shows positive effects on cognition than Cannabis sativa at the same dose.

Predictors of sugar-sweetened carbonated beverage consumption and its effect on adiposity parameters of female Saudi students.

The prevalence of obesity has recently increased, accompanied by a steep increase in the consumption of sugar-sweetened carbonated beverages (SSCBs). This cross-sectional study was conducted to evaluate the impact of SSCB consumption on adiposity parameters and to identify factors associated with increased SSCB intake among young adult females in Makkah, Saudi Arabia. A validated closed questionnaire including 2 sections, general socioeconomic and behavioral characteristics and anthropometric measurements, was used for data collection of female students (n = 1616) from Umm Al-Qura University, Makkah, Saudi Arabia. Furthermore, height, weight, body mass index (BMI), waist circumference (WC), hip circumference (HC), and body composition were measured using an Omron HBF-510 body composition analyzer. Overall, 30.2% of the study participants consumed soda regularly. However, the percentages of occasional and never/rare soda intake were 40.1% and 29.7%, respectively. The results showed that BMI, WC, HC, body fat, and visceral fat increased with increasing SSCB intake. Physical inactivity, low income, smoking, low daily water intake, and obesity were associated with increased consumption of SSCB. In conclusion, a high rate of SSCB consumption increased obesity and body fat content in young adult females in Makkah City. Physical inactivity, low income, smoking, low daily water intake, and obesity were identified as predictors of increased SSCB consumption. Specific health education programs and effective public awareness campaigns could be held to address unhealthy SSCB drinking patterns to help improve young women's health.

Personalized prediction of optimal water intake in adult population by blended use of machine learning and clinical data

Growing evidence suggests that sustained concentrated urine contributes to chronic metabolic and kidney diseases. Recent results indicate that a daily urinary concentration of 500 mOsm/kg reflects optimal hydration. This study aims at providing personalized advice for daily water intake considering personal intrinsic (age, sex, height, weight) and extrinsic (food and fluid intakes) characteristics to achieve a target urine osmolality (UOsm) of 500 mOsm/kg using machine learning and optimization algorithms. Data from clinical trials on hydration (four randomized and three non-randomized trials) were analyzed. Several machine learning methods were tested to predict UOsm. The predictive performance of the developed algorithm was evaluated against current dietary guidelines. Features linked to urine production and fluid consumption were listed among the most important features with relative importance values ranging from 0.10 to 0.95. XGBoost appeared the most performing approach (Mean Absolute Error (MAE) = 124.99) to predict UOsm. The developed algorithm exhibited the highest overall correct classification rate (85.5%) versus that of dietary guidelines (77.8%). This machine learning application provides personalized advice for daily water intake to achieve optimal hydration and may be considered as a primary prevention tool to counteract the increased incidence of chronic metabolic and kidney diseases.

A Vision-Based Cattle Recognition System Using TensorFlow for Livestock Water Intake Monitoring

This letter presents a new method for identifying individual cattle for the purpose of tracking and efficiently measuring their daily water intake using a vision-based machine learning system. In addition to the current solution of using radio frequency identification (RFID), the proposed system uses TensorFlow Object Detection to detect labels on the RFID tag. The proposed system can be integrated into the current water intake monitoring system and alleviates the errors introduced by the unreliable RFID readers. The system allows users to train an object recognition model that can recognize and differentiate the labels on the ear tags of individual farm animals, so the drinking events can be recorded by the water intake monitoring system. The models are trained using custom datasets of manually annotated tag images with pretrained model architectures from TensorFlow 2 Model Zoo. The system is tested using images from event-triggered weather-proof cameras deployed in the grazing site. Experimental results of the system showed an accuracy of around 90%. In comparison to other present methods, this newly proposed system provides scalability and flexibility, making it an attractive vision-based solution for machine learning systems in agriculture.

Behaviors of Water Intake, Hydration Status, and Related Hydration Biomarkers among Physically Active Male Young Adults in Beijing, China: A Cross-Sectional Study.

