Cyclone Separator Research Articles

Plasma metabolomics for diagnostic biomarkers on ectopic pregnancy

Metabolomics is a relatively novel omics tool to provide potential biomarkers for early diagnosis of the diseases and to insight the pathophysiology not having discussed ever before. In the present study, an ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS) was employed to the plasma samples of Group T1: Patients with ectopic pregnancy diagnosed using ultrasound, and followed-up with beta-hCG level (n = 40), Group T2: Patients with ectopic pregnancy diagnosed using ultrasound, underwent surgical treatment and confirmed using histopathology (n = 40), Group P: Healthy pregnant women (n = 40) in the first prenatal visit of pregnancy, Group C: Healthy volunteers (n = 40) scheduling a routine gynecological examination. Metabolite extraction was performed using 3 kDa pores - Amicon® Ultra 0.5 mL Centrifugal Filters. A gradient elution program (mobile phase composition was water and acetonitrile consisting of 0.1% formic acid) was applied using a C18 column (Agilent Zorbax 1.8 μM, 100 x 2.1 mm). Total analysis time was 25 min when the flow rate was 0.2 mL/min. The raw data was processed through XCMS – R program language edition where the optimum parameters detected using Isotopologue Parameter Optimization (IPO). The potential metabolites were identified using MetaboAnalyst 5.0 and finally 27 metabolites were evaluated to be proposed as potential biomarkers to be used for the diagnosis of ectopic pregnancy.

Numerical simulation of the complex flow field in a new recycling cyclone separator

Abstract The three-dimension flow field is simulated in a recycling cyclone separator using the Reynolds stress model (RSM) with Fluent 6.2. The results show that the unique design of the flow route of the recycling cyclone separator can improve the axial symmetry and the order of the inner flow field. The appearance of the eddy flow and the pressure drop of the recycling cyclone separator are also reduced. Moreover, the secondary circulation in the recycling cyclone separator is analyzed, which is useful for understanding the flow mechanism. This study provides a reference for further improvement of the recycling cyclone separator.

Numerical Performance Investigation of a Side‐outlet Cyclone for Particulate Matter and Polymer Powder Separation

AbstractThe side‐outlet cyclone, featuring a novel geometric design with a lateral gas outlet, proves advantageous in space‐constrained environments compared to traditional cyclones with top gas outlets. Herein, a cyclone separator with a side‐outlet configuration was numerically investigated using the renormalization group k‐ε model and pressure drop and separation efficiency as the performance parameters. Simulation results revealed that the side‐outlet cyclone operates at a low to moderate pressure drop of 80.8412 Pa, with a removal efficiency of 45.48 %. The operating pressure drop was found to be only one‐third of the computed pressure drop from mathematical modeling, with a removal efficiency 15 % lower than the experimental value. With varying cyclone design modifications, suitable experimental procedures and measuring approaches are desirable to further accurately corroborate these results.

Numerical simulation of gas-solid flow in a cyclone separator with additional inlet

In this study, an additional inlet was added to the gas-solid cyclone separator to enhance the separation efficiency. Four different heights were tested, including 0.95D, 1.4D, 1.5D, and 1.95D (D is the diameter of the cylindrical section). The investigation involved two inlet flow conditions: increasing and dividing the inlet flow rate. The finite volume method and Reynolds stress turbulence model were used to solve the averaged Navier–Stokes equations, whereas the Eulerian–Lagrangian approach and discrete phase model (DPM) were applied to track particles with a uniform diameter of 0.5–1.8 microns as the discrete phase. Owing to the low Stokes number and small and low-volume-fraction particles, a one-way coupling method was employed between air and the particles. The addition of an additional inlet reduced the static pressure in the center and downstream areas and increased the reverse flow velocity at the end of the cyclone. The installation of an additional inlet at 0.95D had the most positive effect on the separation efficiency, with an increase of 28.8% in the increasing flow rate case and 19.6% in the dividing flow rate case compared with the cyclone without an additional inlet. Furthermore, the increase in the separation efficiency of the submicron particles was greater than that of the larger particles in both flow distribution cases.

