This contribution presents the INFN Pisa group research and development efforts aimed at defining and implementing a novel Real-time Control System (RCS) for next-generation interferometers, focusing on the initial phase of the Einstein Telescope (ET) gravitational wave detector. The RCS handles complex closed-loop systems, managing data collection from sensing elements, processing and actuator control within well defined time constraints. It integrates multiple spatially distributed control units, facilitating communications among them, with external systems as well as with users. Two distinct hardware approaches are explored: “Katane” and “Zancle”. These systems primarily differ in their core processing elements. The “Katane” system is built on powerful DSP processor boards, based on the Super-Attenuator control system, developed at INFN Pisa for Advanced Virgo detector. It uses the MicroTCA.4 architecture standard, ensuring flexibility, easy maintenance, and fast data exchange among the various custom modules, including several types of Front-End data converter boards, FPGA-based pre-processing boards, DSPs and standard processors. On the other hand, ”Zancle” explores GPU-based processing, aiming to use cost-effective consumer market systems and to leverage substantial computational power of these devices, also incorporating machine learning algorithms.