Studies on the water intake of athletes in daily life are insufficient. The objective was to determine the water intake and hydration status among physically active male young adults. In this cross-sectional studies study, 111 physically active male young adults were recruited. The amount of daily total drinking fluid intake (TDF) among participants was recorded and evaluated in real time over 7 days using the "7-day 24-hour fluid intake questionnaire" (liq. In 7). The daily water intake from food (WFF) was calculated using the weighing, duplicate portion, and direct-drying method over 3 days. All urine samples over 3 days were collected, and urine biomarkers were determined. According to 24 h urine osmolality, the participants were divided into three groups with euhydration status, middle hydration, and hypo hydration statuses. Finally, 109 participants completed the study. The median daily total water intake (TWI), TDF, and WFF were 2701, ik1789, and 955 mL, respectively. Among participants, 17 participants (16%) were in euhydration status, 47 participants (43%) were in hypohydration, and 45 participants (41%) were in middle hydration. There were statistical significances in the 24 h urine volume, osmolality, urine specific gravity, and concentrations of K, Na, and Cl in different hydration statuses (χ 2 = 28.212, P < 0.01; χ 2 = 91.341, P < 0.01; χ 2 = 47.721, P < 0.01; χ 2 = 41.548, P < 0.01; χ 2 = 46.863, P < 0.01; and χ 2 = 40.839, P < 0.01). Moderate-intensity correlations were found between the TDF and 24 h urine volume, 24 h urine osmolality, 24 h urine Na concentration, morning urine osmolality, and morning urine Na concentration (r = 0.408, P < 0.01; r = -0.378, P < 0.01; r = -0.325, P < 0.01; r = -0.344, P < 0.01; and r = -0.329, P < 0.01). There were also moderate-intensity correlations between the TDF and 24 h urine osmolality, morning urine osmolality, and morning urine Na concentration (r = -0.365, P < 0.01; r = -0.371, P < 0.01; and r = -0.322, P = 0.01). Increased and higher moderate-intensity correlations were found between plain water and 24 h urine volume, 24 h urine osmolality, 24 h urine K and Na concentration, morning urine osmolality, and morning urine Na concentration (r = 0.374, P < 0.01; r = -0.520, P < 0.01; r = -0.312,P < 0.01; r = -0.355, P < 0.01; r = -0.446, P < 0.01; and r = -0.378, P < 0.01). Insufficient water intake and hypohydration were common among physically active male young adults. The amount and type of water intake were correlated with hydration status and urine biomarkers. The results could provide scientific and accurate references for the development of recommendations on water intake for athletes.

Effect of daily water intake on the level of anxiety among medical students of Khawaja Muhammad Safdar Medical College, Sialkot

&lt;p&gt;&lt;strong&gt;Background and Objective:&lt;/strong&gt; A high incidence of burnout, depression, and anxiety is found among medical undergraduate and postgraduate students worldwide with the increasing prevalence of stress. The objective of this study was to analyze the correlation between water intake and the risk of anxiety among medical undergraduates of a public sector medical college in Pakistan.&lt;br /&gt;&lt;strong&gt;Method:&lt;/strong&gt; This cross-sectional study was conducted on 375 medical undergraduates of Khawaja Muhammad Safdar Medical College, Sialkot, Pakistan. To assess the level of anxiety, the Generalized Anxiety Disorder Assessment Scale 7 (GAD-7) was used. Points 3-0 were assigned to response categories of &amp;ldquo;nearly every day,&amp;rdquo; &amp;ldquo;more than half the days,&amp;rdquo; &amp;ldquo;several days,&amp;rdquo; and &amp;ldquo;not at all,&amp;rdquo; respectively. GAD-7 score was calculated by adding together the scores for seven questions. Scores of 15, 10, and 5 were taken as cut-off points for severe, moderate, and mild anxiety, respectively. Calculation of water consumption was carried out based on the number of water glasses intake per day. It was classified into &amp;lt;4, 4-7, and &amp;gt;7 of water/day.&lt;br /&gt;&lt;strong&gt;Result:&lt;/strong&gt; Out of 110 male medical students, 58.2% were suffering from normal to mild anxiety and 41.8% from moderate to severe anxiety. A total of 40.0% and 60.0% of female medical students were suffering from normal-mild and moderate-severe anxiety, respectively. The risk of anxiety was more among female than male students. Logistic regression indicated a correlation between decreased anxiety and female gender and water intake of 4-7 or &amp;gt;7 glasses/day.&lt;br /&gt;&lt;strong&gt;Conclusion:&lt;/strong&gt; The findings of the current study showed lesser anxiety levels in male students and an inverse relationship between water intake and level of anxiety. Therefore, increasing the intake of water can be beneficial in reducing stress and anxiety thus improving the quality of life.&lt;/p&gt;