Analysis of the Influence of Gas Leakage in The Dipleg of Cyclone Separators on Particle Properties

The FCC unit uses a cyclone separator for gas-solid separation of catalysts from flue gas or oil and gas. When the cyclone separator experiences a gas leakage fault, it directly affects its separation performance, causing excessive catalyst emissions and leading to the occurrence of catalyst running faults. However, there is currently a lack of diagnostic technology for cyclone separator equipment malfunction and gas leakage. Therefore, the influence of the dipleg of the cyclone separator on the particle loss rate under different gas leakage velocities was investigated experimentally. Experiments show that under normal conditions, particles are subject to multiple cycle separation, and fewer particles randomly enter the riser with the upward rotating flow to escape, which is mainly determined by the structure size and inlet velocity of the cyclone separator. When gas leakage occurs in the dipleg, the higher the gas leakage velocity, the higher the particle loss rate. As the number of particle cycles increases, the loss rate gradually decreases. For this purpose, the cyclone separator inside the FCC unit in the industrial site is taken as the object. In response to multiple cyclone separator loss faults, the changes in process parameters and collected catalyst particle properties of the cyclone separator are analyzed, and the changes in the running dose inside the device during operation are analyzed. Based on the analysis results, the operation of the unit is optimized and adjusted to avoid unplanned shutdown and maintenance. Therefore, based on this, a fault diagnosis technology for catalyst loss in FCC unit cyclone separators based on particle property parameters has been created, which has the characteristics of accuracy and reliability and can be applied to the analysis and diagnosis of catalyst loss faults in FCC unit.

Experimental study on flow characteristics of ash band in a cyclone separator using HPIV techniques

In a reversed cyclone separator, the ash bands were frequently observed on the wall surface, which were formed by the separated particles and rotated down. Nevertheless, the flow characteristics of the ash bands are rarely measured and discussed in the previous literatures. In this study, the flow characteristics of the ash bands were experimentally investigated by use of the High-speed Particle Image Velocimetry (HPIV) method. The experiments were conducted on a ϕ160mm cyclone at inlet velocity of 12, 16, 20 m/s and inlet concentration of 30, 50, 70, 100 g/m3. The test powders were catalyst and iron powder. The ash band's geometric characteristics, including width, slope angle and pitch, were extracted through advanced image analysis algorithms. Results revealed that the slope angle and pitch of the ash band were different in the cylindrical section and cone section. The width decreased as the ash band moved downwardly. Additionally, the ash band's flow parameters were measured. As the particle movement changed from suspension pattern in the separation space to sliding pattern on the wall surface along the radial, the particle velocities decreased. And the particle velocities further decreased as ash band forming. Particle velocities exhibited non-uniform and fluctuating behavior within the ash band. Notably, the velocities were lower in the central region of the ash band than that at the outer layer. Meanwhile, the particle concentration gradually increased, leading to a particle concentration in the ash band being 450 times higher than the inlet concentration. Along the axial, the ash band averaged velocity initially increased in the cylindrical section and then decreased in the cone section, varied with the inlet velocity, inlet concentration and particle properties such as particle size and density. This study revealed mechanisms behind particle aggregation in cyclone separator and analyzed the dynamic flow characteristics of ash band in detail.

Wear and corrosion properties of HVOF sprayed WC-Cr3C2 composite coating for application in polysilicon cyclone separator

The wear and corrosion properties of the cyclone separator play a crucial role for the preparation of high-purity trichlorosilane in the Siemens method polysilicon cold hydrogenation system. In this work, we used fluent simulation technology to determine the optimal spraying process parameters of high velocity oxy-fuel (HVOF) technology, and the Ni60-WC composite coatings with different content of Cr3C2 were prepared on 316L stainless steel surface by using HVOF technology. The microstructure, phase structure and mechanical properties of the coating were characterized, and the wear resistance and corrosion resistance of the coating were studied. By comparing the friction coefficient, wear rate, wear profile and electrochemical polarization and impedance spectrum of the coating, the effects of Cr3C2 content on the microstructure, hardness, wear resistance and corrosion resistance of HVOF sprayed WC composite coating were studied. The results show that the coating prepared by using the simulation parameters are uniform and compact, the coating is tightly bonded to the substrate. The main phases in the coating are WC, W2C and Cr3C2. With the increase of Cr3C2 hard phase, the wear resistance and corrosion resistance gradually improve. Ni60–35WC–20Cr3C2 and Ni60–35WC–30Cr3C2 volume loss rate is the lowest, the friction depth is the shiniest, compared with the substrate, the wear rate is reduced by more than 95 %. Ni60–35WC–20Cr3C2 has the highest corrosion potential, the smallest corrosion current, the smallest corrosion rate and the largest impedance spectrum radius. However, when the content of Cr3C2 reaches 30 %, the corrosion resistance is the worst. Combined with wear resistance and corrosion resistance analysis, the Ni60–35WC–20Cr3C2 coating is selected to provide support for upgrading and prolongating the service life of the cyclone separator.

