Novel methods are discussed for the state control of atoms coupled to multi-mode reservoirs with non-Markovian spectra: 1) Excitation decay control : we point out that the quantum Zeno effect, i.e., inhibition of spontaneous decay by frequent measurements, is observable in open cavities and waveguides using a sequence of evolution- interrupting pulses or randomly-modulated CW fields. 2) Location-dependent interference of decay channels - nonadiabatic (resonant) control : We show that the control of populations and coherences of two metastable states is feasible via resonant single-photon absorption to an intermediate state, by controlled spontaneous emission in a cavity. 3) Decoherence control by conditionally interfering parallel evolutions: We demonstrate that an arbitrary internal atomic state can be completely protected from decoherence by interference of its interactions with the reservoir over many different time interals in parallel . Such interference is conditional upon the detection of appropriate atomic-momentum observables. Realization in cavities is suggested. The rich arsenal of control methods described above can improve the performance of single-atom devices. It can also advance the state-of-the-art of quantum information encoding and processing.