PSXVI-3 Individual Water Use Efficiency in Beef Cattle

Abstract Public opinion has focused on animal agriculture being in competition with growing urban populations for land and water resources. With much of the US in drought conditions, improving water use efficiency is critical for the sustainability of animal agriculture. To date, little has been done to assess water efficiency in cattle. There is evidence for a positive relationship between water intake and DMI, but relationships between water and feed use efficiencies are likely more complex. Our objectives were to understand the magnitude of variation in water use efficiency and make comparisons with feed efficiency, as measured by residual feed intake (RFI). Our study utilized yearling bulls, steers, and heifers (n=745) between the summer of 2019 and the summer of 2021. Individual feed and water intakes were determined using a real-time feed intake system and an In Pen Weighing system (IPW). Water use efficiency, residual water intake (RWI), was calculated similarly to RFI where an expected water intake was determined for the group by regressing average daily water intake on metabolic mid-body test weight and either ADG or DMI. RWI was then calculated as actual daily water intake minus expected daily water intake. The estimation of expected water intake using DMI had a greater R2 than when ADG was used (.36-.51 vs .31-.35). The range in off-test RFI was about one order of magnitude smaller than the range of RWI (e.g., RFI -0.90 to 0.73 kg vs RWI -7.34 to 8.49 L), indicating greater variability in water intake compared with feed intake and a relationship among DMI, ADG, and RWI that needs to be further explored. As animal agriculture strives to be more sustainable, water use efficiency needs to become a common measure and genetic progress needs to be made. There appears to be sufficient variation in the trait to make this feasible.

Consumption, productivity and cost: Three dimensions of water and their relationship with the supply of artificial shading for beef cattle in feedlots

It is important to understand the relationship between beef cattle water performance and animal welfare. However, to date, there is no knowledge of studies carried out to assess the water productivity of cattle when using an animal welfare practice. This study aimed to evaluate the impact of artificial shading in the water intake and water productivity and the relationships between these indicators with animal performance and water cost in a cattle feedlot system. Animals were divided into two groups, with shade (GS) and without shade (GWS), and they were housed in four collective pens. Water intake (WI, L day−1), dry matter intake (DMI, kg day−1), and average daily gain (ADG, kg day−1) were obtained for all cattle individually. To calculate water productivity, water input was the direct technical water represented by animal drinking. The average daily water intake for animals under shade was 36.8 L day-1. Animals without shade consumed 9% (3.3 L day−1) more water than animals under shade. Animals under shade presented higher water productivities. The average water productivity per kilograms of live weight of animals under shade was 0.203 kg LW L−1 water, with a maximum of 0.264 kg LW L−1 water and a minimum of 0.159 kg LW L−1 water. These values were 0.185, 0.234, and 0.097 kg LW L−1 water, respectively, for animals without shade. This is justified due to the lower average water intake for these animals and due to the numerically higher live weight and carcass weights. The results showed that if a production system uses shade in the feedlot, the water payment could be reduced by 7.2%. The study demonstrated that animals had a benefit by being produced with better welfare, the environment has a benefit by producing the same output with less water input, and the consumer wins by having an available product with environmental and animal welfare values.

Health-related behaviors of undergraduate medical students of public sector university, Karachi 2022