Numerical Investigation of Cyclone Separators: Physical Mechanisms and Theoretical Algorithms

AbstractGas‐particle aero‐type cyclones have revolutionized biochemical processes, engineering industries, and environmental pollution protection by effectively separating particles from gas. These devices rely on gravitational energy and centrifugal force to dissipate particle phase energy, but achieving optimal energy efficiency while minimizing pressure drop remains challenging. This has led to the development of various cyclone designs in commercial industries, each with unique energy efficiency characteristics. The intricate gas‐particle flow inside cyclones is a critical issue impacted by cyclone geometry, operating conditions, and media parameters. Advanced numerical simulations have been employed to understand this complex flow pattern better, offering researchers valuable insights into the mechanisms of different cyclone separators. This comprehensive review explores the available numerical methods in the literature on cyclones and their corresponding validations. Computational numerical modeling is a promising technique for predicting cyclone energy efficiency, gas‐particle behavior, and overall performance. This investigation delves into the progress and numerical forms of gas‐particle flow cyclones, examining how different parameters impact cyclone performance and flow patterns within the two‐phase flow. The future developments and challenges that may further promote the development of aero‐type cyclone separators, providing theory and engineering support for future cyclone designs, are also covered. As a result, it can confidently be reported that aero‐type cyclone separators remain a critical component in various industrial sectors, offering energy‐efficient solutions for mitigating environmental pollutants and gas‐particle separation systems. With continued development and research, these devices will undoubtedly shape the future of energy processes and engineering industries, ushering in a new era of sustainability and efficiency.

Performance analysis of multi-inlet cyclone separators considering different shapes and locations of the inlet ducts

The present study analyzes the performance of multi-inlet cyclone separators with different shapes and axial locations of the inlet ducts. The cyclone model having a single inlet has been considered as the reference model. The two inlets are incorporated such that the total cross-sectional area equals the original (single inlet) section – this ensures no change in the inlet velocity. Three cases for the shape of the cross-section have been considered. In the RA variant, the two inlet areas have been halved ensuring the same aspect ratio. In the RH variant, the height of the two inlets is half of the original duct. In the last case of the RW variant, the width of the two inlets is reduced by half of the original area. The impact of relative axial displacement between the two inlets is also analyzed. The advanced closure LES has been used to investigate the flow field as well as the performance. Conclusive results indicate that both pressure losses and collection efficiencies are the lowest in the RH variant and the highest in the RW variant. Furthermore, using continuous wavelet transformation, it has been revealed that the precessing frequency of the vortex core is time-dependent.

Detection of Excipient–Excipient Interaction in Dry Powder Inhaler Formulation Prepared by Spray Drying

Background: Dry powder inhalers (DPIs) are dosage forms that are used via the pulmonary route. Their formulations include two major parts; drug substance and carrier. For many years, DPIs have been made with lactose, a particularly popular carrier. Leucine has drawn more attention in recent years when it comes to DPI formulations made using the spray drying technique. Leucine was utilized in conjunction with carriers like lactose to enhance physicochemical and aerosolization properties. Method: In this investigation, when lactose and leucine were co-spray dried, the color of powders around the cyclone separators of the spray dryer turned brown while the produced powder in the collector was white. Both the white powder inside the collector and the brown powder around the cyclone separators were investigated by differential scanning calorimetry (DSC), Fourier transform-infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), x-ray diffraction (XRD), and liquid chromatography with tandem mass spectrometry (LC-MS-MS) to determine the identity of the degraded chemicals and to look for any potential interactions. Results: A new peak at 177 ºC in DSC analysis is a sign of interaction. Also, FT-IR analysis shows the new peak at 1627 cm-1 which is related to the carbonyl group. According to SEM and XRD analysis co spray dried leucine-lactose is amorphous. Obtained data from LC-MS analysis indicates the adduct compound of leucine-lactose that resulted from the Maillard reaction was detected in both white and brown powder. Also, the reaction proceeded to form n-formyl compound. Conclusion: There is a possibility of lactose and leucine incompatibility during DPIs manufacturing, especially in elevated temperature and humidity.

