BackgroundMulticenter studies conducted in developed countries demonstrated that custom-made devices are safe, effective, and durable for treating complex abdominal aneurysms. However, the situation in developing countries, such as Brazil, is different. Funding and time to have the endoprosthesis delivered are the major concerns. In order to overcome these conditions, high-volume Brazilian university hospitals started gaining experience with a custom-made device produced in the country. ObjectiveThe present study aimed to describe the practice of two tertiary centers and report the early results of fenestrated and branched endovascular repair of complex aortic aneurysms with a custom-made national device available in the Brazilian public health system. MethodsRetrospective analysis of all consecutive patients that underwent F/BEVAR of complex aortic aneurysms using custom-made manufactured endoprosthesis in two tertiary centers from January 2020 to July 2022. ResultsThirteen cases were included (10 male, mean age 69 ± 9 years). 70 % were complex abdominal aneurysms, and 30% were type II, III and IV thoracoabdominal aneurysms (mean aneurysm diameter 69.2 ± 8.12 mm). F/BEVAR included 33 visceral arteries. The Apolo® device was used in all cases. Technical success was achieved in 12 out of 13 patients (92.3%). Thirty-day major adverse events included one death (7.7%), five acute renal failure (38.4%), two spinal cord ischemia (15.4%). The one-year survival rate was 92.3%. ConclusionFenestrated and branched endovascular repair of complex aortic aneurysms with the custom-made Apolo® device has proven safe and effective in high-volume tertiary centers in the Brazilian public health system. Considering the complexity of the cases, the early patency of vessels and low initial mortality support this device continuation and expansion to treat complex aortic aneurysms in a developing country.