Objective: to study health-related behaviours of undergraduate medical students of the public sector university of Karachi by analyzing the following aspects : 1. Daily water intake and its importance. 2. Refractive errors and the importance of their correction 3. Sun protection. Study Design: Cross-sectional randomized study Methodology: From April 2022 to June 2022, a cross-sectional study was conducted at Jinnah Sindh Medical University considering all ethical values. A sample size of 316, was calculated with an open epi calculator. We collected data through online Google forms and hard copies. SPSS 22 was utilized for data analysis, where the confidence interval was 95% with an error margin of 5%, and a 0.05 p-value. Results: Daily Water Intake: 63.9% of participants marked the correct daily water requirement which is 2 liters (8 glasses). Only 50.3% of pupils fall under the category that were consuming the standard daily water intake. The mostdifficult part of fulfilling the daily water requirement was that they could not remember drinking water. Refractive errors and the importance of their correction: 94.6% of participants wore spectacles for far vision, highlighting the prevalence of myopia. 81% of pupils had a range of refractive errors between 1-5, reflecting that error ranges are not high. A positive response was recorded busting the myth that spectacles weaken the eyesight when 70.6% of people negated it. Sun protection: 62.3% of pupils considered UV light harmful. 54.4% stated that their outdoor hours were from 2 to 4 hours. When asked if they check the UV light index before spending a long day outdoors, 78.5% said no. The application of sunscreen when going out was acknowledged by 61.7%. 90.2% responded that they agree to the fact that sunscreens are effective against sun protection. Conclusion: With an aspiration to become a nobilityamongst doctors, medical students must recognize their responsibility in being the representatives of right and wrong. Thus, the participation of the students in this study provides valuable insight into their health related behaviors portrayed against the risks of sun exposure and the benefits of using sunscreen as a protective measure, along with corrective measures chosen against poor sight such as spectacles, and determining the daily water requirements and their benefits. Findings in this study portray that although it is reassuring that a majority of the medical students know the harmful effects of prolonged sun exposure, a lot still needs to be done on the part of our future doctors in the effective method of application of sunscreens. This study has also shown a generally correct direction towards early treatment and whether wearing spectacles continuously further deteriorates sight. However, there is a considerable notion of dependency upon a certain apparatus ergo a dependent lifestylecomprising issues such as lowered confidence and negative affect on wedding proposals. Further studies should be done with focus on the society’s role in adhering to early wearing of spectacles and the issues associated with the habit of wearing them such as rashes, nose spots, headaches and dark circles. This study has also made it significantly apparent that the majority of the medical students still do not have the correct knowledge regarding daily water requirements and their benefits, which needs to be addressed. This will help them learn better habits about drinking water that will benefit their personal and academic lives. They will be able to treat their patients with the correct information as well. Keywords: health behaviors, medical students, water intake, refractive errors, sun protection.

Water Intake and Organ Weights of Red Sokoto Goats Fed Different Forms of Neem Leaves, Supplemented with a Concentrate Diet

The study evaluated the water intake and organ weights of red sokoto goats fed different forms of neem (Azadirachta indica) leaves and concentrate diet. The experiment was carried out at the smal ruminant unit Teaching and Research Farm, Federal University of Kashere. Sixteen red sokoto goats (bucks) aged between 7 to 9 months with a weight range of 6.8 kg to 7.3 kg were allotted into four (4) treatments of four goats each. The goats were housed individually in pens. The goats were fed fresh neem leaves, neem leaves hay, neem leaves meal and neem leaves silage at 300g/goat/day for treatments 1, 2, 3 and 4 respectively; and concentrate diet at 125g/goat/day for a duration of sixty- three (63) days. Known volume of water was served and daily water intake was determined. The experimental design was a completely randomized design; data were analyzed using a one- way analysis of variance. The significant means were separated using Least Significant Difference contained in SAS 9.4 statistical packages, 2018 edition. The concentrate and the neem leaves were analyzed for their proximate composition using the method of AOAC (2000). The daily water intake values ranged from 286.87 – 392.95 ml and were significantly (P&lt;0.05) different across the treatment means (significant between which Treatment 1 on one hand and Treatments 2, 3 and 4 on the other hand and both values increased with dry matter intake. All the organ weights values evaluated were not significantly(P&gt;0.05) different across the treatment means. and which value, water intake/dry matter intake (2.70 – 3.87ml/g) values also showed significant (P&lt;0.05 difference between The values for kidney ranged from 0.50 – 0.53 % while those for liver were 2.10 – 2.17 % It was concluded that the various forms of the neem leaves had no influence on the water intake of the goats, the different forms of neem leaves were not toxic to the goats afe he goats. Neem leaves can be used to feed goats during the long dry season. Further research should be carried out using other species of ruminants such as sheep and cattle.