Research on structural parameter optimization of a new axial inlet hydrocyclone separator based on response surface optimization method.

Aiming at the problem that the current hydrocyclone separator is affected by multiple structural parameters and there is interaction between the multiple structural parameters, it is difficult to determine the optimal structure. Taking the new axial inlet hydrocyclone separator as the research object, a fast parametric optimization method based on response surface optimization method is proposed. The overflow outlet diameter, overflow tube depth and small cone length, which have significant influence on the separation efficiency of the axial inlet hydrocyclone separator, are selected as the optimal variables, and the cyclone separation efficiency is selected as the response index. A mathematical driving model between the response index and the optimal variables is constructed by using the second-order polynomial basis function. The optimal structural parameters of the new axial inlet hydrocyclone separator are obtained through the response optimization of the parameter variables in the global response range through the mathematical driving model, and the numerical simulation method and laboratory test are double verified. The results demonstrated that the axial inlet hydrocyclone achieved the highest separation efficiency within the studied operational parameter range when the overflow pipe diameter was 6mm, the overflow pipe depth was 20mm, and the small cone length was 60mm. The separation efficiency improved from 89% to 93%. The rapid optimization of the structural parameters of the axial inlet hydrocyclone was successfully accomplished using the response surface optimization method.

Experimental Analysis of Diesel Engine Performance and Emissions with the Integration of Cyclonic Separator Device

The high population density and demographic dynamics have triggered a boom in the uptake of larger and more fuel-efficient diesel goods vehicles because diesel is cheaper than gasoline. Nevertheless, availability of diesel engines has lead to an increase of pollution especially in the urban area. This research examines whether a cyclonic separator which is an attachment device mounted on the vehicle exhaust system can sufficiently reduce particulate emissions from diesel engines. Thanks, the cyclonic separator is used to gather particles of size from 1μm to 50μm, to control the emission of diesel exhaust pollutants. Although we find that the utilization of the device decreases the pollution emission, our study shows that the installation of the device causes backpressure leading to a marginal reduction in thermal efficiency of between 0.8% to 1.01%. Nevertheless, the cyclonic separator can be considered one of the possible means to solve the problem of reduction of emissions of diesel engines and protect urban environment from pollution.

Effect of internally mounted helical fins on the separation performance of a cylindrical gas-solid cyclone separator

In this study, an innovation was made by adding helical fins on the vortex finder of a cylindrical gas-solid cyclone separator, and the effect of this structural improvement on the separation performance was analyzed based on the flow field characteristics. The results show that both cyclones with and without helical fins exhibit a separation efficiency of almost 100% for particles larger than 5 ?m. As the inlet velocity increases, the effect of adding helical fins on the overall separation efficiency decreases, with a relative deviation of only 0.16% at an inlet velocity of 27 m/s, while it becomes increasingly effective in reducing energy consumption, with a pressure drop of 25.33%. The mechanism of the overall performance improvement lies in the fact that the helical fins change the flow field distribution in the cyclone, where the turbulence intensity in the vortex finder is significantly reduced, the tangential velocity of the external vortex is decreased, and the pressure gradient is reduced. The purpose of this paper is to provide new ideas for the optimal design of the internal components of the cyclone separator.

Effect of Inserting Baffles on the Solid Particle Segregation Behavior in Fluidized Bed Reactor: A Computational Study

In multi-solid, particle-size fluidized bed reactor systems, segregation is commonly observed. When segregation occurred, small solid particles were entrained to the top of the bed and escaped from the reactor. During the combustion process, the small solid particles that escaped from the boiler were burned and subjected to damage around the cyclone separator. This study then employed a computational fluid dynamics approach to investigate solid particle behavior in the reactor using three different sizes of solid particles. The effects of baffle insertion, baffle angle, stage number, and its arrangement were examined. The percentage of segregation was calculated to compare behavior among different reactor systems. The insertion of 45-degree baffles resulted in reduced segregation behavior compared to cases without baffles and with 90-degree baffles, attributed to solid hindering and collision phenomena. Additionally, a double-stage baffle with any arrangement could reduce segregation behavior. The best arrangement was “above-arrangement” due to particles hindering, swirling, and accumulating between the baffle stages. Therefore, to diminish segregation behavior and enhance combustion chemical reactions, the insertion of baffles in the reactor zone is recommended.

