Vocabulary memorizing is the foundation of English learning, and improving students’ vocabulary memorizing efficiency occupies an essential place in English learning. However, the current vocabulary teaching activities are stereotyped in design and superficial in practice and fail to achieve the teaching goal of improving students’ vocabulary learning ability. With the development of AI, its function for learning is obvious. Therefore, based on AIGC, this study designs an experiment with 60 students from two parallel classes in grade one of a high school in Pingjiang County as the research object. The author adopts the literature method, investigation method, and experimental method. After referring to lots of related literature at home and abroad and conducting the investigation and analysis of the current situation of English vocabulary learning, the design principles and strategies for this experiment are put forward. At the end of the practice, the English vocabulary test and questionnaire survey were used as research tools to collect experimental data, and the SPSS27.0 software was used for statistics and analysis. The results show that AIGC can stimulate students’ interest in vocabulary memorizing, promote memorizing efficiency, and enhance the ability to use the vocabulary.