Traditionally, two competing claims have arisen that attempt to explain the role of political sophistication in media effectiveness. I reassess the positive versus negative impacts of political sophistication on media priming effects by considering a curvilinear approach. I combine public opinion data (National Election Studies) on candidate selection criteria in 1992 and 2000 presidential elections with content analyses of campaign news coverage to see which segment of voters at different sophistication levels is most susceptible to media agendas. Quadratic regression analyses reveal that an inverted U-shaped relationship exists between voters' susceptibility to campaign news and their level of political sophistication. Such a curvilinear relationship means that the moderately sophisticated are more likely to accept news agendas than the least or most sophisticated. The findings illuminate the long-standing debate about the inconsistent linear relationships between the two variables, providing a more cogent explanation underlying media priming effects.