A simple air-liquid interface exposure system for exposing cultured human 3D epidermis and cornea to PM2.5 collected through cyclonic separation.

Particulate matter (PM) is among the major air pollutants suspended in the atmosphere. PM2.5 has a particle size of 2.5 µm; it is known to cause inflammation, especially in the respiratory tract and skin. Since the skin acts a primary barrier against harmful environmental substances that may enter the body, it is highly exposed to PM2.5 present in the environment. However, the adverse health effects of PM2.5 exposure on human skin have not been accurately examined due to the lack of a system that exposes human epidermal tissue to the actual environmental concentration of PM2.5. In this study, we developed an air-liquid interface exposure system for exposing cultured human 3D epidermis and cornea to PM2.5 collected through cyclonic separation. PM2.5 suspension was nebulized in an acrylic chamber, and the resulting mist was pumped through a diffusion dryer into a glass exposure chamber. A particle counter was connected to the exposure chamber to continuously measure the spatial mass concentration of PM. Human 3D epidermis was cultured in the exposure chamber. Exposure of the human 3D epidermis to PM aerosol increased interleukin-8 release into the media around 50 µg/m3. Mass concentrations above 100 µg/m3 caused cell death. Furthermore, a human corneal model showed similar responses against PM2.5 exposure as 3D epidermis. The air-liquid interface exposure system developed in this study is considered useful for evaluating the health effects induced by environmental PM2.5 and can be used as an alternative to experiments involving actual human or animals.

Effects of different oil return pipe locations on the vortex characteristics of a cylindrical cyclone separator

The optimization of internal components in the oil-gas separator is crucial for enhancing the performance of the compressor system. In this reported study, the effects of three different oil return pipe locations on the vortex characteristics of a cylindrical cyclone separator are investigated by CFD simulation based on the omega method, and the relationship with the separation performance is analyzed. The vortex deformation and breakup near the oil return pipe are evident, with the degree following the order of C > B > A, which is conducive to reducing pressure loss. Cyclone C, with the inclined return pipe, exhibits the lowest pressure drop. The overall separation efficiency follows the sequence of A > B > C. For oil droplets of 5 ?m and larger, the separation efficiency is essentially the same, exceeding 97.5%. Cyclone A exhibits the best separation effect for oil droplets smaller than 5?m. This study provides some references for optimizing the internals of oil separators.

Study on the design of the cyclone separator

Study on the design of the cyclone separator

Parameter matching and experiment of the combined cyclone separation and cylinder sieve cleaning system for rapeseed combine harvester

Parameter matching and experiment of the combined cyclone separation and cylinder sieve cleaning system for rapeseed combine harvester

Innovative technologies combating with dust emission releasing into the atmosphere

An examination of various approaches, methods, and technologies recommended as optimal for safeguarding atmospheric air against dust pollution has led to the identification of the distinct advantages associated with vortex inertial dust collectors utilizing swirling currents. These collectors, referred to as Cyclone Separation Fans (CSF), have been determined to serve as primary and auxiliary equipment in dust removal systems within the production of building materials and other industries. Traditionally employed circuit designs for dust collection systems were also subject to analysis, revealing two prevalent types: open and partially closed air circulation systems. In the latter, a portion of the cleaned airflow is reintroduced into the system, representing a key feature of the design. This assessment underscores the significance of vortex inertial dust collectors, specifically CSFs, as instrumental components in dust removal systems across various industrial sectors. Their effectiveness in mitigating dust pollution, coupled with their versatility as both primary and supplementary equipment, positions them as recommended technologies for atmospheric air protection in the production of building materials and other related industries. The recognition of open and partially closed air circulation systems in traditional dust collection circuit designs further contributes to refining and optimizing dust removal processes for enhanced environmental protection.

Design and Simulation of a High-Efficiency Cyclone Separator for Bioaerosol Collection

Design and Simulation of a High-Efficiency Cyclone Separator for Bioaerosol Collection