Рекреаційно-оздоровча діяльність жінок з використанням засобів реабілітаційного фітнесу

The purpose of the study is to examine the impact of rehabilitation fitness on the physical condition of women with musculoskeletal disorders. Materials and methods. The study was held on the basis of the fitness club "LIGA" in Lviv and was attended by 65 women of the first mature age with musculoskeletal disorders. The methods used were: theoretical analysis and generalization of data from scientific and methodological literature; pedagogical observation; sociological method; pedagogical testing; pedagogical experiment; medical and biological methods; methods of mathematical statistics. Results and discussion. As the survey showed female fitness club visitors pay attention to the study of various aspects of leading a healthy lifestyle. The main sources of informing women about the need for health-improving classes for most women (47.2%) were friends and 27.0% of people received information from the Internet. Strength fitness is preferred by 62.0% of people. 22.3% of women preferred cyclic kinds of physical activities. Dance fitness programs attract 8.9% of respondents. Further research was aimed at studying the impact of rehabilitative fitness classes on women's health. 21 women who had osteochondrosis and consented to participate in the study were involved in the pedagogical experiment. The program of rehabilitation fitness classes was developed taking into account the recommendations of specialists and was aimed at restoring the functional state of the spine and preventing recurrence of the disease. In addition, women were offered individual recommendations for daily water intake, a balanced diet and daily routine. Conclusion. It was found that 68.8% of women surveyed are interested both in information about general health and health promotion and leisure activities; 22.6% of women are interested in the features of certain types of health activities; 12.9% of people would like to learn about the possibilities of non-traditional remedies and 1.1% are not interested in healthy living. It is determined that after the use of rehabilitation fitness classes the number of persons with below average level decreased by 19.1%; the number of women with an average level of physical condition increased by 23.8% and the number of persons with above-average level increased by 4.8%. However, women with low and high level of physical condition were not detected. It was found that the percentage of fat in women before the pedagogical experiment was 22.98 ± 6.37%, while after three months of training its rate was 20.24 ± 5.79%. There was an improvement of this indicator by 11.9%. In terms of weight, it decreased by 2.13 kg

Health Risk Analysis of Detergent Contamination in Communities on Kodingareng Lompo Island, Makassar City

Domestic activities in coastal and island communities are one of the factors that can affect the quality and quantity of traditional well water availability. One of the parameters of household wastewater is detergent pollutants. This study aimed to analyze the risk of detergent contamination in drinking water in the community of Kodingareng Lompo Island. This research is a type of quantitative research with a descriptive approach. The method used is the Environmental Health Risk Assessment (EHRA) approach. Based on the examination conducted, the highest concentration was found in drinking water samples 4 and 5, which was equal to 2.98 mg/l. While drinking water sample 2 has the lowest concentration of detergent contamination, which is 0.005 mg/l. The respondents' daily drinking water intake rate is &lt; 2 L/day, 2 L/day and ≥ 2 L/day, with the highest percentage of 31.1% for consumption of 2 L/day. The frequency of detergent exposure in drinking water consumed by respondents, namely &gt; 350 days/year, with a percentage of 84.4%. The most extended duration of exposure, namely 31 - 60 years, with a ratio of 64.4%. The results of ARKL calculations conducted on the concentration of detergent contamination in drinking water showed a high level of risk (RQ &gt; 1) in three respondents and were classified as unsafe for drinking water consumption.

Assessment of water consumption during Ramadan intermittent fasting: Result from Indonesian cross-sectional study.

During Ramadan fasting, people are likely to consume water and beverages lower than recommended intake due to the limited time. However, it is necessary to achieve the recommended daily water intake to maintain the hydration status, as well as productivity during fasting. Unfortunately, there is a lack of data on drinking patterns during Ramadan. This study aims to investigate water and beverage intake and drinking patterns to help achieve water requirements during Ramadan among Indonesian adults. This is a cross-sectional study conducted during the Ramadan period from April to May 2021 (Ramadan 1442 Hijri). We used a self-administered questionnaire on drinking habits during Ramadan and utilized a 7-day fluid record (Liq.In 7) to assess water and beverage intake among participants who were managed through online procedure. There were 380 participants from five universities across Indonesia who completed the questionnaire accordingly and then analyzed it. The result shows that total water and beverage intake during Ramadan among participants was below the recommendation [1,670 (1,326–2,034) ml/day]. Among the type of beverages, water is the highest level of consumption [1,262 (983–1,666) ml/day] then followed by sugar-sweetened beverages [200 (91–350) ml/day]. We found a significant difference in water and beverages consumption between time of iftar [474 (375–590) ml/day], nighttime [574 (414–810) ml/day], and suhoor [560 (423–711) ml/day]. From this study, we found that during Ramadan the most common drinking pattern is 2-4-2, but a drinking pattern of 4-2-2 glasses (sequence of four glasses at iftar, two glasses at nighttime, two glasses at suhoor) had a significantly higher chance to adhere with the recommendation of fluid intake compared to other patterns. Therefore, based on this research on water and beverage intake, it is necessary and important to make improvements among Indonesian adults during Ramadan, and the drinking pattern of 4-2-2 glasses may help to achieve the recommended daily water consumption.

