Objective: Real-time monitoring of glucose by CGM is a validated tool in the management of diabetes, but its use in CF-related diabetes (CFRD) is new and the attitudes of CF patients towards it are unknown. To assess this further, we surveyed our adult CF patients who had undergone CGM as part of the management of their CFRD. Method: Thirty patients (20 female) completed a 5-point Likert questionnaire. Results: Most (83%) found the device easy to use and the instructions clear, and 77% indicated that CGM did not affect their daily routine, but in the remainder it interfered with sleep (50%), washing activities (42%), and choice of clothing (38%). Side-effects were reported by only 27%: of these, 57% noted pain and 43% a skin reaction − 1 patient found these unacceptable. The majority stated they did not modify their diet (86%) or exercise regimen (90%) during the test. Two thirds also performed blood glucose monitoring during the duration of CGM as instructed, with 68% reporting a good correlation with the CGM results. Following this test, 73% reported a better understanding of blood glucose levels, 47% of insulin management and 77% of the relationship between dietary intake and blood glucose levels. Subsequently, 33% have modified their diet, and 90% would undergo CGM in future if required. Conclusions: Although intrusive, CGM is perceived by patients as a useful and acceptable tool for the monitoring of their CFRD, with a low side-effect profile. We encourage other CF units to consider its use for the management of this increasingly common adult CF complication.