Smart Systems are composed of interconnected nodes (devices, services, components, etc.) that can be intelligent, mobile, embedded, cloud-based, or/and adaptive. These nodes interact together through new communication protocols. Architectures of such system needs to adapt its behavior and deals with change in the environment. An adaptive and reconfigurable architecture can repair itself if any execution problems occur, in order to successfully complete its own execution. In the design of an adaptive and reconfigurable software system, several aspects have to be considered. Also other emerging areas such as Big data can also be used to solve traditional problems of Smart Systems, like scalability and performance. This special issue addresses these issues and is composed of seven papers. The paper of1 entitled “Efficient monitoring for intrusion detection in wireless sensor networks” addresses the design of a reliable and energy-efficient monitoring system that resists internal security attacks based on a distributed smart monitoring protocol. The paper of2 entitled “Cloud SLA negotiation and re-negotiation: An ontology-based context-aware approach” defines a context-aware system that automates the negotiation of dynamically generated and adapted SLAs using reasoning techniques and semantic mapping between client requests and provider offers. The paper of3 entitled “Cloud service composition using minimal unsatisfiability and genetic algorithm” targets the run-time phase of adaptive systems. It addresses the dynamic properties of service-oriented adaptive systems by provide a hybrid approach for automatic WS composition based on formal methods and genetic algorithms. The paper of4 entitled “A knowledge-based approach to manage configurable business processes” targets both run-time and design-time as well as structural and behavioral properties of enterprise systems modelled and enacted as Business Processes (BP). It proposes a knowledge-based approach for capturing the different versions of a BP into a single configurable BP and splitting this process into fragments as an alternative of handling multiple BP versions. The paper of5 entitled “Avoiding resource misallocations in business processes” presents an approach for avoiding resource misallocations, considered as an improper combination of resources, in Business Processes (BPs). The paper of6 entitled “Simulating systems of systems using situation/reaction paradigm” targets the designs-time phase of adaptive systems. It considers the paradigm of Systems of Systems that can be applied to different smart and adaptive systems. The paper sees these systems from the mission point of view to characterise their evolving rules with formal modelling and simulation. The paper of7 entitled “A comprehensive survey on modeling of cyber-physical systems” provides a survey of existing approaches to modeling CPS. It aims to study and to classify the CPS properties and to discuss their importance in different application domains. We would like to thank CCPE Editor-in-Chief Dr. Geoffrey C. Fox for his strong support. A special thank goes to all authors for their valuable contributions to this special issue. Special thanks go to all the guest eidtorial board members for their comments that helped in enhancing the quality of the papers.