Personalized optimal nutrition lifestyle for self obesity management using metaalgorithms

Precision medicine applies machine learning methods to estimate the personalized optimal treatment decision based on individual information, such as genetic data and medical history. The main purpose of self obesity management is to develop a personalized optimal life plan that is easy to implement and adhere to, thereby reducing the incidence of obesity and obesity-related diseases. The methodology comprises three components. First, we apply catboost, random forest and lasso covariance test to evaluate the importance of individual features in forecasting body mass index. Second, we apply metaalgorithms to estimate the personalized optimal decision on alcohol, vegetable, high caloric food and daily water intake respectively for each individual. Third, we propose new metaalgorithms named SX and SXwint learners to compute the personalized optimal decision and compare their performances with other prevailing metalearners. We find that people who receive individualized optimal treatment options not only have lower obesity levels than others, but also have lower obesity levels than those who receive ’one-for-all’ treatment options. In conclusion, all metaalgorithms are effective at estimating the personalized optimal decision, where SXwint learner shows the best performance on daily water intake.

Comparative Effects of Cashew Nut, Leaf and Stem Bark (Anacardium Occidentale L.) on Hyperglycemia and Associated Abnormalities in Streptozotocin-Induced Diabetic Rats

Background: Medicinal plants are used as alternative therapy for diabetes. This study investigated comparative effects of methanolic extracts of Anacardium occidentale (linn) nut, leaf and stem bark on hyperglycemia and associated abnormalities in streptozotocin-induced diabetic rats.&#x0D; Methods: Ninety male Wistar albino rats weighing (200±20g) were used and diabetes was induced by single intraperitoneal injection of streptozotocin (50mg/kgb.wt). The rats were allotted into 9 groups, 10rats/group. Group I: (non-diabetic); Group II: (diabetic untreated); Groups: III &amp; IV: diabetic rats received 100mg/kgb.wt&amp; 200mg/kgb.wt nut extract; Groups: V &amp; VI: diabetic rats received 100mg/kgb.wt&amp; 200mg/kgb.wt leaves extract; VII &amp; VIII were diabetic rats received 100mg/kgb.wt&amp; 200mg/kgb.wt stem bark extract and Group IX: diabetic rats received 2mg/kgb.wt p.o glimepirides for 4weeks. Daily food and water intakes were recorded; weekly body weight and blood glucose levels were measured throughout the experiment. The animals were sacrificed on the last day and fasting plasma blood glucose was withdrawn for biochemical parameters estimation.&#x0D; Results: Fasting plasma blood glucose, triglyceride (TG), total cholesterol (TC), low density lipoprotein-cholesterol (LDL-C), aspartate aminotransferase (AST), alanine aminotransferase, alkaline (ALT), aminotransferase (ALP), urea, uric acid, creatinine, malondialdehydes (MDA) and water intake levels were significantly (p&lt;0.01, 0.05) reduced in the extracts treated groups. However, High density lipoprotein- cholesterol (HDL-C), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), reduced glutathione (GSH), body weight and food intake levels were significantly (p&lt;0.01, 0.05) increased in the extracts treated groups.&#x0D; Conclusion: Anacardium occidentale parts posses anti-diabetic properties. The nut has extreme therapeutic efficacy and could be used as alternative therapy for diabetes.&#x0D; Keywords: Anacardium occidentale, Hyperglycemia, Lipid profiles, Antioxidants, Kidney function.